# |
Marker Acc |
Omim Id |
Gene Id |
Gene Symbol |
Gene Name |
Phenotype Name |
1 |
MGI:1345167 |
611754 |
23923  |
Aadat | aminoadipate aminotransferase |
early eyelid opening |
2 |
MGI:109424 |
601691 |
11304  |
Abca4 | ATP-binding cassette, sub-family A (ABC1), member 4 |
abnormal retinal rod cell morphologyabnormal eye physiology |
3 |
MGI:2386607 |
|
217265  |
Abca5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
exophthalmos |
4 |
MGI:1351634 |
603234 |
27421  |
Abcc6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
abnormal Bruch membrane morphologyretinal calcification |
5 |
MGI:106913 |
606442 |
329165  |
Abi2 | abl-interactor 2 |
microphthalmiaabnormal lens morphologydisorganized secondary lens fibersabnormal lens capsule morphologyabnormal lens development |
6 |
MGI:87872 |
|
104371  |
Acc | anterior capsular cataract |
cataractsabnormal pupil morphology |
7 |
MGI:1100867 |
601784 |
11418  |
Accn1 | amiloride-sensitive cation channel 1, neuronal (degenerin) |
retinal degenerationabnormal eye electrophysiology |
8 |
MGI:87876 |
100740 |
11423  |
Ache | acetylcholinesterase |
eyelids fail to open |
9 |
MGI:87909 |
102620 |
11475  |
Acta2 | actin, alpha 2, smooth muscle, aorta |
abnormal rod electrophysiologyabnormal cone electrophysiology |
10 |
MGI:102806 |
102581 |
11480  |
Acvr2a | activin receptor IIA |
abnormal eyelid morphologycyclopia |
11 |
MGI:1333882 |
605548 |
11490  |
Adam15 | a disintegrin and metallopeptidase domain 15 (metargidin) |
abnormal retinal vasculatureresistance to induced choroidal neovascularization |
12 |
MGI:1096335 |
603639 |
11491  |
Adam17 | a disintegrin and metallopeptidase domain 17 |
eyelids open at birthabnormal conjunctiva morphologyabnormal cornea morphologyeye inflammationabnormal eye morphology |
13 |
MGI:105376 |
602713 |
11502  |
Adam9 | a disintegrin and metallopeptidase domain 9 (meltrin gamma) |
eyelids open at birth |
14 |
MGI:1100819 |
159557 |
17355  |
Aff1 | AF4/FMR2 family, member 1 |
cataracts |
15 |
MGI:2159437 |
606830 |
67269  |
Agtpbp1 | ATP/GTP binding protein 1 |
retinal degenerationabnormal retinal layer morphologyretinal photoreceptor degeneration |
16 |
MGI:1349419 |
300169 |
26926  |
Aifm1 | apoptosis-inducing factor, mitochondrion-associated 1 |
retinal degenerationabnormal eye electrophysiologyretinal ganglion cell degenerationamacrine cell degenerationthin retinal inner plexiform layerthin retinal outer plexiform layer |
17 |
MGI:2148800 |
604392 |
114230  |
Aipl1 | aryl hydrocarbon receptor-interacting protein-like 1 |
abnormal retinal photoreceptor morphologyabnormal retinal cone cell morphologyretinal degenerationdecreased retinal photoreceptor cell numberabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal outer plexiform layer morphologyabnormal rod electrophysiologyabnormal Muller cell morphologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyabnormal retinal bipolar cell morphologydecreased retinal cone cell numberretinal photoreceptor degenerationretinal rod cell degenerationthin retinal outer nuclear layer |
18 |
MGI:1338803 |
607358 |
11634  |
Aire | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) |
increased incidence of corneal inflammationretinal degenerationabnormal lacrimal gland morphologyabnormal lacrimal gland physiologyeye inflammationuveitislacrimal gland inflammation |
19 |
MGI:1313266 |
601662 |
11658  |
Alcam | activated leukocyte cell adhesion molecule |
abnormal retina morphologyabnormal photoreceptor outer segment morphologyabnormal retinal ganglion layer morphology |
20 |
MGI:1353450 |
100640 |
11668  |
Aldh1a1 | aldehyde dehydrogenase family 1, subfamily A1 |
abnormal eye developmentabnormal lens morphologyabnormal retina morphologyabnormal eyelid morphologyabnormal vitreous bodyabnormal corneal stroma developmentabnormal periocular mesenchyme morphologyabnormal posterior eye segment morphologyabnormal corneal stroma morphologyabsent Harderian gland |
21 |
MGI:107928 |
603687 |
19378  |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 |
abnormal optic cup morphology |
22 |
MGI:1861722 |
600463 |
56847  |
Aldh1a3 | aldehyde dehydrogenase family 1, subfamily A3 |
abnormal lens morphologyabnormal retina morphologyabnormal vitreous bodyabnormal periocular mesenchyme morphologyabsent Harderian gland |
23 |
MGI:87996 |
|
107785  |
Alm | anterior lenticonus with microphthalmia |
microphthalmiaabnormal lens morphologycataractsfused cornea and lenscorneal opacityabnormal iris morphologylenticonus |
24 |
MGI:1934606 |
606844 |
236266  |
Alms1 | Alstrom syndrome 1 homolog (human) |
abnormal retinal outer nuclear layer morphologyabnormal eye physiologyabnormal eye electrophysiology |
25 |
MGI:104621 |
601527 |
216285  |
Alx1 | ALX homeobox 1 |
eyelids open at birth |
26 |
MGI:108359 |
605420 |
11695  |
Alx4 | aristaless-like homeobox 4 |
abnormal eye morphology |
27 |
MGI:88025 |
106410 |
109676  |
Ank2 | ankyrin 2, brain |
optic nerve atrophydisorganized secondary lens fibers |
28 |
MGI:1333879 |
603401 |
11774  |
Ap3b1 | adaptor-related protein complex 3, beta 1 subunit |
anophthalmiacataractsabnormal eye pigmentationabnormal eye movementsabnormal visionabnormal eye morphologyreduced eye pigmentation |
29 |
MGI:107734 |
607246 |
11776  |
Ap3d1 | adaptor-related protein complex 3, delta 1 subunit |
reduced eye pigmentationabnormal retinal pigment epithelium morphology |
30 |
MGI:1306796 |
602233 |
11783  |
Apaf1 | apoptotic peptidase activating factor 1 |
persistence of hyaloid capillary systemsmall lensabnormal lens polarityretina hyperplasiaabnormal retinal neuronal layer morphology |
31 |
MGI:1353624 |
300297 |
30878  |
Apln | apelin |
anophthalmia |
32 |
MGI:88048 |
|
104237  |
Apo | anterior polar opacity |
cataractscorneal opacitypupil opacity |
33 |
MGI:2152879 |
|
117587  |
Apoca | anterior polar cataract |
cataracts |
34 |
MGI:88057 |
107741 |
11816  |
Apoe | apolipoprotein E |
abnormal retinal inner nuclear layer morphologyabnormal eye electrophysiologythin retinal inner nuclear layerthin retinal outer nuclear layer |
35 |
MGI:107387 |
600308 |
11829  |
Aqp4 | aquaporin 4 |
abnormal eye electrophysiologyretinal ischemia |
36 |
MGI:88068 |
104640 |
11839  |
Areg | amphiregulin |
microphthalmiaeyelids open at birthcorneal opacity |
37 |
MGI:1929699 |
604695 |
56350  |
Arl3 | ADP-ribosylation factor-like 3 |
retinal outer nuclear layer degenerationabsent photoreceptor outer segment |
38 |
MGI:1096381 |
602550 |
11865  |
Arntl | aryl hydrocarbon receptor nuclear translocator-like |
abnormal eye electrophysiology |
39 |
MGI:2159617 |
301770 |
170735  |
Arr3 | arrestin 3, retinal |
abnormal cone electrophysiology |
40 |
MGI:99473 |
107940 |
109689  |
Arrb1 | arrestin, beta 1 |
abnormal rod electrophysiologyabnormal retinal rod cell outer segment morphology |
41 |
MGI:88075 |
611542 |
11881  |
Arsb | arylsulfatase B |
abnormal cornea morphologyabnormal corneal epithelium morphology |
42 |
MGI:1333791 |
603886 |
11876  |
Artn | artemin |
blepharoptosis |
43 |
MGI:88079 |
|
104385  |
Asc1 | anterior suture cataract 1 |
abnormal lens morphologycataractsabnormal pupil morphology |
44 |
MGI:88080 |
|
104386  |
Asc2 | anterior suture cataract 2 |
abnormal lens morphologycataractsabnormal pupil morphology |
45 |
MGI:87914 |
608034 |
11484  |
Aspa | aspartoacylase |
abnormal retinal ganglion layer morphologyabnormal retinal nerve fiber layer morphology |
46 |
MGI:109349 |
123811 |
11909  |
Atf2 | activating transcription factor 2 |
eye inflammation |
47 |
MGI:88096 |
604064 |
11911  |
Atf4 | activating transcription factor 4 |
microphthalmiaabnormal lens morphologyabnormal iris morphologyabnormal lens fiber morphologyaphakiaabnormal ciliary body morphologyeyelids fail to openabnormal lens developmentincreased lens epithelium apopotosis |
48 |
MGI:1355553 |
609875 |
53404  |
Atoh7 | atonal homolog 7 (Drosophila) |
abnormal retinal cone cell morphologyabnormal eye developmentabnormal retina morphologyabsent optic nerveabnormal retinal vasculatureabnormal optic vesicle formationabnormal amacrine cell morphologyabnormal retinal ganglion layer morphologyabnormal eye electrophysiologyabnormal retinal bipolar cell morphologyabnormal retinal rod bipolar cell morphologyabnormal retinal cone bipolar cell morphologyabnormal retinal nerve fiber layer morphologydecreased retinal ganglion cell numberabnormal retinal ganglion cell morphologyabsent retinal ganglion cellincreased amacrine cell numberincreased retinal cone cell numberdecreased retinal rod cell numberabsent retinal ganglion layerthin retinal inner nuclear layerthin retinal inner plexiform layerthin retinal outer nuclear layerthin retinal outer plexiform layer |
49 |
MGI:88109 |
182331 |
11932  |
Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
abnormal retinal photoreceptor morphologyretinal degenerationeyelids fail to openretinal photoreceptor degenerationthin retinal outer nuclear layerretinal outer nuclear layer degenerationshort photoreceptor inner segmentshort photoreceptor outer segment |
50 |
MGI:2179277 |
607640 |
246103  |
Atxn7 | ataxin 7 |
abnormal retinal rod cell morphologydecreased retinal photoreceptor cell numberblepharoptosisthin retinal inner plexiform layershort photoreceptor outer segment |
51 |
MGI:1270862 |
604025 |
12006  |
Axin2 | axin2 |
abnormal eye morphology |
52 |
MGI:109617 |
604823 |
12023  |
Barx2 | BarH-like homeobox 2 |
eyelids open at birth |
53 |
MGI:1277215 |
209901 |
52028  |
Bbs1 | Bardet-Biedl syndrome 1 (human) |
abnormal retinal photoreceptor morphologyretinal degenerationabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiologyretinal outer nuclear layer degenerationphotoreceptor inner segment degenerationdisorganized photoreceptor inner segment |
54 |
MGI:2135267 |
606151 |
67378  |
Bbs2 | Bardet-Biedl syndrome 2 (human) |
retinal degenerationabnormal eye electrophysiologydisorganized photoreceptor outer segment |
55 |
MGI:2143311 |
600374 |
102774  |
Bbs4 | Bardet-Biedl syndrome 4 (human) |
optic nerve atrophyabnormal retina morphologyretinal degenerationabnormal retinal vasculatureabnormal ocular fundus morphologyabnormal retinal photoreceptor layerabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal cone electrophysiologyabnormal posterior eye segment morphologyabnormal retinal pigment epithelium morphologyabnormal eye electrophysiology |
56 |
MGI:1929913 |
606558 |
58208  |
Bcl11b | B-cell leukemia/lymphoma 11B |
eyelids open at birth |
57 |
MGI:88138 |
151430 |
12043  |
Bcl2 | B-cell leukemia/lymphoma 2 |
abnormal optic nerve morphologyabnormal retinal vasculatureretinal ganglion cell degeneration |
58 |
MGI:88145 |
113505 |
12064  |
Bdnf | brain derived neurotrophic factor |
delayed eyelid opening |
59 |
MGI:1346332 |
607854 |
24115  |
Best1 | bestrophin 1 |
abnormal eye physiologyabnormal eye electrophysiology |
60 |
MGI:2387588 |
607335 |
212989  |
Best2 | bestrophin 2 |
abnormal intraocular pressureocular hypotension |
61 |
MGI:2656732 |
|
  |
Bfc | batface |
ocular hypertelorism |
62 |
MGI:101770 |
603307 |
12075  |
Bfsp1 | beaded filament structural protein 1, in lens-CP94 |
cataractsabnormal lens fiber morphology |
63 |
MGI:1333828 |
603212 |
107993  |
Bfsp2 | beaded filament structural protein 2, phakinin |
cataractsabnormal eye morphologyabnormal cornea/lens morphologyabnormal lens fiber morphology |
64 |
MGI:2153710 |
609331 |
140489  |
Bhlhb4 | basic helix-loop-helix domain containing, class B4 |
abnormal eye electrophysiologyabnormal retinal apoptosisabnormal retinal rod bipolar cell morphology |
65 |
MGI:1930001 |
|
59058  |
Bhlhb5 | basic helix-loop-helix domain containing, class B5 |
abnormal retinal cone bipolar cell morphologydecreased amacrine cell numberthin retinal inner nuclear layer |
66 |
MGI:108093 |
601997 |
12122  |
Bid | BH3 interacting domain death agonist |
abnormal cornea morphologycorneal scarring |
67 |
MGI:1929883 |
606396 |
57784  |
Bin3 | bridging integrator 3 |
cataractsabnormal lens fiber morphology |
68 |
MGI:88168 |
|
109548  |
Bld | blind |
eyelids open at birthabnormal cornea morphology |
69 |
MGI:2678952 |
609762 |
232946  |
Bloc1s3 | biogenesis of lysosome-related organelles complex-1, subunit 3 |
abnormal eye pigmentation |
70 |
MGI:88180 |
112262 |
12159  |
Bmp4 | bone morphogenetic protein 4 |
abnormal eye developmentabnormal lens inductionpersistence of hyaloid capillary systemanophthalmiamicrophthalmiacataractsabnormal cornea morphologycorneal opacityirregularly shaped pupillarge pupilsabnormal iris morphologyabnormal retina morphologyabnormal optic nerve morphologyabsent optic nerveabnormal eye morphologyabnormal eye sizeabnormal vitreous bodyopacity of vitreous bodyabnormal retinal vasculatureretinal detachmentabnormal retinal photoreceptor layerabnormal iridocorneal anglehypoplastic trabecular meshworkabsent trabecular meshworkabsent Schlemm's canaleyelids fail to openabnormal anterior eye segment morphologyabnormal posterior eye segment morphologyabnormal canal of Schlemm morphologyocular hypertensioncorneal thinningabnormal eye electrophysiologyiris hypoplasiacorneal adhesion to irisabnormal placement of pupilsabnormal line of Schwalbethin retinal ganglion layerthin retinal inner nuclear layer |
71 |
MGI:103302 |
112267 |
12162  |
Bmp7 | bone morphogenetic protein 7 |
abnormal lens vesicle developmentanophthalmiamicrophthalmiaaphakiaabnormal retinal pigmentationeyelids fail to openabnormal retinal pigment epithelium morphology |
72 |
MGI:1920480 |
608699 |
73230  |
Bmper | BMP-binding endothelial regulator |
microphthalmia |
73 |
MGI:1338938 |
601299 |
12166  |
Bmpr1a | bone morphogenetic protein receptor, type 1A |
eyelids open at birth |
74 |
MGI:107191 |
603248 |
12167  |
Bmpr1b | bone morphogenetic protein receptor, type 1B |
abnormal eye developmentanophthalmiaabnormal retina morphologyabnormal retinal pigment epithelium morphologyabnormal retinal apoptosisabnormal retinal ganglion cell morphology |
75 |
MGI:1097164 |
601930 |
12173  |
Bnc1 | basonuclin 1 |
abnormal corneal epithelium morphology |
76 |
MGI:1888520 |
608749 |
57261  |
Brd4 | bromodomain containing 4 |
microphthalmiacataracts |
77 |
MGI:1333889 |
602860 |
12236  |
Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) |
cataracts |
78 |
MGI:1343463 |
603719 |
12237  |
Bub3 | budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) |
cataracts |
79 |
MGI:88227 |
120700 |
12266  |
C3 | complement component 3 |
abnormal eye electrophysiology |
80 |
MGI:1920910 |
608965 |
73660  |
Cabp4 | calcium binding protein 4 |
abnormal retinal rod cell morphologyabnormal retinal cone cell morphologyabnormal retina morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye physiologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyabnormal retinal rod bipolar cell morphologyabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layerthin retinal outer plexiform layer |
81 |
MGI:1859639 |
300110 |
54652  |
Cacna1f | calcium channel, voltage-dependent, alpha 1F subunit |
abnormal retinal outer nuclear layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiologyabnormal horizontal cell morphologyabnormal retinal neuronal layer morphologyabnormal retinal rod bipolar cell morphologyabnormal retinal ganglion cell morphologythin retinal outer plexiform layerdisorganized retinal outer plexiform layer |
82 |
MGI:2442632 |
608171 |
319734  |
Cacna2d4 | calcium channel, voltage-dependent, alpha 2/delta subunit 4 |
abnormal retinal layer morphologyabnormal retinal outer nuclear layer morphologyabnormal retinal outer plexiform layer morphologyabnormal retinal inner plexiform layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiologythin retinal outer plexiform layer |
83 |
MGI:894644 |
600003 |
12296  |
Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit |
decreased retinal photoreceptor cell numberabnormal retinal neuronal layer morphology |
84 |
MGI:103301 |
601949 |
12298  |
Cacnb4 | calcium channel, voltage-dependent, beta 4 subunit |
abnormal eye electrophysiology |
85 |
MGI:3521994 |
|
  |
Cal7 | caracul-like 7 |
abnormal eye pigmentation |
86 |
MGI:107739 |
600636 |
12367  |
Casp3 | caspase 3 |
abnormal eye developmentanophthalmiamicrophthalmiacataractsabnormal eye morphologyabnormal lens epithelium morphologyabnormal retinal inner nuclear layer morphologyabnormal pigment epithelium of the eyeabnormal lens developmentdecreased retinal rod cell numberthick retinal outer nuclear layer |
87 |
MGI:1312921 |
601532 |
12368  |
Casp6 | caspase 6 |
abnormal lens development |
88 |
MGI:1351351 |
601199 |
12374  |
Casr | calcium-sensing receptor |
cataracts |
89 |
MGI:88273 |
|
109752  |
Cat3 | dominant cataract 3 |
microphthalmiaabnormal lens morphologysmall pupilsabnormal iris morphology |
90 |
MGI:88040 |
|
109738  |
Cat4 | dominant cataract 4 |
abnormal eye developmentabnormal lens vesicle developmentmicrophthalmiaabnormal lens morphologycataractsfused cornea and lensabnormal cornea morphologycorneal opacityirregularly shaped pupilabnormal iris morphologyabnormal pupillary reflexabnormal corneal stroma morphologyabnormal corneal endothelium morphology |
91 |
MGI:98786 |
|
109748  |
Cat5 | dominant cataract 5 |
cataracts |
92 |
MGI:1928990 |
|
  |
Cat6 | dominant cataract 6 |
cataracts |
93 |
MGI:88285 |
236200 |
12411  |
Cbs | cystathionine beta-synthase |
abnormal eye developmentdelayed eyelid openingmicrophthalmia |
94 |
MGI:88313 |
168461 |
12443  |
Ccnd1 | cyclin D1 |
abnormal retina morphologydisorganized retinal layersretina hypoplasiaabnormal eye electrophysiologythin retinal ganglion layerdisorganized retinal ganglion layer |
95 |
MGI:107542 |
|
110045  |
Ccw | cataract and curly whiskers |
abnormal lens morphologycataractsabnormal lens fiber morphology |
96 |
MGI:107899 |
173510 |
12491  |
Cd36 | CD36 antigen |
ocular pterygiumendophthalmitis |
97 |
MGI:106211 |
116952 |
12540  |
Cdc42 | cell division cycle 42 homolog (S. cerevisiae) |
abnormal eye development |
98 |
MGI:1890219 |
605516 |
22295  |
Cdh23 | cadherin 23 (otocadherin) |
abnormal eye electrophysiology |
99 |
MGI:104772 |
116953 |
12566  |
Cdk2 | cyclin-dependent kinase 2 |
abnormal eye morphology |
100 |
MGI:104556 |
116899 |
12575  |
Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) |
abnormal lens epithelium morphologyabnormal Harderian gland morphologyabnormal lens development |
101 |
MGI:104565 |
600778 |
12576  |
Cdkn1b | cyclin-dependent kinase inhibitor 1B |
abnormal retinal photoreceptor morphologydisorganized retinal layersabnormal retinal pigment epithelium morphologyabnormal Muller cell morphologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyincreased amacrine cell number |
102 |
MGI:104564 |
600856 |
12577  |
Cdkn1c | cyclin-dependent kinase inhibitor 1C (P57) |
abnormal retina morphologyabnormal lens epithelium morphologyabnormal lens developmentincreased lens epithelium apopotosis |
103 |
MGI:104738 |
600160 |
12578  |
Cdkn2a | cyclin-dependent kinase inhibitor 2A |
abnormal retinal photoreceptor morphologypersistence of hyaloid capillary systemmicrophthalmiaabnormal lens morphologycataractsabnormal retina morphologyabnormal eye morphologyabnormal vitreous bodyretinal detachmentabnormal lens capsule morphologyabnormal retinal inner nuclear layer morphologyabnormal posterior eye segment morphologyabnormal retinal ganglion layer morphologyabnormal lens developmentabnormal retinal neuronal layer morphology |
104 |
MGI:103572 |
600749 |
110794  |
Cebpe | CCAAT/enhancer binding protein (C/EBP), epsilon |
conjunctivitis |
105 |
MGI:1923799 |
607576 |
330409  |
Cecr2 | cat eye syndrome chromosome region, candidate 2 homolog (human) |
absent eyelids |
106 |
MGI:1100883 |
604523 |
12614  |
Celsr1 | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) |
absent eyelids |
107 |
MGI:2384917 |
610142 |
216274  |
Cep290 | centrosomal protein 290 |
abnormal retina morphologyretinal degenerationabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal pigment epithelium of the eyethin retinal outer nuclear layerphotoreceptor outer segment degeneration |
108 |
MGI:101757 |
601442 |
12631  |
Cfl1 | cofilin 1, non-muscle |
abnormal eye development |
109 |
MGI:88388 |
602421 |
12638  |
Cftr | cystic fibrosis transmembrane conductance regulator homolog |
abnormal lacrimal gland morphology |
110 |
MGI:88242 |
|
104146  |
Cgct | congenital cataract |
cataracts |
111 |
MGI:2444748 |
|
320790  |
Chd7 | chromodomain helicase DNA binding protein 7 |
dry eyesabnormal optic eminence morphology |
112 |
MGI:892979 |
300390 |
12662  |
Chm | choroidermia |
abnormal retina morphologydecreased retinal photoreceptor cell numberabnormal photoreceptor outer segment morphologyabnormal rod electrophysiologyabnormal retinal pigmentationabnormal retinal pigment epithelium morphologyretinal photoreceptor degenerationthin retinal outer nuclear layershort photoreceptor outer segment |
113 |
MGI:88397 |
118493 |
243764  |
Chrm2 | cholinergic receptor, muscarinic 2, cardiac |
mydriasis |
114 |
MGI:88398 |
118494 |
12671  |
Chrm3 | cholinergic receptor, muscarinic 3, cardiac |
mydriasis |
115 |
MGI:87887 |
118503 |
110834  |
Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 |
microphthalmiamydriasisabnormal eyelid apertureeyelids fail to openimpaired pupilary reflex |
116 |
MGI:87891 |
118507 |
11444  |
Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) |
mydriasisabnormal eyelid apertureeyelids fail to openimpaired pupilary reflex |
117 |
MGI:1931825 |
604817 |
56773  |
Chst5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
abnormal cornea morphologydecreased corneal stroma thicknessabnormal corneal stroma morphologycorneal thinning |
118 |
MGI:99484 |
600664 |
12675  |
Chuk | conserved helix-loop-helix ubiquitous kinase |
eyelids open at birthabnormal conjunctiva morphologyabnormal eyelid morphologyabnormal anterior eye segment morphologyabnormal corneal stroma morphologyabnormal corneal epithelium morphology |
119 |
MGI:1306784 |
602937 |
17684  |
Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
abnormal iris morphologycoloboma |
120 |
MGI:105061 |
600570 |
12724  |
Clcn2 | chloride channel 2 |
retinal degenerationabnormal photoreceptor outer segment morphologyabnormal retinal outer nuclear layer morphologyabnormal eye physiologydisorganized photoreceptor inner segmentdisorganized photoreceptor outer segment |
121 |
MGI:103555 |
600580 |
12725  |
Clcn3 | chloride channel 3 |
retinal degenerationdecreased retinal photoreceptor cell numberblindnessabnormal eye morphologyabnormal eye physiologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyphotoreceptor inner segment degenerationphotoreceptor outer segment degenerationdisorganized photoreceptor outer segment |
122 |
MGI:1347048 |
602727 |
26373  |
Clcn7 | chloride channel 7 |
optic nerve atrophyretinal degeneration |
123 |
MGI:88419 |
|
107485  |
Cle | closed eyes and microphthalmia |
abnormal eye developmentmicrophthalmiaabnormal eye morphology |
124 |
MGI:107537 |
607042 |
12752  |
Cln3 | ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) |
abnormal retina morphologyretinal degenerationdecreased retinal photoreceptor cell numberabnormal retinal inner nuclear layer morphologyabnormal retinal ganglion layer morphologyabnormal retinal neuronal layer morphologyabnormal retinal ganglion cell morphology |
125 |
MGI:2442253 |
608102 |
211286  |
Cln5 | ceroid-lipofuscinosis, neuronal 5 |
abnormal vision |
126 |
MGI:2159324 |
606725 |
76524  |
Cln6 | ceroid-lipofuscinosis, neuronal 6 |
retinal degeneration |
127 |
MGI:1349447 |
607837 |
26889  |
Cln8 | ceroid-lipofuscinosis, neuronal 8 |
retinal degenerationblindnessabnormal retinal photoreceptor layerabnormal retinal pigment epithelium morphologyabnormal retinal rod cell inner segment morphologyabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layershort photoreceptor inner segmentshort photoreceptor outer segment |
128 |
MGI:88431 |
116955 |
12785  |
Cnbp | cellular nucleic acid binding protein |
anophthalmia |
129 |
MGI:1341818 |
600053 |
12790  |
Cnga3 | cyclic nucleotide gated channel alpha 3 |
abnormal retinal rod cell morphologydecreased retinal photoreceptor cell numbermiotic pupilsabnormal pupillary reflexabnormal eye physiologyabnormal eye electrophysiologyabnormal horizontal cell morphologyabnormal retinal neuronal layer morphologyabnormal retinal rod bipolar cell morphologyabnormal retinal cone cell outer segment morphologyretinal photoreceptor degeneration |
130 |
MGI:2664102 |
600724 |
333329  |
Cngb1 | cyclic nucleotide gated channel beta 1 |
decreased retinal photoreceptor cell numberabnormal rod electrophysiologyabnormal horizontal cell morphologyabnormal retinal rod bipolar cell morphologyretinal photoreceptor degenerationabnormal retinal rod cell outer segment morphology |
131 |
MGI:1929230 |
605695 |
117197  |
Cno | cappuccino |
abnormal eye pigmentationabnormal choroid pigmentationabnormal retinal pigmentation |
132 |
MGI:88442 |
|
109792  |
Coc | coralliform cataract |
cataracts |
133 |
MGI:88451 |
120328 |
12822  |
Col18a1 | collagen, type XVIII, alpha 1 |
persistence of hyaloid capillary systemabnormal retina morphologyabnormal eye morphologyabnormal lens development |
134 |
MGI:88467 |
120150 |
12842  |
Col1a1 | collagen, type I, alpha 1 |
ocular hypertension |
135 |
MGI:88452 |
120140 |
12824  |
Col2a1 | collagen, type II, alpha 1 |
disorganized retinal layers |
136 |
MGI:88454 |
120130 |
12826  |
Col4a1 | collagen, type IV, alpha 1 |
cataractsabnormal cornea morphologycorneal opacityirregularly shaped pupilabnormal retina morphologyabnormal eye morphologyabnormal eye size |
137 |
MGI:104688 |
120070 |
12828  |
Col4a3 | collagen, type IV, alpha 3 |
abnormal lens morphology |
138 |
MGI:88458 |
120190 |
12832  |
Col5a2 | collagen, type V, alpha 2 |
abnormal cornea morphology |
139 |
MGI:88463 |
120251 |
12837  |
Col8a1 | collagen, type VIII, alpha 1 |
abnormal cornea morphologydecreased corneal stroma thicknessabnormal Descemet membraneabnormal anterior eye segment morphologyabnormal eye anterior chamberabnormal corneal endothelium morphologycorneal thinning |
140 |
MGI:88464 |
120252 |
329941  |
Col8a2 | collagen, type VIII, alpha 2 |
abnormal Descemet membrane |
141 |
MGI:2136343 |
604210 |
170788  |
Crb1 | crumbs homolog 1 (Drosophila) |
abnormal retinal photoreceptor morphologyabnormal retina morphologyretinal degenerationdecreased retinal photoreceptor cell numberphotosensitivityabnormal ocular fundus morphologyabnormal retinal photoreceptor layerabnormal photoreceptor inner segment morphologyabnormal retinal outer nuclear layer morphologyabnormal retinal inner nuclear layer morphologyabnormal Muller cell morphologythin retinal outer nuclear layershort photoreceptor inner segmentphotoreceptor outer segment degenerationshort photoreceptor outer segment |
142 |
MGI:1354756 |
606189 |
50766  |
Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) |
small lensabnormal optic cup morphologyabnormal posterior eye segment morphology |
143 |
MGI:104686 |
602007 |
12929  |
Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
ocular hypertelorism |
144 |
MGI:3529431 |
|
230872  |
Crocc | ciliary rootlet coiled-coil, rootletin |
retinal photoreceptor degeneration |
145 |
MGI:2662567 |
|
  |
Crsl | carousel |
dry eyes |
146 |
MGI:1194883 |
602225 |
12951  |
Crx | cone-rod homeobox containing gene |
abnormal retinal photoreceptor morphologyabnormal retina morphologyabnormal retinal photoreceptor layerabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal outer plexiform layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiologyabnormal horizontal cell morphologyabnormal retinal bipolar cell morphologyabnormal retinal rod bipolar cell morphologyabnormal retinal cone bipolar cell morphologythin retinal outer nuclear layerabsent photoreceptor outer segment |
147 |
MGI:1270841 |
601933 |
12952  |
Cry1 | cryptochrome 1 (photolyase-like) |
abnormal retina morphologyretinal degenerationabnormal retinal outer nuclear layer morphologyimpaired pupilary reflexdecreased retinal cone cell numberabsent retinal rod cellsabsent photoreceptor outer segment |
148 |
MGI:1270859 |
603732 |
12953  |
Cry2 | cryptochrome 2 (photolyase-like) |
impaired pupilary reflex |
149 |
MGI:88515 |
123580 |
12954  |
Cryaa | crystallin, alpha A |
microphthalmiaabnormal lens morphologycataractssmall lensabnormal lens fiber morphologyincreased lens epithelium apopotosisincreased lens fiber apoptosis |
150 |
MGI:88516 |
123590 |
12955  |
Cryab | crystallin, alpha B |
abnormal lens morphology |
151 |
MGI:88518 |
123610 |
12957  |
Cryba1 | crystallin, beta A1 |
microphthalmiacataracts |
152 |
MGI:88519 |
123620 |
12961  |
Crybb2 | crystallin, beta B2 |
abnormal lens morphologycataractssmall lensabnormal lens fiber morphology |
153 |
MGI:88521 |
123660 |
12964  |
Cryga | crystallin, gamma A |
microphthalmiaabnormal lens morphologycataractsabnormal lens fiber morphologyruptured lens capsule |
154 |
MGI:88522 |
123670 |
12965  |
Crygb | crystallin, gamma B |
abnormal lens morphologycataractsabnormal lens fiber morphology |
155 |
MGI:88523 |
123680 |
12966  |
Crygc | crystallin, gamma C |
microphthalmiaabnormal lens morphologycataractsabnormal lens fiber morphology |
156 |
MGI:88524 |
123690 |
12967  |
Crygd | crystallin, gamma D |
abnormal lens morphologycataractssmall lensabnormal lens fiber morphologyocular rupture |
157 |
MGI:88525 |
|
12968  |
Cryge | crystallin, gamma E |
microphthalmiaabnormal lens morphologycataractssmall lenssmall pupilsabnormal iris morphologyabnormal lens fiber morphologyabnormal lens development |
158 |
MGI:88526 |
|
12969  |
Crygf | crystallin, gamma F |
cataracts |
159 |
MGI:1298216 |
123730 |
12970  |
Crygs | crystallin, gamma S |
abnormal lens morphologycataractsdisorganized secondary lens fibersabnormal lens fiber morphology |
160 |
MGI:88537 |
124095 |
12988  |
Csk | c-src tyrosine kinase |
abnormal lens induction |
161 |
MGI:88543 |
115440 |
12995  |
Csnk2a1 | casein kinase 2, alpha 1 polypeptide |
abnormal eye developmentabnormal optic vesicle formationabnormal optic stalk morphology |
162 |
MGI:109514 |
601145 |
13014  |
Cstb | cystatin B |
abnormal cornea morphologyincreased incidence of corneal inflammationcorneal opacitycorneal scarringabnormal eye physiologyuveitis |
163 |
MGI:88276 |
116806 |
12387  |
Ctnnb1 | catenin (cadherin associated protein), beta 1 |
dry eyesabnormal eyelid morphologyconjunctivitisblindnessabnormal eye morphologyearly eyelid openingabnormal Harderian gland morphologynarrow eye openingabnormal corneal stroma morphologyabnormal corneal epithelium morphologykeratoconjunctivitisabsent meibomian glands |
164 |
MGI:1915756 |
607758 |
67087  |
Ctnnbip1 | catenin beta interacting protein 1 |
anophthalmia |
165 |
MGI:105100 |
601045 |
12388  |
Ctnnd1 | catenin (cadherin associated protein), delta 1 |
abnormal lacrimal gland morphology |
166 |
MGI:1932872 |
606272 |
83429  |
Ctns | cystinosis, nephropathic |
abnormal retinal pigmentationcorneal depositsabnormal eye electrophysiology |
167 |
MGI:88562 |
116840 |
13033  |
Ctsd | cathepsin D |
abnormal retina morphologyblindnessretinal photoreceptor degeneration |
168 |
MGI:88564 |
116880 |
13039  |
Ctsl | cathepsin L |
corneal opacity |
169 |
MGI:88590 |
601771 |
13078  |
Cyp1b1 | cytochrome P450, family 1, subfamily b, polypeptide 1 |
abnormal iridocorneal anglesynechiahypoplastic trabecular meshworkabsent Schlemm's canalabnormal trabecular meshwork morphologyabnormal canal of Schlemm morphology |
170 |
MGI:2176159 |
605207 |
232174  |
Cyp26b1 | cytochrome P450, family 26, subfamily b, polypeptide 1 |
eyelids open at birth |
171 |
MGI:106091 |
118455 |
13122  |
Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 |
delayed eyelid openingabnormal vision |
172 |
MGI:1929651 |
|
56790  |
D3Ertd300e | DNA segment, Chr 3, ERATO Doi 300, expressed |
abnormal retinal pigment epithelium morphology |
173 |
MGI:108554 |
603448 |
13131  |
Dab1 | disabled homolog 1 (Drosophila) |
abnormal retinal inner nuclear layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal retinal rod bipolar cell morphology |
174 |
MGI:94864 |
609312 |
13166  |
Dbh | dopamine beta hydroxylase |
blepharoptosis |
175 |
MGI:94869 |
120470 |
13176  |
Dcc | deleted in colorectal carcinoma |
abnormal optic nerve morphologyabnormal optic nerve innervationabnormal retinal pigmentation |
176 |
MGI:1202384 |
600045 |
13194  |
Ddb1 | damage specific DNA binding protein 1 |
abnormal lens morphologycataractsabnormal lens epithelium morphologyincreased lens epithelium apopotosis |
177 |
MGI:1921997 |
607729 |
74747  |
Ddit4 | DNA-damage-inducible transcript 4 |
abnormal retinal vasculatureabnormal retinal apoptosis |
178 |
MGI:1345277 |
191311 |
18214  |
Ddr2 | discoidin domain receptor family, member 2 |
exophthalmos |
179 |
MGI:2138334 |
601826 |
227333  |
Dgkd | diacylglycerol kinase, delta |
eyelids open at birth |
180 |
MGI:1934609 |
|
245905  |
Dilp3 | dilated pupils 3 |
abnormal eye morphologymydriasis |
181 |
MGI:1934610 |
|
245906  |
Dilp4 | dilated pupils 4 |
abnormal eye morphologymydriasis |
182 |
MGI:1916147 |
607502 |
68897  |
Disp1 | dispatched homolog 1 (Drosophila) |
cyclopia |
183 |
MGI:1329040 |
605189 |
13380  |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) |
abnormal eye developmentanophthalmiaabnormal optic vesicle formation |
184 |
MGI:1890663 |
605415 |
56811  |
Dkk2 | dickkopf homolog 2 (Xenopus laevis) |
abnormal cornea morphologycorneal opacityabnormal corneal epithelium morphology |
185 |
MGI:107231 |
601014 |
13383  |
Dlg1 | discs, large homolog 1 (Drosophila) |
abnormal lens epithelium morphology |
186 |
MGI:94900 |
176290 |
13386  |
Dlk1 | delta-like 1 homolog (Drosophila) |
narrow eye opening |
187 |
MGI:101926 |
600028 |
13395  |
Dlx5 | distal-less homeobox 5 |
abnormal eye developmentmicrophthalmia |
188 |
MGI:101927 |
600030 |
13396  |
Dlx6 | distal-less homeobox 6 |
abnormal eye developmentmicrophthalmia |
189 |
MGI:94909 |
300377 |
13405  |
Dmd | dystrophin, muscular dystrophy |
abnormal Muller cell morphologyabnormal eye electrophysiologyretinal ischemia |
190 |
MGI:892995 |
611203 |
13002  |
Dnajc5 | DnaJ (Hsp40) homolog, subfamily C, member 5 |
blindnessabnormal visionabnormal retinal outer plexiform layer morphologyabnormal eye electrophysiologyretinal photoreceptor degenerationthin retinal outer nuclear layer |
191 |
MGI:1913283 |
608057 |
56629  |
Dnase2b | deoxyribonuclease II beta |
cataractsabnormal vision |
192 |
MGI:1261819 |
602900 |
13436  |
Dnmt3b | DNA methyltransferase 3B |
ocular hypertelorism |
193 |
MGI:2652871 |
|
68813  |
Dock5 | dedicator of cytokinesis 5 |
cataracts |
194 |
MGI:2151233 |
603527 |
116905  |
Dph1 | DPH1 homolog (S. cerevisiae) |
abnormal eye pigmentationabnormal eye morphology |
195 |
MGI:1928392 |
125597 |
56429  |
Dpt | dermatopontin |
decreased corneal stroma thicknessabnormal posterior stroma morphologyabnormal corneal stroma morphologycorneal thinning |
196 |
MGI:109173 |
125643 |
13505  |
Dsc1 | desmocollin 1 |
microphthalmiaeyelids open at birthcorneal opacity |
197 |
MGI:1196281 |
602523 |
13508  |
Dscam | Down syndrome cell adhesion molecule |
abnormal retinal inner plexiform layer morphologyabnormal amacrine cell morphologydisorganized retinal ganglion layer |
198 |
MGI:99499 |
169615 |
13512  |
Dsg3 | desmoglein 3 |
conjunctivitis |
199 |
MGI:104627 |
113810 |
13518  |
Dst | dystonin |
abnormal eye distance/ positionenophthalmos |
200 |
MGI:1929270 |
609114 |
56431  |
Dstn | destrin |
cataractsabnormal cornea/lens morphologycorneal vascularizationabnormal corneal epithelium morphology |
201 |
MGI:2137586 |
607145 |
94245  |
Dtnbp1 | dystrobrevin binding protein 1 |
abnormal eye pigmentationabnormal choroid morphologyabnormal choroid pigmentationabnormal retinal pigment epithelium morphology |
202 |
MGI:101941 |
189971 |
13555  |
E2f1 | E2F transcription factor 1 |
abnormal eye developmentabnormal retina morphologyabnormal retinal inner plexiform layer morphologyabnormal cone electrophysiologyabnormal amacrine cell morphologyabnormal retinal progenitor morphologyabnormal retinal bipolar cell morphologydecreased retinal ganglion cell numberthin retinal outer nuclear layer |
203 |
MGI:3032536 |
|
  |
Eccp | eccentric pupil |
abnormal lens morphologycorneal opacityirregularly shaped pupilretinal degenerationabnormal pupillary reflex |
204 |
MGI:1101357 |
600423 |
230857  |
Ece1 | endothelin converting enzyme 1 |
abnormal choroid pigmentation |
205 |
MGI:1195272 |
300451 |
13607  |
Eda | ectodysplasin-A |
abnormal cornea morphologyincreased incidence of corneal inflammationcorneal opacityabnormal eyelid morphologyeye inflammationconjunctivitisblindnessabnormal eye morphologyblepharitisnarrow eye openingcorneal vascularizationabnormal corneal epithelium morphologyabsent meibomian glands |
206 |
MGI:1343498 |
604095 |
13608  |
Edar | ectodysplasin-A receptor |
cataractsabsent meibomian glands |
207 |
MGI:1931001 |
606603 |
171211  |
Edaradd | EDAR (ectodysplasin-A receptor)-associated death domain |
abnormal cornea morphologycorneal opacityabnormal eyelid morphologynarrow eye openingabsent meibomian glands |
208 |
MGI:102720 |
131244 |
13618  |
Ednrb | endothelin receptor type B |
abnormal eye pigmentationabnormal choroid pigmentation |
209 |
MGI:1339998 |
601548 |
216616  |
Efemp1 | epidermal growth factor-containing fibulin-like extracellular matrix protein 1 |
abnormal eye morphologyretinal detachmentabnormal retinal pigment epithelium morphologyabnormal Bruch membrane morphologyretinal pigment epithelium atrophyabnormal choriocapillaris morphology |
210 |
MGI:2449923 |
608582 |
353156  |
Egfl7 | EGF-like domain 7 |
abnormal retinal vasculature |
211 |
MGI:2146149 |
|
268780  |
Egflam | EGF-like, fibronectin type III and laminin G domains |
abnormal retinal rod cell morphologyabnormal retinal cone cell morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye physiology |
212 |
MGI:95294 |
131550 |
13649  |
Egfr | epidermal growth factor receptor |
microphthalmiaeyelids open at birthabnormal lens morphologyfused cornea and lensabnormal cornea morphologycorneal opacitycorneal scarringabnormal retina morphologyabsent eyelidsabnormal eye morphologyabnormal lens fiber morphologyabnormal ciliary body morphologyabnormal eye anterior chambercorneal thinningcorneal adhesion to iris |
213 |
MGI:1932288 |
606426 |
112407  |
Egln3 | EGL nine homolog 3 (C. elegans) |
abnormal pupil morphology |
214 |
MGI:95296 |
129010 |
13654  |
Egr2 | early growth response 2 |
delayed eyelid opening |
215 |
MGI:1306780 |
602419 |
13655  |
Egr3 | early growth response 3 |
blepharoptosis |
216 |
MGI:1933331 |
605512 |
83603  |
Elovl4 | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 |
abnormal retina morphologyabnormal visionabnormal eye morphologyabnormal retinal photoreceptor layerabnormal photoreceptor outer segment morphologyabnormal retinal outer plexiform layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal retinal pigment epithelium morphologyabnormal eye electrophysiologyretinal cone cell degenerationretinal photoreceptor degenerationretinal rod cell degenerationabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layer |
217 |
MGI:95319 |
|
104017  |
Em | Emory cataract |
cataracts |
218 |
MGI:95388 |
600035 |
13797  |
Emx2 | empty spiracles homolog 2 (Drosophila) |
abnormal lens morphologyretina hyperplasia |
219 |
MGI:95391 |
|
104374  |
Enc | embryonic nucleus cataract |
cataracts |
220 |
MGI:1201683 |
604615 |
13813  |
Eomes | eomesodermin homolog (Xenopus laevis) |
abnormal optic nerve morphologyabnormal retinal apoptosisdecreased retinal ganglion cell numberabnormal retinal ganglion cell morphologythin retinal ganglion layer |
221 |
MGI:1276116 |
602700 |
328572  |
Ep300 | E1A binding protein p300 |
microphthalmia |
222 |
MGI:1096337 |
600600 |
270190  |
Ephb1 | Eph receptor B1 |
abnormal optic nerve innervationabnormal eye morphology |
223 |
MGI:99611 |
600997 |
13844  |
Ephb2 | Eph receptor B2 |
abnormal eye morphology |
224 |
MGI:104770 |
601839 |
13845  |
Ephb3 | Eph receptor B3 |
abnormal eye morphology |
225 |
MGI:95413 |
126340 |
13871  |
Ercc2 | excision repair cross-complementing rodent repair deficiency, complementation group 2 |
corneal opacity |
226 |
MGI:1100494 |
609413 |
319955  |
Ercc6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 |
abnormal retina morphologyretinal degenerationphotosensitivityabnormal retinal outer nuclear layer morphologyabnormal retinal inner nuclear layer morphology |
227 |
MGI:1919241 |
609412 |
71991  |
Ercc8 | excision repaiross-complementing rodent repair deficiency, complementation group 8 |
retinal photoreceptor degeneration |
228 |
MGI:107508 |
602061 |
13874  |
Ereg | epiregulin |
eyelids open at birth |
229 |
MGI:1921405 |
608069 |
74155  |
Errfi1 | ERBB receptor feedback inhibitor 1 |
delayed eyelid opening |
230 |
MGI:109344 |
601653 |
14048  |
Eya1 | eyes absent 1 homolog (Drosophila) |
eyelids open at birth |
231 |
MGI:1341823 |
607139 |
14087  |
Fanca | Fanconi anemia, complementation group A |
microphthalmia |
232 |
MGI:2448480 |
227646 |
211651  |
Fancd2 | Fanconi anemia, complementation group D2 |
microphthalmia |
233 |
MGI:95484 |
134637 |
14102  |
Fas | Fas (TNF receptor superfamily member 6) |
abnormal conjunctiva morphologyabnormal lacrimal gland morphologyconjunctivitisabnormal conjunctival epitheliumlacrimal gland inflammation |
234 |
MGI:99255 |
134638 |
14103  |
Fasl | Fas ligand (TNF superfamily, member 6) |
eye inflammationabnormal eye electrophysiology |
235 |
MGI:109168 |
600976 |
14107  |
Fat1 | FAT tumor suppressor homolog 1 (Drosophila) |
anophthalmiamicrophthalmiaaphakiacyclopiaretinal pigment epithelium atrophyabnormal retinal neuronal layer morphology |
236 |
MGI:2147134 |
607871 |
225055  |
Fbxo11 | F-box protein 11 |
eyelids open at birth |
237 |
MGI:1099809 |
602115 |
14165  |
Fgf10 | fibroblast growth factor 10 |
eyelids open at birth |
238 |
MGI:95523 |
176943 |
14183  |
Fgfr2 | fibroblast growth factor receptor 2 |
ocular hypertelorismeyelids open at birthabsent eyelidsabsent lacrimal glandsexophthalmos |
239 |
MGI:1890647 |
605295 |
60344  |
Fign | fidgetin |
abnormal eye developmentmicrophthalmiasmall lensabnormal cornea morphologycorneal opacityabnormal retina morphologyabsent lacrimal glandseye inflammationconjunctivitisabnormal Harderian gland morphologyabnormal meibomian gland morphologycorneal vascularization |
240 |
MGI:1341070 |
604840 |
14232  |
Fkbp8 | FK506 binding protein 8 |
anophthalmiamicrophthalmia |
241 |
MGI:95556 |
300017 |
192176  |
Flna | filamin, alpha |
irregularly shaped pupilabnormal eye morphologymydriasis |
242 |
MGI:95558 |
165070 |
14254  |
Flt1 | FMS-like tyrosine kinase 1 |
corneal vascularization |
243 |
MGI:1328364 |
600245 |
14264  |
Fmod | fibromodulin |
corneal opacityabnormal eye sizeabnormal sclera morphologysclera thinning |
244 |
MGI:95568 |
136430 |
14275  |
Folr1 | folate receptor 1 (adult) |
absent optic vesicle |
245 |
MGI:95574 |
164810 |
14281  |
Fos | FBJ osteosarcoma oncogene |
abnormal eye electrophysiologydecreased retinal rod cell numberthin retinal outer nuclear layer |
246 |
MGI:1347476 |
600288 |
15376  |
Foxa2 | forkhead box A2 |
abnormal optic vesicle formationabsent optic vesicle |
247 |
MGI:1347466 |
601090 |
17300  |
Foxc1 | forkhead box C1 |
abnormal eye developmentmicrophthalmiaeyelids open at birthabnormal lens morphologycataractssmall lensabnormal cornea morphologyirregularly shaped pupillarge pupilsabnormal iris morphologyabnormal lacrimal gland morphologyabnormal lacrimal gland physiologyabnormal eye morphologyabnormal iridocorneal anglesynechiahypoplastic trabecular meshworkabsent Schlemm's canalabnormal ciliary body morphologyabnormal anterior eye segment morphologyabnormal aqueous drainage system morphologyabnormal iris pigment epitheliumabnormal trabecular meshwork morphologyabnormal canal of Schlemm morphologyabnormal eye anterior chamberabnormal corneal endothelium morphologycorneal vascularizationabnormal corneal epithelium morphologyiris hypoplasiairis stroma hypoplasiacorneal adhesion to irisabnormal placement of pupilsabnormal line of Schwalbe |
248 |
MGI:1347481 |
602402 |
14234  |
Foxc2 | forkhead box C2 |
cataractsabnormal iris morphologyblepharoptosisperiorbital edemaabnormal eye morphologyocular distichiasiscorneal abrasionabnormal iridocorneal angleabnormal iris pigment epitheliumabnormal trabecular meshwork morphologyabnormal canal of Schlemm morphologyabnormal orbit morphologyiris stroma hypoplasia |
249 |
MGI:1347463 |
601091 |
15229  |
Foxd1 | forkhead box D1 |
abnormal retina morphology |
250 |
MGI:1347473 |
611539 |
15221  |
Foxd3 | forkhead box D3 |
eyelids open at birth |
251 |
MGI:1353569 |
601094 |
30923  |
Foxe3 | forkhead box E3 |
abnormal lens inductionabnormal lens vesicle developmentmicrophthalmiaabnormal lens morphologycataractssmall lensfused cornea and lensabnormal cornea morphologycorneal opacitysmall pupilsabnormal iris morphologyabnormal retina morphologyabnormal pupillary reflexabnormal lens fiber morphologyabnormal lens epithelium morphologyabnormal iridocorneal angleabsent trabecular meshworkabsent corneal endotheliumabnormal ciliary body morphologyeyelids fail to openabnormal anterior eye segment morphologyabnormal canal of Schlemm morphologyabnormal eye anterior chamberabnormal corneal stroma morphologyabnormal corneal endothelium morphologycorneal vascularizationabnormal lens developmentabnormal corneal epithelium morphologyiris hypoplasiacorneal adhesion to iris |
252 |
MGI:1347464 |
164874 |
15228  |
Foxg1 | forkhead box G1 |
abnormal eye developmentabnormal retina morphologyabnormal eye morphologyabnormal retinal neuronal layer morphology |
253 |
MGI:1349428 |
605597 |
26927  |
Foxl2 | forkhead box L2 |
eyelids open at birthabnormal eyelid morphology |
254 |
MGI:2151057 |
609429 |
116810  |
Foxn4 | forkhead box N4 |
retina hypoplasiaabnormal retinal neuronal layer morphologyincreased retinal photoreceptor cell numberabnormal retinal apoptosisabnormal retinal ganglion cell morphologydecreased amacrine cell numberabsent horizontal cells |
255 |
MGI:2148705 |
605317 |
114142  |
Foxp2 | forkhead box P2 |
delayed eyelid opening |
256 |
MGI:1891436 |
300292 |
20371  |
Foxp3 | forkhead box P3 |
delayed eyelid openingconjunctivitisblepharitisnarrow eye opening |
257 |
MGI:2385368 |
607830 |
231470  |
Fras1 | Fraser syndrome 1 homolog (human) |
microphthalmiaabsent eyelidscryptophthalmos |
258 |
MGI:2670972 |
608944 |
329872  |
Frem1 | Fras1 related extracellular matrix protein 1 |
abnormal eye developmentanophthalmiaeyelids open at birthabnormal retina morphologyabsent eyelidsabnormal eye morphologyearly eyelid openingcryptophthalmos |
259 |
MGI:2444465 |
608945 |
242022  |
Frem2 | Fras1 related extracellular matrix protein 2 |
anophthalmiamicrophthalmiacryptophthalmos |
260 |
MGI:1100860 |
607743 |
327826  |
Frs2 | fibroblast growth factor receptor substrate 2 |
anophthalmiamicrophthalmia |
261 |
MGI:2443337 |
607643 |
238021  |
Fscn2 | fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) |
abnormal retina morphologyretinal degenerationabnormal photoreceptor outer segment morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiologythin retinal inner nuclear layerthin retinal outer nuclear layershort photoreceptor outer segment |
262 |
MGI:95586 |
136470 |
14313  |
Fst | follistatin |
thin retinal ganglion layer |
263 |
MGI:95602 |
137025 |
14360  |
Fyn | Fyn proto-oncogene |
abnormal optic nerve morphology |
264 |
MGI:108520 |
604579 |
14366  |
Fzd4 | frizzled homolog 4 (Drosophila) |
abnormal vitreous bodyabnormal retinal vasculatureretinal hemorrhage |
265 |
MGI:108571 |
601723 |
14367  |
Fzd5 | frizzled homolog 5 (Drosophila) |
retinal degeneration |
266 |
MGI:108474 |
603409 |
14368  |
Fzd6 | frizzled homolog 6 (Drosophila) |
eyelids open at birth |
267 |
MGI:108088 |
604439 |
14388  |
Gab1 | growth factor receptor bound protein 2-associated protein 1 |
eyelids open at birthabsent eyelidsearly eyelid opening |
268 |
MGI:95625 |
137161 |
14408  |
Gabrr1 | gamma-aminobutyric acid (GABA-C) receptor, subunit rho 1 |
abnormal eye morphology |
269 |
MGI:1355303 |
253000 |
50917  |
Galns | galactosamine (N-acetyl)-6-sulfate sulfatase |
abnormal cornea morphology |
270 |
MGI:95639 |
162060 |
14432  |
Gap43 | growth associated protein 43 |
abnormal optic nerve innervation |
271 |
MGI:95655 |
139185 |
14451  |
Gas1 | growth arrest specific 1 |
abnormal eye developmentmicrophthalmiasmall lensabnormal cornea morphologyabnormal iris morphologyabnormal eye pigmentationabnormal eye morphologyabnormal vitreous bodyabnormal ciliary body morphologyabnormal anterior eye segment morphologyabnormal posterior eye segment morphologyabnormal retinal pigment epithelium morphologyabnormal retinal ganglion layer morphologycolobomanarrow eye openingabnormal retinal neuronal layer morphology |
272 |
MGI:1338027 |
603936 |
14561  |
Gdf11 | growth differentiation factor 11 |
decreased retinal photoreceptor cell numberabnormal optic nerve morphologyincreased retinal ganglion cell numberabnormal choroid morphologyabnormal retinal neuronal layer morphologyabsent amacrine cellsabsent retinal inner plexiform layer |
273 |
MGI:95689 |
601147 |
242316  |
Gdf6 | growth differentiation factor 6 |
abnormal optic disc morphology |
274 |
MGI:1195462 |
601956 |
14586  |
Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 |
dry eyesblepharoptosis |
275 |
MGI:1201403 |
605710 |
14587  |
Gfra3 | glial cell line derived neurotrophic factor family receptor alpha 3 |
blepharoptosis |
276 |
MGI:95706 |
231950 |
14598  |
Ggt1 | gamma-glutamyltransferase 1 |
abnormal lens morphologycataracts |
277 |
MGI:1346063 |
137168 |
23887  |
Ggt5 | gamma-glutamyltransferase 5 |
cataracts |
278 |
MGI:95713 |
121014 |
14609  |
Gja1 | gap junction protein, alpha 1 |
cataractscorneal opacityirregularly shaped pupilabnormal iris morphology |
279 |
MGI:1339969 |
611924 |
14610  |
Gja10 | gap junction protein, alpha 10 |
abnormal eye electrophysiologyabnormal horizontal cell morphology |
280 |
MGI:95714 |
121015 |
14611  |
Gja3 | gap junction protein, alpha 3 |
microphthalmiaabnormal lens morphologycataractsabnormal cornea/lens morphology |
281 |
MGI:99953 |
600897 |
14616  |
Gja8 | gap junction protein, alpha 8 |
abnormal eye developmentmicrophthalmiaabnormal lens morphologycataractssmall lensabnormal eye morphologyabnormal cornea/lens morphologyabnormal lens fiber morphologyabnormal eye physiologyabnormal lens developmentabnormal eye electrophysiologyruptured lens capsule |
282 |
MGI:2153060 |
608803 |
118454  |
Gjc2 | gap junction protein, gamma 2 |
absent optic nerve |
283 |
MGI:1334209 |
607058 |
14617  |
Gjd2 | gap junction protein, delta 2 |
abnormal retinal ganglion layer morphology |
284 |
MGI:1923993 |
|
118446  |
Gje1 | gap junction protein, epsilon 1 |
abnormal lens vesicle developmentmicrophthalmiaabnormal lens morphologycataractssmall lensabnormal cornea morphologycorneal opacityabnormal retina morphologyabnormal lens fiber morphologyabnormal lens development |
285 |
MGI:2136405 |
612134 |
93683  |
Glce | glucuronyl C5-epimerase |
coloboma |
286 |
MGI:95729 |
165240 |
14634  |
Gli3 | GLI-Kruppel family member GLI3 |
abnormal eye developmentanophthalmiaeyelids open at birthabnormal pupil morphologyabnormal retina morphologyabnormal eye sizeabnormal optic vesicle formationabnormal optic stalk morphologyabnormal optic cup morphologyeyelids fail to openabnormal Harderian gland morphology |
287 |
MGI:95747 |
138491 |
14654  |
Glra1 | glycine receptor, alpha 1 subunit |
abnormal cone electrophysiologyabnormal eye electrophysiology |
288 |
MGI:95749 |
600421 |
110304  |
Glra3 | glycine receptor, alpha 3 subunit |
abnormal eye physiology |
289 |
MGI:95775 |
139311 |
14681  |
Gnao1 | guanine nucleotide binding protein, alpha O |
abnormal cone electrophysiologyabnormal eye electrophysiology |
290 |
MGI:95778 |
139330 |
14685  |
Gnat1 | guanine nucleotide binding protein, alpha transducing 1 |
retinal degenerationabnormal rod electrophysiologyabnormal eye physiologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyabnormal retinal rod cell outer segment morphologythin retinal inner nuclear layerthin retinal outer nuclear layer |
291 |
MGI:95779 |
139340 |
14686  |
Gnat2 | guanine nucleotide binding protein, alpha transducing 2 |
abnormal retinal cone cell morphologyabnormal retinal vasculatureabnormal photoreceptor outer segment morphologyabnormal cone electrophysiology |
292 |
MGI:109165 |
189970 |
14699  |
Gngt1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
photosensitivityabnormal rod electrophysiologyabnormal eye electrophysiologyretinal photoreceptor degenerationretinal rod cell degenerationshort photoreceptor outer segment |
293 |
MGI:1343460 |
602744 |
14712  |
Gnpat | glyceronephosphate O-acyltransferase |
persistence of hyaloid capillary systemmicrophthalmiacataractsabnormal optic nerve morphologylenticonusabnormal retinal pigment epithelium morphologyabnormal eye anterior chamber |
294 |
MGI:109602 |
603930 |
268566  |
Gphn | gephyrin |
abnormal retinal inner plexiform layer morphology |
295 |
MGI:1934765 |
604368 |
93695  |
Gpnmb | glycoprotein (transmembrane) nmb |
optic nerve atrophyabnormal iris morphologyabnormal iris pigmentationabnormal iris pigment epitheliumabnormal iris stroma morphologyabnormal intraocular pressureiris atrophyretinal ganglion cell degeneration |
296 |
MGI:107193 |
300500 |
18241  |
Gpr143 | G protein-coupled receptor 143 |
abnormal optic nerve innervationabnormal ocular fundus morphologypresence of melanin granules in retinaabnormal ciliary body pigmentationabnormal iris pigment epitheliumabnormal pigment epithelium of the eyeabnormal retinal pigment epithelium morphology |
297 |
MGI:2685054 |
|
240888  |
Gpr161 | G protein-coupled receptor 161 |
abnormal lens morphologycataracts |
298 |
MGI:1274784 |
602851 |
110789  |
Gpr98 | G protein-coupled receptor 98 |
abnormal visionabnormal cone electrophysiology |
299 |
MGI:2655333 |
608317 |
230824  |
Grhl3 | grainyhead-like 3 (Drosophila) |
eyelids open at birth |
300 |
MGI:1933206 |
606650 |
242443  |
Grin3a | glutamate receptor ionotropic, NMDA3A |
abnormal eye electrophysiology |
301 |
MGI:1921303 |
604597 |
74053  |
Grip1 | glutamate receptor interacting protein 1 |
abnormal eye developmentabnormal lens vesicle developmentanophthalmiamicrophthalmiaeyelids open at birthcataractsabnormal cornea morphologycorneal opacityabnormal iris morphologyabnormal retina morphologyabnormal eyelid morphologyabnormal eye morphologyaphakiacryptophthalmosabnormal corneal stroma morphologyabnormal lens developmentabnormal corneal epithelium morphology |
302 |
MGI:1345146 |
180381 |
24013  |
Grk1 | G protein-coupled receptor kinase 1 |
abnormal retinal rod cell morphologyabnormal retinal rod cell outer segment morphology |
303 |
MGI:1929494 |
605277 |
232906  |
Grlf1 | glucocorticoid receptor DNA binding factor 1 |
microphthalmiaabnormal retina morphologycolobomaretinal pigment epithelium hyperplasia |
304 |
MGI:1351338 |
604473 |
14816  |
Grm1 | glutamate receptor, metabotropic 1 |
narrow eye opening |
305 |
MGI:1351343 |
604096 |
108072  |
Grm6 | glutamate receptor, metabotropic 6 |
abnormal eye electrophysiology |
306 |
MGI:3044668 |
|
450219  |
Gsdma3 | gasdermin A3 |
corneal opacity |
307 |
MGI:3529962 |
|
  |
Gsfaey17 | gsf abnormal eyes 17 |
microphthalmia |
308 |
MGI:95804 |
138300 |
14782  |
Gsr | glutathione reductase |
abnormal retinal vasculature |
309 |
MGI:95842 |
|
14842  |
Gsx1 | GS homeobox 1 |
delayed eyelid opening |
310 |
MGI:104735 |
|
14910  |
Gt(ROSA)26Sor | gene trap ROSA 26, Philippe Soriano |
cataractsretinal degenerationdisorganized retinal layersabnormal optic nerve morphologyabnormal eyelid morphologyabsent eyelidsabnormal vitreous bodyabnormal lens fiber morphologyincreased retinal ganglion cell numberabnormal retinal layer morphologyabnormal eye anterior chambercolobomacorneal vascularizationabnormal retinal neuronal layer morphologyabsent amacrine cellsimpaired pupilary reflexdecreased retinal ganglion cell numberabsent retinal inner plexiform layer |
311 |
MGI:102770 |
600364 |
14913  |
Guca1a | guanylate cyclase activator 1a (retina) |
abnormal eye electrophysiology |
312 |
MGI:1194489 |
602275 |
107477  |
Guca1b | guanylate cyclase activator 1B |
abnormal eye electrophysiology |
313 |
MGI:105123 |
600179 |
14919  |
Gucy2e | guanylate cyclase 2e |
abnormal retinal cone cell morphologyretinal degenerationabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye physiologyabnormal eye electrophysiologyretinal cone cell degenerationdecreased retinal cone cell numberabnormal retinal cone cell inner segment morphologyabnormal retinal cone cell outer segment morphology |
314 |
MGI:105119 |
300041 |
245650  |
Gucy2f | guanylate cyclase 2f |
abnormal retinal rod cell morphologyabnormal rod electrophysiologyretinal cone cell degenerationdecreased retinal cone cell numberabnormal retinal cone cell outer segment morphologyabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layershort photoreceptor outer segment |
315 |
MGI:1353434 |
|
268756  |
Gulo | gulonolactone (L-) oxidase |
cataractsabnormal retina morphology |
316 |
MGI:2384768 |
|
207304  |
Hectd1 | HECT domain containing 1 |
microphthalmiaabnormal eye distance/ positionabnormal eye morphology |
317 |
MGI:1332240 |
300167 |
15203  |
Heph | hephaestin |
abnormal retina morphologyretinal degenerationabnormal retinal vasculatureabnormal choroid morphologyabnormal retinal pigmentationabnormal retinal pigment epithelium morphologyretinal pigment epithelium hyperplasiaretinal photoreceptor degeneration |
318 |
MGI:104853 |
139605 |
15205  |
Hes1 | hairy and enhancer of split 1 (Drosophila) |
disorganized retinal layersabnormal retinal neuronal layer morphologyabsent optic vesicle |
319 |
MGI:104876 |
607348 |
15208  |
Hes5 | hairy and enhancer of split 5 (Drosophila) |
abnormal Muller cell morphology |
320 |
MGI:96071 |
601802 |
15209  |
Hesx1 | homeo box gene expressed in ES cells |
abnormal eye developmentanophthalmiaabnormal eye distance/ positionabnormal eye morphologyabnormal optic cup morphology |
321 |
MGI:96073 |
606869 |
15211  |
Hexa | hexosaminidase A |
corneal opacityabnormal visionabnormal eye morphology |
322 |
MGI:96086 |
604420 |
15242  |
Hhex | hematopoietically expressed homeobox |
anophthalmiaabnormal optic vesicle formationabnormal optic stalk morphology |
323 |
MGI:1099804 |
601767 |
215114  |
Hip1 | huntingtin interacting protein 1 |
microphthalmiacataractssmall lens |
324 |
MGI:1314872 |
606868 |
15258  |
Hipk2 | homeodomain interacting protein kinase 2 |
abnormal lens vesicle development |
325 |
MGI:96113 |
163905 |
15289  |
Hmgb1 | high mobility group box 1 |
eyelids open at birth |
326 |
MGI:96173 |
142959 |
15398  |
Hoxa13 | homeo box A13 |
iris stroma hypoplasia |
327 |
MGI:96177 |
142952 |
15402  |
Hoxa5 | homeo box A5 |
delayed eyelid opening |
328 |
MGI:96183 |
142967 |
103889  |
Hoxb2 | homeo box B2 |
abnormal eye physiology |
329 |
MGI:2177763 |
604982 |
192236  |
Hps1 | Hermansky-Pudlak syndrome 1 homolog (human) |
abnormal eye pigmentationabnormal retina morphologyabnormal choroid pigmentationabnormal ciliary body pigmentation |
330 |
MGI:2153839 |
606118 |
12807  |
Hps3 | Hermansky-Pudlak syndrome 3 homolog (human) |
abnormal eye pigmentation |
331 |
MGI:2177742 |
606682 |
192232  |
Hps4 | Hermansky-Pudlak syndrome 4 homolog (human) |
abnormal eye pigmentationabnormal retinal inner nuclear layer morphologyabnormal choroid pigmentationabnormal retinal pigment epithelium morphology |
332 |
MGI:2180307 |
607521 |
246694  |
Hps5 | Hermansky-Pudlak syndrome 5 homolog (human) |
reduced eye pigmentation |
333 |
MGI:2181763 |
607522 |
20170  |
Hps6 | Hermansky-Pudlak syndrome 6 |
reduced eye pigmentation |
334 |
MGI:1346049 |
604844 |
23908  |
Hs2st1 | heparan sulfate 2-O-sulfotransferase 1 |
abnormal eye developmentcataractsabnormal retinal pigment epithelium morphologycolobomaabnormal retinal ganglion cell morphology |
335 |
MGI:1354958 |
604846 |
50785  |
Hs6st1 | heparan sulfate 6-O-sulfotransferase 1 |
abnormal eye morphologyabnormal retinal ganglion layer morphology |
336 |
MGI:105089 |
601860 |
15488  |
Hsd17b4 | hydroxysteroid (17-beta) dehydrogenase 4 |
cataracts |
337 |
MGI:1347058 |
602438 |
26386  |
Hsf4 | heat shock transcription factor 4 |
microphthalmiaabnormal lens morphologycataractssmall lenshydropic eye lens fibersabnormal lens fiber morphologyabnormal lens capsule morphologyabnormal lens epithelium morphologyectopia lentisruptured lens capsule |
338 |
MGI:1916503 |
602179 |
69253  |
Hspb2 | heat shock protein 2 |
abnormal lens morphology |
339 |
MGI:96257 |
142461 |
15530  |
Hspg2 | perlecan (heparan sulfate proteoglycan 2) |
delayed eyelid openingmicrophthalmia |
340 |
MGI:96305 |
|
104377  |
Iac | iris anomaly with cataract |
microphthalmiacataractsabnormal pupil morphologyabnormal pupillary reflexcolobomaabnormal placement of pupils |
341 |
MGI:96392 |
147840 |
15894  |
Icam1 | intercellular adhesion molecule 1 |
abnormal retina morphologyabnormal retinal vasculatureresistance to induced choroidal neovascularizationabnormal eye physiology |
342 |
MGI:1890528 |
|
207130  |
Icst | iris-corneal strands |
macrophthalmiaabnormal cornea morphologycorneal opacitycorneal scarringirregularly shaped pupilabnormal iris morphologyabnormal eye morphologycorneal adhesion to iris |
343 |
MGI:96399 |
|
107421  |
Idc | iris dysplasia with cataract |
microphthalmiaabnormal lens morphologycataractsfused cornea and lenscorneal opacityabnormal pupil morphologyabnormal iris morphologyeye inflammationabnormal pupillary reflexlenticonus |
344 |
MGI:96418 |
252800 |
15932  |
Idua | iduronidase, alpha-L- |
abnormal orbit morphology |
345 |
MGI:107658 |
107450 |
15975  |
Ifnar1 | interferon (alpha and beta) receptor 1 |
corneal vascularization |
346 |
MGI:107656 |
147570 |
15978  |
Ifng | interferon gamma |
corneal vascularization |
347 |
MGI:1921166 |
606621 |
73916  |
Ift57 | intraflagellar transport 57 homolog (Chlamydomonas) |
ocular hypotelorism |
348 |
MGI:107936 |
600953 |
16173  |
Il18 | interleukin 18 |
abnormal retinal vasculatureretinal hemorrhage |
349 |
MGI:96556 |
147780 |
16189  |
Il4 | interleukin 4 |
lacrimal gland inflammation |
350 |
MGI:105303 |
146928 |
12765  |
Il8rb | interleukin 8 receptor, beta |
corneal vascularization |
351 |
MGI:96570 |
147290 |
16323  |
Inhba | inhibin beta-A |
eyelids open at birthenophthalmos |
352 |
MGI:96571 |
147390 |
16324  |
Inhbb | inhibin beta-B |
delayed eyelid openingeyelids open at birthincreased incidence of corneal inflammationcorneal opacityabnormal eye morphologyabnormal corneal epithelium morphology |
353 |
MGI:96573 |
176730 |
16334  |
Ins2 | insulin II |
abnormal retinal vasculatureabnormal retinal ganglion layer morphologyabnormal retinal neuronal layer morphologyabnormal retinal apoptosis |
354 |
MGI:1859086 |
606195 |
54352  |
Irx5 | Iroquois related homeobox 5 (Drosophila) |
narrow eye openingabnormal retinal cone bipolar cell morphology |
355 |
MGI:101791 |
600366 |
16392  |
Isl1 | ISL1 transcription factor, LIM/homeodomain |
abnormal optic nerve innervationoptic nerve hypoplasiaretinal ganglion cell degeneration |
356 |
MGI:96602 |
605025 |
16400  |
Itga3 | integrin alpha 3 |
abnormal vitreous bodyabnormal lens epithelium morphologyabnormal retinal nerve fiber layer morphologydisorganized retinal ganglion layer |
357 |
MGI:96605 |
147556 |
16403  |
Itga6 | integrin alpha 6 |
abnormal vitreous bodyabnormal retinal nerve fiber layer morphology |
358 |
MGI:96610 |
135630 |
16412  |
Itgb1 | integrin beta 1 (fibronectin receptor beta) |
abnormal eye distance/ position |
359 |
MGI:1306802 |
607153 |
16413  |
Itgb1bp1 | integrin beta 1 binding protein 1 |
exophthalmos |
360 |
MGI:96611 |
600065 |
16414  |
Itgb2 | integrin beta 2 |
abnormal retina morphologyconjunctivitisabnormal retinal vasculatureresistance to induced choroidal neovascularizationabnormal eye physiology |
361 |
MGI:1095416 |
601920 |
16449  |
Jag1 | jagged 1 |
corneal opacityirregularly shaped pupilabnormal eye morphologyabnormal anterior eye segment morphologycolobomaabnormal placement of pupils |
362 |
MGI:1858910 |
604914 |
107817  |
Jmjd6 | jumonji domain containing 6 |
anophthalmia |
363 |
MGI:96646 |
165160 |
16476  |
Jun | Jun oncogene |
eyelids open at birth |
364 |
MGI:1343101 |
602301 |
14534  |
Kat2a | K(lysine) acetyltransferase 2A |
blepharoptosis |
365 |
MGI:96654 |
176260 |
16485  |
Kcna1 | potassium voltage-gated channel, shaker-related subfamily, member 1 |
abnormal lacrimal gland physiologyexcessive tearingeye inflammation |
366 |
MGI:1194504 |
602208 |
16513  |
Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 |
delayed eyelid openingeyelids fail to openabnormal eye physiologyabnormal eye electrophysiology |
367 |
MGI:1202398 |
603288 |
16545  |
Kera | keratocan |
abnormal iridocorneal angleabnormal corneal stroma morphology |
368 |
MGI:96677 |
164920 |
16590  |
Kit | kit oncogene |
abnormal eye pigmentation |
369 |
MGI:96974 |
184745 |
17311  |
Kitl | kit ligand |
abnormal retinal pigmentation |
370 |
MGI:96680 |
190070 |
16653  |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
abnormal eye development |
371 |
MGI:99258 |
|
110026  |
Krd | kidney and retinal defects |
disorganized retinal layersabnormal retinal layer morphologyabnormal eye electrophysiologythin retinal inner nuclear layerthin retinal outer nuclear layer |
372 |
MGI:96687 |
601687 |
268482  |
Krt12 | keratin 12 |
abnormal corneal epithelium morphology |
373 |
MGI:96688 |
148066 |
16664  |
Krt14 | keratin 14 |
abnormal corneal epithelium morphology |
374 |
MGI:96701 |
123940 |
16682  |
Krt4 | keratin 4 |
abnormal corneal epithelium morphology |
375 |
MGI:96721 |
308840 |
16728  |
L1cam | L1 cell adhesion molecule |
excessive tearingdeep-set eyesenophthalmos |
376 |
MGI:99916 |
150325 |
16779  |
Lamb2 | laminin, beta 2 |
abnormal retinal photoreceptor morphologyabnormal retinal rod cell morphologyabnormal retina morphologyabnormal retinal outer plexiform layer morphologyabnormal eye electrophysiologyabnormal retinal apoptosisshort photoreceptor inner segmentshort photoreceptor outer segment |
377 |
MGI:99914 |
150290 |
226519  |
Lamc1 | laminin, gamma 1 |
abnormal retina morphology |
378 |
MGI:1342270 |
603590 |
16795  |
Large | like-glycosyltransferase |
abnormal vitreous bodyabnormal retinal vasculaturevitreal fibroplasiaabnormal retinal layer morphologyabnormal retinal outer plexiform layer morphologyabnormal retinal inner nuclear layer morphologyabnormal retinal ganglion layer morphologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyvitreous body depositiondisorganized retinal ganglion layerthin retinal inner nuclear layerthin retinal outer nuclear layerthin retinal outer plexiform layerdisorganized retinal outer plexiform layer |
379 |
MGI:2138281 |
600024 |
98386  |
Lbr | lamin B receptor |
abnormal eye physiology |
380 |
MGI:2149028 |
|
245904  |
Lcl | lens cloudy |
microphthalmiaabnormal lens morphologycataractsabnormal eye morphology |
381 |
MGI:96765 |
606945 |
16835  |
Ldlr | low density lipoprotein receptor |
retinal detachment |
382 |
MGI:96770 |
153245 |
16842  |
Lef1 | lymphoid enhancer binding factor 1 |
persistence of hyaloid capillary system |
383 |
MGI:104993 |
601007 |
16847  |
Lepr | leptin receptor |
abnormal retina morphologyabnormal retinal vasculatureabnormal intraocular pressureabnormal eye electrophysiology |
384 |
MGI:1891468 |
606666 |
107515  |
Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 |
microphthalmiaeyelids open at birthabnormal lens morphologycataractssmall lensabnormal cornea morphologyincreased incidence of corneal inflammationcorneal opacitylarge pupilsabnormal retina morphologydisorganized secondary lens fibersdecreased corneal stroma thicknessabnormal iridocorneal anglehypoplastic trabecular meshworkabnormal ciliary body morphologyabnormal anterior eye segment morphologyabnormal canal of Schlemm morphologyabnormal corneal stroma morphologycorneal vascularizationcorneal thinningcorneal depositsabnormal corneal epithelium morphologyiris hypoplasiairis stroma hypoplasiacorneal adhesion to irisretinal ganglion cell degenerationthin retinal inner nuclear layerdisorganized retinal inner nuclear layerthin retinal outer nuclear layerdisorganized retinal outer nuclear layer |
385 |
MGI:96785 |
603759 |
16870  |
Lhx2 | LIM homeobox protein 2 |
anophthalmiaabnormal retina morphologyabnormal eye morphologyaphakia |
386 |
MGI:104698 |
154045 |
233187  |
Lim2 | lens intrinsic membrane protein 2 |
microphthalmiaabnormal lens morphologycataractssmall lensdisorganized secondary lens fibersabnormal vitreous bodyabnormal lens fiber morphology |
387 |
MGI:109360 |
603129 |
16911  |
Lmo4 | LIM domain only 4 |
eyelids open at birth |
388 |
MGI:1353586 |
604362 |
380928  |
Lmo7 | LIM domain only 7 |
abnormal retinal photoreceptor layerabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal outer nuclear layer morphologyabnormal retinal pigmentation |
389 |
MGI:1100513 |
602575 |
16917  |
Lmx1b | LIM homeobox transcription factor 1 beta |
microphthalmiairregularly shaped pupilabnormal lens epithelium morphologyabnormal ciliary body morphologyabnormal anterior eye segment morphologyabnormal eye anterior chamberabnormal iris stroma morphologyabnormal corneal stroma morphology |
390 |
MGI:108429 |
602282 |
14745  |
Lpar1 | lysophosphatidic acid receptor 1 |
abnormal eye distance/ positionocular hypertelorism |
391 |
MGI:1891259 |
604863 |
79235  |
Lrat | lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) |
abnormal visionabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiologyabnormal retinal rod cell outer segment morphologyshort photoreceptor outer segment |
392 |
MGI:95794 |
600073 |
14725  |
Lrp2 | low density lipoprotein receptor-related protein 2 |
anophthalmiamicrophthalmia |
393 |
MGI:1278315 |
603506 |
16973  |
Lrp5 | low density lipoprotein receptor-related protein 5 |
abnormal eye developmentpersistence of hyaloid capillary systemabnormal retina morphologyretinal degenerationabnormal retinal vasculatureabnormal retinal layer morphologyabnormal retinal outer nuclear layer morphologyabnormal retinal outer plexiform layer morphologyabnormal retinal pigment epithelium morphologyabnormal retinal nerve fiber layer morphologyretinal ganglion cell degenerationretinal photoreceptor degenerationdisorganized retinal inner nuclear layerthin retinal inner plexiform layerthin retinal outer nuclear layerdisorganized retinal outer nuclear layerthin retinal outer plexiform layerdisorganized retinal outer plexiform layer |
394 |
MGI:1298218 |
603507 |
16974  |
Lrp6 | low density lipoprotein receptor-related protein 6 |
anophthalmiamicrophthalmia |
395 |
MGI:96831 |
|
103996  |
Lse | low set ears |
corneal opacity |
396 |
MGI:1101355 |
602090 |
16998  |
Ltbp3 | latent transforming growth factor beta binding protein 3 |
excessive tearing |
397 |
MGI:109347 |
600616 |
17022  |
Lum | lumican |
abnormal cornea morphologycorneal opacityabnormal eye sizeabnormal sclera morphologydecreased corneal stroma thicknessabnormal posterior stroma morphologyabnormal corneal stroma developmentincreased corneal light-scatteringretinal detachmenthigh myopiasclera thinningabnormal corneal stroma morphology |
398 |
MGI:107448 |
606897 |
17101  |
Lyst | lysosomal trafficking regulator |
abnormal eye pigmentationabnormal retinal layer morphologypresence of melanin granules in retinaabnormal choroid pigmentationabnormal ciliary body pigmentationabnormal iris pigmentationreduced eye pigmentationabnormal iris pigment epitheliumabnormal pigment epithelium of the eyeabnormal retinal pigment epithelium morphology |
399 |
MGI:1333773 |
601280 |
17116  |
Mab21l1 | mab-21-like 1 (C. elegans) |
microphthalmiaabnormal retina morphologyaphakiaaniridia |
400 |
MGI:1346022 |
604357 |
23937  |
Mab21l2 | mab-21-like 2 (C. elegans) |
abnormal retina morphologyaphakiaabnormal retinal pigment epithelium morphologyabnormal lens developmentabnormal retinal progenitor morphology |
401 |
MGI:96909 |
177075 |
17132  |
Maf | avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog |
abnormal lens inductionabnormal lens vesicle developmentmicrophthalmiaabnormal lens morphologycataractssmall lensabnormal cornea morphologysmall pupilsabnormal lens development |
402 |
MGI:892970 |
188860 |
17153  |
Mal | myelin and lymphocyte protein, T-cell differentiation protein |
abnormal optic nerve morphology |
403 |
MGI:107286 |
609458 |
17159  |
Man2b1 | mannosidase 2, alpha B1 |
abnormal retinal photoreceptor morphologyabnormal eye morphologyabnormal eye muscle morphologyabnormal corneal stroma morphologyabnormal corneal endothelium morphology |
404 |
MGI:1346866 |
176872 |
26395  |
Map2k1 | mitogen-activated protein kinase kinase 1 |
eyelids open at birth |
405 |
MGI:1346872 |
600982 |
26401  |
Map3k1 | mitogen-activated protein kinase kinase kinase 1 |
eyelids open at birthabnormal eyelid morphologyabnormal eye morphology |
406 |
MGI:1346861 |
601158 |
26419  |
Mapk8 | mitogen-activated protein kinase 8 |
eyelids open at birthabnormal lens morphologysmall lensabnormal eye morphologycoloboma |
407 |
MGI:97180 |
157140 |
17762  |
Mapt | microtubule-associated protein tau |
cataracts |
408 |
MGI:96907 |
177061 |
17118  |
Marcks | myristoylated alanine rich protein kinase C substrate |
abnormal retina morphology |
409 |
MGI:1928482 |
606516 |
56758  |
Mbnl1 | muscleblind-like 1 (Drosophila) |
cataracts |
410 |
MGI:99420 |
600042 |
17203  |
Mc5r | melanocortin 5 receptor |
abnormal lacrimal gland physiology |
411 |
MGI:1890498 |
605248 |
94178  |
Mcoln1 | mucolipin 1 |
retinal degenerationabnormal optic nerve morphologyabnormal retinal outer nuclear layer morphologythin retinal inner nuclear layerthin retinal inner plexiform layer |
412 |
MGI:1100846 |
604311 |
19014  |
Med1 | mediator complex subunit 1 |
abnormal eye developmentabnormal lens epithelium morphologyabnormal retinal pigmentationabnormal lens development |
413 |
MGI:104717 |
601739 |
17268  |
Meis1 | Meis homeobox 1 |
small lensabnormal retina morphology |
414 |
MGI:2385957 |
606227 |
259172  |
Mfrp | membrane-type frizzled-related protein |
abnormal retina morphologyretinal degenerationretinal photoreceptor degeneration |
415 |
MGI:96990 |
154050 |
17339  |
Mip | major intrinsic protein of eye lens fiber |
microphthalmiaabnormal lens morphologycataractssmall lenshydropic eye lens fibersabnormal lens fiber morphology |
416 |
MGI:104554 |
156845 |
17342  |
Mitf | microphthalmia-associated transcription factor |
abnormal retinal photoreceptor morphologyabnormal eye developmentanophthalmiamicrophthalmiaabnormal lens morphologycataractsabnormal iris morphologyabnormal eye pigmentationabnormal retina morphologyretinal degenerationabsent optic nerveabnormal eyelid morphologyabnormal eye morphologymydriasisabnormal eye sizeabnormal vitreous bodyabnormal ocular fundus morphologyretinal detachmentabnormal photoreceptor inner segment morphologyabnormal rod electrophysiologyabnormal optic stalk morphologyabnormal optic cup morphologyabnormal choroid morphologyabnormal ciliary body morphologyabnormal choroid pigmentationabnormal iris pigmentationabnormal retinal pigmentationreduced eye pigmentationeyelids fail to openabnormal posterior eye segment morphologyabnormal pigment epithelium of the eyeabnormal retinal pigment epithelium morphologyabnormal Harderian gland morphologyabnormal eye physiologycolobomaabnormal iris stromal pigmentationabnormal lens developmentabnormal retinal neuronal layer morphologyocular albinismimpaired pupilary reflexabsent retinal cone cellsretinal photoreceptor degenerationabsent retinal rod cellsabsent photoreceptor outer segment |
417 |
MGI:1891836 |
604896 |
59030  |
Mkks | McKusick-Kaufman syndrome protein |
eyelids open at birthretinal degeneration |
418 |
MGI:2444959 |
606833 |
231051  |
Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 |
delayed eyelid opening |
419 |
MGI:101900 |
600754 |
17387  |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) |
macrophthalmia |
420 |
MGI:2386681 |
606575 |
227157  |
Mpp4 | membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) |
abnormal retinal photoreceptor morphologyabnormal retina morphologyabnormal rod electrophysiology |
421 |
MGI:1306778 |
157129 |
17755  |
Mtap1b | microtubule-associated protein 1B |
delayed eyelid openingabnormal eye morphology |
422 |
MGI:106639 |
607093 |
17769  |
Mthfr | 5,10-methylenetetrahydrofolate reductase |
exophthalmos |
423 |
MGI:2178598 |
607289 |
17828  |
Muted | muted |
abnormal eye pigmentationabnormal retinal pigment epithelium morphology |
424 |
MGI:1930780 |
160776 |
77579  |
Myh10 | myosin, heavy polypeptide 10, non-muscle |
abnormal retina morphologyabnormal retinal bipolar cell morphology |
425 |
MGI:105976 |
160777 |
17918  |
Myo5a | myosin Va |
abnormal eye pigmentation |
426 |
MGI:104785 |
600970 |
17920  |
Myo6 | myosin VI |
abnormal eye electrophysiology |
427 |
MGI:104510 |
276903 |
17921  |
Myo7a | myosin VIIa |
abnormal eye electrophysiology |
428 |
MGI:1202864 |
601652 |
17926  |
Myoc | myocilin |
abnormal intraocular pressure |
429 |
MGI:1858746 |
605880 |
54169  |
Myst4 | MYST histone acetyltransferase monocytic leukemia 4 |
microphthalmiaabnormal lacrimal gland morphology |
430 |
MGI:1351641 |
609701 |
27419  |
Naglu | alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) |
abnormal retina morphologyabnormal sclera morphologyabnormal rod electrophysiologyabnormal retinal pigment epithelium morphologyabnormal eye electrophysiologythin retinal outer nuclear layershort photoreceptor outer segment |
431 |
MGI:109201 |
108345 |
17961  |
Nat2 | N-acetyltransferase 2 (arylamine N-acetyltransferase) |
anophthalmiamicrophthalmiacataractsabnormal eye morphologyaphakia |
432 |
MGI:2183691 |
607026 |
78286  |
Nav2 | neuron navigator 2 |
abnormal optic nerve morphology |
433 |
MGI:97281 |
116930 |
17967  |
Ncam1 | neural cell adhesion molecule 1 |
abnormal retina morphology |
434 |
MGI:1347351 |
608458 |
26562  |
Ncdn | neurochondrin |
abnormal lacrimal gland morphology |
435 |
MGI:1929915 |
605299 |
56406  |
Ncoa6 | nuclear receptor coactivator 6 |
abnormal eye pigmentation |
436 |
MGI:1891700 |
605254 |
59287  |
Ncstn | nicastrin |
abnormal optic vesicle formation |
437 |
MGI:102570 |
|
  |
Ndp | Norrie disease (pseudoglioma) (human) |
decreased retinal photoreceptor cell numberdisorganized retinal layersabnormal vitreous bodyabnormal retinal vasculatureabnormal retinal photoreceptor layerabnormal retinal outer nuclear layer morphologyabnormal retinal outer plexiform layer morphologyabnormal retinal inner nuclear layer morphologyabnormal retinal pigmentationvitreous body depositiondisorganized retinal ganglion layerphotoreceptor outer segment degeneration |
438 |
MGI:104719 |
600853 |
15531  |
Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
abnormal eye developmentanophthalmiamicrophthalmiaabnormal eye morphologyaphakiacoloboma |
439 |
MGI:1343135 |
602694 |
17993  |
Ndufs4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4 |
cataractsblindnessabnormal eye electrophysiology |
440 |
MGI:97292 |
161650 |
17996  |
Neb | nebulin |
blepharoptosis |
441 |
MGI:97305 |
608272 |
18010  |
Neu1 | neuraminidase 1 |
eyelid edema |
442 |
MGI:1339708 |
601724 |
18012  |
Neurod1 | neurogenic differentiation 1 |
abnormal amacrine cell morphologyabnormal Muller cell morphologyabnormal retinal apoptosisabnormal retinal bipolar cell morphology |
443 |
MGI:108055 |
611635 |
11923  |
Neurod4 | neurogenic differentiation 4 |
abnormal optic nerve morphologyincreased retinal ganglion cell numberabnormal retinal ganglion layer morphologyabnormal Muller cell morphologyabsent amacrine cellsabsent retinal bipolar cells |
444 |
MGI:97306 |
162200 |
18015  |
Nf1 | neurofibromatosis 1 |
microphthalmiareduced eye pigmentation |
445 |
MGI:102463 |
600490 |
18019  |
Nfatc2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
blepharitis |
446 |
MGI:103296 |
602698 |
18021  |
Nfatc3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
periorbital edema |
447 |
MGI:103188 |
600728 |
18028  |
Nfib | nuclear factor I/B |
eyelids open at birth |
448 |
MGI:97311 |
164005 |
18032  |
Nfix | nuclear factor I/X |
delayed eyelid openingabnormal timing of postnatal eyelid opening |
449 |
MGI:1931595 |
608004 |
80859  |
Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
abnormal eyelid morphologyabnormal conjunctival epithelium |
450 |
MGI:97321 |
162030 |
18049  |
Ngf | nerve growth factor |
delayed eyelid openingblepharoptosis |
451 |
MGI:97323 |
162010 |
18053  |
Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) |
increased retinal photoreceptor cell number |
452 |
MGI:2684894 |
300457 |
195727  |
Nhs | Nance-Horan syndrome (human) |
abnormal lens morphologycataractsabnormal lens fiber morphologyabnormal lens capsule morphologyabnormal lens developmentruptured lens capsule |
453 |
MGI:1352738 |
605955 |
14912  |
Nkx6-2 | NK6 homeobox 2 |
abnormal optic nerve morphology |
454 |
MGI:2683163 |
|
  |
Nmf128 | neuroscience mutagenesis facility, 128 |
corneal scarringabnormal retina morphologyabnormal vitreous body |
455 |
MGI:3511213 |
|
  |
Nmf191 | neuroscience mutagenesis facility, 191 |
abnormal retina morphology |
456 |
MGI:3038636 |
|
  |
Nmf193 | neuroscience mutagenesis facility, 193 |
abnormal retina morphology |
457 |
MGI:104327 |
602991 |
18121  |
Nog | noggin |
abnormal eye developmentanophthalmiacyclopia |
458 |
MGI:97360 |
163731 |
18125  |
Nos1 | nitric oxide synthase 1, neuronal |
choroidal neovascularization |
459 |
MGI:97361 |
163730 |
18126  |
Nos2 | nitric oxide synthase 2, inducible |
choroidal neovascularization |
460 |
MGI:97364 |
600275 |
18129  |
Notch2 | Notch gene homolog 2 (Drosophila) |
abnormal eye developmentmicrophthalmiaabnormal eye morphology |
461 |
MGI:109185 |
164958 |
18133  |
Nov | nephroblastoma overexpressed gene |
cataracts |
462 |
MGI:106184 |
164040 |
18148  |
Npm1 | nucleophosmin 1 |
abnormal eye developmentanophthalmia |
463 |
MGI:107811 |
602367 |
18164  |
Nptx1 | neuronal pentraxin 1 |
abnormal eye electrophysiology |
464 |
MGI:1100526 |
603849 |
21907  |
Nr2e1 | nuclear receptor subfamily 2, group E, member 1 |
persistence of hyaloid capillary systemabnormal retina morphologyabnormal optic nerve morphologyabnormal retinal vasculatureabnormal retinal photoreceptor layerabnormal retinal inner plexiform layer morphologyabnormal retinal ganglion layer morphologyabnormal eye electrophysiologyabnormal retinal nerve fiber layer morphologythin retinal inner nuclear layer |
465 |
MGI:1346317 |
604485 |
23958  |
Nr2e3 | nuclear receptor subfamily 2, group E, member 3 |
abnormal retinal photoreceptor morphologyabnormal retinal cone cell morphologyretinal degenerationabnormal retinal outer nuclear layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiology |
466 |
MGI:104750 |
601581 |
319504  |
Nrcam | neuron-glia-CAM-related cell adhesion molecule |
cataractsdisorganized secondary lens fibers |
467 |
MGI:102567 |
162080 |
18185  |
Nrl | neural retina leucine zipper gene |
abnormal retinal photoreceptor morphologyabnormal photoreceptor outer segment morphologyabnormal retinal outer nuclear layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiology |
468 |
MGI:108417 |
602018 |
18188  |
Nrtn | neurturin |
abnormal eye distance/ positionincreased incidence of corneal inflammationdry eyesblepharoptosisabnormal lacrimal gland physiologyabnormal eye morphologyabnormal eye physiologyabnormal corneal epithelium morphology |
469 |
MGI:1099438 |
300275 |
18194  |
Nsdhl | NAD(P) dependent steroid dehydrogenase-like |
cataracts |
470 |
MGI:97383 |
191315 |
18211  |
Ntrk1 | neurotrophic tyrosine kinase, receptor, type 1 |
corneal opacityblepharoptosismiotic pupils |
471 |
MGI:97384 |
600456 |
18212  |
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 |
abnormal eye developmentabnormal rod electrophysiologydecreased retinal ganglion cell numberabnormal retinal ganglion cell morphologyabnormal retinal rod cell outer segment morphology |
472 |
MGI:97387 |
|
104352  |
Nuca | dominant nuclear cataract |
cataracts |
473 |
MGI:2448607 |
300278 |
236690  |
Nyx | nyctalopin |
abnormal visionabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye electrophysiology |
474 |
MGI:97394 |
258870 |
18242  |
Oat | ornithine aminotransferase |
abnormal retina morphologyretinal degenerationdecreased retinal photoreceptor cell numberabnormal retinal pigment epithelium morphologyabnormal eye electrophysiologythin retinal outer nuclear layerdisorganized photoreceptor inner segmentshort photoreceptor inner segmentabsent photoreceptor outer segmentshort photoreceptor outer segment |
475 |
MGI:97454 |
611409 |
18431  |
Oca2 | oculocutaneous albinism II |
abnormal eye pigmentationreduced eye pigmentationocular albinism |
476 |
MGI:1890407 |
|
110459  |
Ods | ocular degeneration with sex reversal |
abnormal eye developmentmicrophthalmiacataracts |
477 |
MGI:109278 |
602383 |
18295  |
Ogn | osteoglycin |
abnormal cornea morphology |
478 |
MGI:1921393 |
605290 |
74143  |
Opa1 | optic atrophy 1 homolog (human) |
abnormal optic nerve morphologyabnormal vision |
479 |
MGI:1934619 |
|
207129  |
Opdc | optic disc coloboma |
abnormal optic nerve morphologyabnormal eye morphologycoloboma |
480 |
MGI:1097692 |
303800 |
14539  |
Opn1mw | opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) |
abnormal vision |
481 |
MGI:1353425 |
606665 |
30044  |
Opn4 | opsin 4 (melanopsin) |
photosensitivityabnormal pupillary reflexabnormal visual pursuitimpaired pupilary reflexabnormal retinal ganglion cell morphology |
482 |
MGI:1925542 |
610277 |
109305  |
Orai1 | ORAI calcium release-activated calcium modulator 1 |
blepharitis |
483 |
MGI:1930813 |
611297 |
107587  |
Osr2 | odd-skipped related 2 (Drosophila) |
eyelids open at birth |
484 |
MGI:2655574 |
607649 |
14628  |
Ostm1 | osteopetrosis associated transmembrane protein 1 |
delayed eyelid openingeye inflammation |
485 |
MGI:97450 |
600036 |
18423  |
Otx1 | orthodenticle homolog 1 (Drosophila) |
abnormal lens morphologyabnormal cornea morphologyabnormal iris morphologyretina hyperplasiaabnormal optic nerve morphologyabnormal lacrimal gland morphologyabsent lacrimal glandsabnormal eye anterior chamberabsent Harderian gland |
486 |
MGI:97451 |
600037 |
18424  |
Otx2 | orthodenticle homolog 2 (Drosophila) |
abnormal eye developmentanophthalmiamicrophthalmiaabnormal eye distance/ positionabnormal cornea morphologyabnormal iris morphologyabnormal eyelid morphologyabnormal eye morphologyabnormal sclera morphologyaphakiaabnormal retinal layer morphologyabnormal anterior eye segment morphologyabnormal extraocular muscle morphologyretinal pigment epithelium hyperplasiaabsent optic vesicle |
487 |
MGI:1338039 |
|
107586  |
Ovol2 | ovo-like 2 (Drosophila) |
abnormal eye development |
488 |
MGI:1921700 |
606157 |
74450  |
Pank2 | pantothenate kinase 2 (Hallervorden-Spatz syndrome) |
retinal degenerationabnormal pupillary reflexabnormal retinal outer nuclear layer morphologyabnormal retinal rod cell inner segment morphologyabnormal retinal rod cell outer segment morphology |
489 |
MGI:97486 |
167409 |
18504  |
Pax2 | paired box gene 2 |
abnormal eye developmentabnormal retina morphologyabnormal optic nerve morphologyabnormal optic nerve innervationabnormal optic stalk morphologyabnormal optic cup morphologyabnormal retinal pigmentationcoloboma |
490 |
MGI:97490 |
607108 |
18508  |
Pax6 | paired box gene 6 |
abnormal eye developmentabnormal lens inductionabnormal lens vesicle developmentanophthalmiamicrophthalmiaabnormal lens morphologycataractssmall lensfused cornea and lensabnormal cornea morphologycorneal opacityabnormal pupil morphologyirregularly shaped pupillarge pupilsabnormal iris morphologyabnormal retina morphologyabnormal optic nerve morphologyabnormal eyelid morphologyabnormal eye morphologyabnormal vitreous bodyabnormal lens fiber morphologyaphakiaabnormal anterior stroma morphologyabnormal lens epithelium morphologyabnormal optic vesicle formationabnormal retinal photoreceptor layerabnormal iridocorneal angleabnormal optic cup morphologyreduced eye pigmentationabnormal anterior eye segment morphologyabnormal retinal pigment epithelium morphologyabnormal eye anterior chamberabnormal retinal ganglion layer morphologyaniridiacolobomaabnormal corneal stroma morphologyabnormal corneal endothelium morphologycorneal vascularizationabnormal lens developmentabnormal corneal epithelium morphologyiris hypoplasiacorneal adhesion to irisabnormal Bowman membrane |
491 |
MGI:94873 |
126090 |
13180  |
Pcbd1 | pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 |
microphthalmiacataracts |
492 |
MGI:2157782 |
609502 |
170677  |
Pcdh21 | protocadherin 21 |
abnormal retina morphologyretinal degenerationabnormal eye electrophysiology |
493 |
MGI:102897 |
167405 |
18553  |
Pcsk6 | proprotein convertase subtilisin/kexin type 6 |
cyclopia |
494 |
MGI:98090 |
171490 |
20028  |
Pdc | phosducin |
abnormal eye physiology |
495 |
MGI:104879 |
600244 |
18566  |
Pdcd1 | programmed cell death 1 |
exophthalmos |
496 |
MGI:97525 |
180072 |
18587  |
Pde6b | phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide |
abnormal retinal rod cell morphologyabnormal retina morphologyretinal degenerationabnormal eye morphologyabnormal retinal vasculatureabnormal photoreceptor outer segment morphologyabnormal retinal outer nuclear layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal Muller cell morphologyabnormal eye electrophysiologyimpaired pupilary reflexdecreased retinal cone cell numberretinal rod cell degenerationabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layerretinal outer nuclear layer degenerationabsent photoreceptor outer segment |
497 |
MGI:105956 |
600827 |
110855  |
Pde6c | phosphodiesterase 6C, cGMP specific, cone, alpha prime |
abnormal cone electrophysiologyretinal cone cell degenerationdecreased retinal cone cell number |
498 |
MGI:97528 |
190040 |
18591  |
Pdgfb | platelet derived growth factor, B polypeptide |
microphthalmiaabnormal retina morphologyretinal degenerationabnormal eye morphologyabnormal retinal vasculatureabnormal retinal photoreceptor layerabnormal retinal pigment epithelium morphologyabnormal retinal neuronal layer morphologyretinal fibrosis |
499 |
MGI:1859631 |
608452 |
54635  |
Pdgfc | platelet-derived growth factor, C polypeptide |
abnormal retinal pigmentation |
500 |
MGI:97531 |
173410 |
18596  |
Pdgfrb | platelet derived growth factor receptor, beta polypeptide |
abnormal eye morphologyabnormal retinal vasculatureretinal detachmentretinal hemorrhage |
501 |
MGI:1338068 |
605213 |
18607  |
Pdpk1 | 3-phosphoinositide dependent protein kinase-1 |
abnormal eye pigmentation |
502 |
MGI:1321392 |
601757 |
18634  |
Pex7 | peroxisome biogenesis factor 7 |
cataracts |
503 |
MGI:105095 |
601121 |
18654  |
Pgf | placental growth factor |
corneal vascularization |
504 |
MGI:2140327 |
608726 |
100169  |
Phactr4 | phosphatase and actin regulator 4 |
abnormal retina morphologyabnormal retinal pigment epithelium morphologycolobomaabnormal retinal neuronal layer morphology |
505 |
MGI:103248 |
|
13619  |
Phc1 | polyhomeotic-like 1 (Drosophila) |
abnormal eye development |
506 |
MGI:1100882 |
603851 |
18935  |
Phox2b | paired-like homeobox 2b |
abnormal eye morphologymydriasisimpaired pupilary reflex |
507 |
MGI:1206581 |
171834 |
18706  |
Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide |
abnormal retinal vasculature |
508 |
MGI:1346036 |
601052 |
23988  |
Pin1 | protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 |
retinal degeneration |
509 |
MGI:109340 |
601542 |
18741  |
Pitx2 | paired-like homeodomain transcription factor 2 |
abnormal eye developmentmicrophthalmiaabnormal lens morphologycataractsabnormal cornea morphologyabnormal pupil morphologyirregularly shaped pupilabnormal eye morphologyabnormal eye muscle morphologyabnormal eye muscle developmentabsent corneal endotheliumabnormal eye anterior chamberabnormal orbit morphologyabnormal extraocular muscle morphologyabnormal lens developmentabnormal corneal epithelium morphologyenophthalmosanisocoriaabnormal placement of pupils |
510 |
MGI:1100498 |
602669 |
18742  |
Pitx3 | paired-like homeodomain transcription factor 3 |
microphthalmiaabnormal eye distance/ positionabnormal pupil morphologyabnormal retina morphologyabnormal lacrimal gland morphologyabnormal eye morphologyabnormal ocular fundus morphologyabnormal iris pigmentationabnormal anterior eye segment morphologyabnormal posterior eye segment morphologyabnormal lens development |
511 |
MGI:1891916 |
603026 |
56711  |
Plag1 | pleiomorphic adenoma gene 1 |
delayed eyelid opening |
512 |
MGI:97610 |
173370 |
18791  |
Plat | plasminogen activator, tissue |
abnormal eyelid morphologyresistance to induced choroidal neovascularizationresistance to induced retinal damageabnormal retinal apoptosis |
513 |
MGI:97611 |
191840 |
18792  |
Plau | plasminogen activator, urokinase |
abnormal eyelid morphologyresistance to induced choroidal neovascularization |
514 |
MGI:97612 |
173391 |
18793  |
Plaur | plasminogen activator, urokinase receptor |
choroidal neovascularization |
515 |
MGI:107464 |
600810 |
18798  |
Plcb4 | phospholipase C, beta 4 |
abnormal visionabnormal rod electrophysiology |
516 |
MGI:1927580 |
604310 |
18457  |
Pldn | pallidin |
reduced eye pigmentation |
517 |
MGI:97620 |
173350 |
18815  |
Plg | plasminogen |
abnormal conjunctiva morphologyabnormal cornea morphologyeye inflammationconjunctivitisabnormal conjunctival epitheliumabnormal choroid morphologyabnormal corneal stroma morphologycorneal vascularizationabnormal corneal epithelium morphologyectropion |
518 |
MGI:1099790 |
607023 |
20620  |
Plk2 | polo-like kinase 2 (Drosophila) |
eyelids open at birth |
519 |
MGI:97623 |
300401 |
18823  |
Plp1 | proteolipid protein (myelin) 1 |
abnormal optic nerve morphology |
520 |
MGI:1915523 |
606822 |
68273  |
Pomgnt1 | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase |
abnormal optic nerve morphologyabnormal retinal layer morphologyabnormal eye electrophysiologydecreased retinal ganglion cell numberthin retinal inner nuclear layerthin retinal outer nuclear layer |
521 |
MGI:97744 |
124015 |
18984  |
Por | P450 (cytochrome) oxidoreductase |
abnormal eye morphology |
522 |
MGI:101898 |
164175 |
18986  |
Pou2f1 | POU domain, class 2, transcription factor 1 |
abnormal eye developmentabnormal lens inductionanophthalmiamicrophthalmiaabnormal lens morphologysmall lens |
523 |
MGI:102524 |
|
18997  |
Pou4f2 | POU domain, class 4, transcription factor 2 |
abnormal retina morphologyabnormal optic nerve morphologyabnormal optic nerve innervationabnormal retinal apoptosisabnormal retinal nerve fiber layer morphologydecreased retinal ganglion cell numberabnormal retinal ganglion cell morphologyretinal ganglion cell degenerationincreased amacrine cell numberthin retinal ganglion layer |
524 |
MGI:102523 |
602460 |
18998  |
Pou4f3 | POU domain, class 4, transcription factor 3 |
abnormal retina morphologyabnormal retinal nerve fiber layer morphologydecreased retinal ganglion cell numberabnormal retinal ganglion cell morphologyincreased amacrine cell numberthin retinal ganglion layer |
525 |
MGI:3665245 |
|
  |
Ppd | polypodia |
microphthalmia |
526 |
MGI:97749 |
123840 |
268373  |
Ppia | peptidylprolyl isomerase A |
blepharitis |
527 |
MGI:3525053 |
607463 |
333654  |
Ppp1r13l | protein phosphatase 1, regulatory (inhibitor) subunit 13 like |
eyelids open at birth |
528 |
MGI:1298204 |
600722 |
19063  |
Ppt1 | palmitoyl-protein thioesterase 1 |
blindnessabnormal retinal neuronal layer morphology |
529 |
MGI:97772 |
601546 |
19130  |
Prox1 | prospero-related homeobox 1 |
abnormal eye developmentabnormal lens morphologyabnormal retina morphologyabnormal lens developmentabsent horizontal cells |
530 |
MGI:102791 |
179605 |
19133  |
Prph2 | peripherin 2 |
abnormal retinal photoreceptor morphologyabnormal eye developmentretinal degenerationabnormal retinal layer morphologyabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal pigment epithelium morphologyabnormal Muller cell morphologyincreased retinal cone cell numberretinal photoreceptor degenerationabsent retinal rod cellsthin retinal outer nuclear layerretinal outer nuclear layer degenerationabsent photoreceptor outer segment |
531 |
MGI:97712 |
167420 |
18933  |
Prrx1 | paired related homeobox 1 |
eyelids open at birthabsent eyelids |
532 |
MGI:97783 |
176801 |
19156  |
Psap | prosaposin |
abnormal eye morphologyabnormal corneal stroma morphology |
533 |
MGI:109284 |
600759 |
19165  |
Psen2 | presenilin 2 |
increased incidence of corneal inflammationabnormal corneal epithelium morphology |
534 |
MGI:2142116 |
603620 |
101739  |
Psip1 | PC4 and SFRS1 interacting protein 1 |
blepharitis |
535 |
MGI:105373 |
601309 |
19206  |
Ptch1 | patched homolog 1 |
anophthalmia |
536 |
MGI:1328312 |
607194 |
19213  |
Ptf1a | pancreas specific transcription factor, 1a |
abnormal eye developmentabnormal retina morphologyincreased retinal ganglion cell numberabsent amacrine cellsabsent horizontal cellsthick retinal ganglion layerabsent retinal inner plexiform layer |
537 |
MGI:97806 |
176887 |
19255  |
Ptpn2 | protein tyrosine phosphatase, non-receptor type 2 |
narrow eye opening |
538 |
MGI:1926483 |
600644 |
58235  |
Pvrl1 | poliovirus receptor-related 1 |
microphthalmiaeyelids open at birthabnormal lens morphologyabnormal eyelid morphologyabnormal vitreous bodyabnormal retinal layer morphologyabnormal ciliary body morphologyabnormal anterior eye segment morphology |
539 |
MGI:1930171 |
607147 |
58998  |
Pvrl3 | poliovirus receptor-related 3 |
microphthalmiaabnormal lens morphologyabnormal vitreous bodyabnormal retinal layer morphologyabnormal ciliary body morphologyabnormal anterior eye segment morphology |
540 |
MGI:1916161 |
606903 |
68911  |
Pygo2 | pygopus 2 |
delayed eyelid openingmicrophthalmiasmall lensabnormal cornea morphologyabnormal retina morphologyabnormal lens fiber morphologyaphakiaabnormal lens epithelium morphologyabnormal optic cup morphologyabnormal lens development |
541 |
MGI:99833 |
606144 |
19335  |
Rab23 | RAB23, member RAS oncogene family |
abnormal eye morphology |
542 |
MGI:1919683 |
606281 |
72433  |
Rab38 | Rab38, member of RAS oncogene family |
abnormal eye pigmentation |
543 |
MGI:105128 |
600062 |
19359  |
Rad23b | RAD23b homolog (S. cerevisiae) |
eyelids open at birthconjunctivitisabnormal eye morphologyblepharitis |
544 |
MGI:97847 |
164760 |
110157  |
Raf1 | v-raf-leukemia viral oncogene 1 |
eyelids open at birthabnormal retina morphology |
545 |
MGI:894323 |
601181 |
19386  |
Ranbp2 | RAN binding protein 2 |
abnormal rod electrophysiology |
546 |
MGI:97856 |
180240 |
19401  |
Rara | retinoic acid receptor, alpha |
abnormal vitreous bodyabnormal Harderian gland morphologynarrow eye opening |
547 |
MGI:97857 |
180220 |
218772  |
Rarb | retinoic acid receptor, beta |
persistence of hyaloid capillary systemabnormal lens morphologycataractsabnormal conjunctiva morphologyabnormal retina morphologyabnormal lacrimal gland morphologyabnormal sclera morphologyabnormal vitreous bodyabnormal lens fiber morphologyabnormal eye anterior chamberabnormal iris stroma morphologycolobomanarrow eye openingabnormal corneal stroma morphologyabnormal retinal neuronal layer morphologyvitreous body depositionabsent retinal inner plexiform layerabsent Harderian gland |
548 |
MGI:97858 |
180190 |
19411  |
Rarg | retinoic acid receptor, gamma |
abnormal anterior eye segment morphologyabnormal Harderian gland morphologynarrow eye opening |
549 |
MGI:109632 |
601881 |
19434  |
Rax | retina and anterior neural fold homeobox |
abnormal eye developmentanophthalmiamicrophthalmiaabnormal lens morphologysmall lensabnormal optic nerve morphologyabnormal eye morphologyabnormal optic cup morphologyabnormal lens development |
550 |
MGI:97874 |
180200 |
19645  |
Rb1 | retinoblastoma 1 |
abnormal lens fiber morphologyabnormal lens developmentabnormal retinal apoptosisincreased lens fiber apoptosis |
551 |
MGI:103300 |
116957 |
19650  |
Rbl1 | retinoblastoma-like 1 (p107) |
abnormal retinal photoreceptor morphologyabnormal eye developmentabnormal retina morphologydecreased retinal photoreceptor cell numberabnormal optic nerve morphologyabnormal retinal inner nuclear layer morphologyabnormal retinal inner plexiform layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye anterior chamberabnormal amacrine cell morphologyabnormal eye posterior chamberabnormal retinal apoptosisabnormal retinal bipolar cell morphologydecreased retinal ganglion cell numberdecreased retinal rod cell numberthin retinal outer nuclear layer |
552 |
MGI:105085 |
180203 |
19651  |
Rbl2 | retinoblastoma-like 2 |
abnormal retina morphologyretina hypoplasiaabnormal amacrine cell morphologyabnormal horizontal cell morphologyabnormal retinal neuronal layer morphologyabnormal retinal apoptosisabsent retinal bipolar cellsabsent retinal ganglion celldecreased retinal cone cell number |
553 |
MGI:97876 |
180260 |
19659  |
Rbp1 | retinol binding protein 1, cellular |
abnormal retina morphologydelayed dark adaptationabnormal photoreceptor outer segment morphologyabnormal retinal pigment epithelium morphologyabnormal eye physiologyabnormal eye electrophysiology |
554 |
MGI:97878 |
180290 |
19661  |
Rbp3 | retinol binding protein 3, interstitial |
abnormal photoreceptor outer segment morphologyabnormal eye electrophysiologyretinal photoreceptor degenerationthin retinal outer nuclear layershort photoreceptor outer segment |
555 |
MGI:97879 |
180250 |
19662  |
Rbp4 | retinol binding protein 4, plasma |
photosensitivity |
556 |
MGI:97883 |
179618 |
19674  |
Rcvrn | recoverin |
abnormal eye physiologyabnormal eye electrophysiology |
557 |
MGI:1921273 |
180040 |
  |
Rd3 | retinal degeneration 3 |
retinal degenerationabnormal retinal photoreceptor layerabnormal eye electrophysiologyretinal photoreceptor degenerationabsent retinal rod cellsthin retinal outer nuclear layer |
558 |
MGI:3511471 |
|
  |
Rd9 | retinal degeneration 9 |
abnormal retina morphologyabnormal ocular fundus morphologyretinal outer nuclear layer degeneration |
559 |
MGI:102581 |
607849 |
17252  |
Rdh11 | retinol dehydrogenase 11 |
delayed dark adaptationabnormal eye electrophysiology |
560 |
MGI:1925224 |
608830 |
77974  |
Rdh12 | retinol dehydrogenase 12 |
delayed dark adaptationabnormal eye physiologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyabnormal retinal apoptosisabnormal retinal rod cell outer segment morphology |
561 |
MGI:1201412 |
601617 |
19682  |
Rdh5 | retinol dehydrogenase 5 |
delayed dark adaptationabnormal eye electrophysiology |
562 |
MGI:2685028 |
608575 |
235033  |
Rdh8 | retinol dehydrogenase 8 |
delayed dark adaptation |
563 |
MGI:103290 |
164014 |
19697  |
Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
abnormal eye developmentanophthalmiamicrophthalmiablindness |
564 |
MGI:103022 |
600514 |
19699  |
Reln | reelin |
abnormal retinal inner nuclear layer morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal retinal rod bipolar cell morphology |
565 |
MGI:2683486 |
605226 |
68703  |
Rere | arginine glutamic acid dipeptide (RE) repeats |
abnormal optic vesicle formation |
566 |
MGI:1929473 |
600342 |
57811  |
Rgr | retinal G protein coupled receptor |
abnormal eye physiologyabnormal eye electrophysiology |
567 |
MGI:1338824 |
604067 |
19739  |
Rgs9 | regulator of G-protein signaling 9 |
abnormal eye physiology |
568 |
MGI:2384418 |
607814 |
243923  |
Rgs9bp | regulator of G-protein signalling 9 binding protein |
abnormal eye physiology |
569 |
MGI:3808781 |
|
  |
Rgsc1056 | RIKEN Genomic Sciences Center (GSC), 1056 |
abnormal retinal vasculature |
570 |
MGI:3809293 |
|
  |
Rgsc1159 | RIKEN Genomic Sciences Center (GSC), 1159 |
microphthalmiacorneal opacity |
571 |
MGI:3811748 |
|
  |
Rgsc1371 | RIKEN Genomic Sciences Center (GSC), 1371 |
microphthalmiacataractscorneal opacity |
572 |
MGI:3811753 |
|
  |
Rgsc1465 | RIKEN Genomic Sciences Center (GSC), 1465 |
microphthalmiacataractscorneal opacity |
573 |
MGI:3799171 |
|
  |
Rgsc258 | RIKEN Genomic Sciences Center, 258 |
microphthalmiacataracts |
574 |
MGI:3800208 |
|
  |
Rgsc300 | RIKEN Genomic Sciences Center, 300 |
microphthalmia |
575 |
MGI:3808804 |
|
  |
Rgsc301 | RIKEN Genomic Sciences Center (GSC), 301 |
microphthalmia |
576 |
MGI:3808139 |
|
  |
Rgsc400 | RIKEN Genomic Sciences Center (GSC), 400 |
cataracts |
577 |
MGI:3808146 |
|
  |
Rgsc435 | RIKEN Genomic Sciences Center (GSC), 435 |
cataracts |
578 |
MGI:3808897 |
|
  |
Rgsc657 | RIKEN Genomic Sciences Center (GSC), 657 |
microphthalmiacorneal opacity |
579 |
MGI:3808994 |
|
  |
Rgsc834 | RIKEN Genomic Sciences Center (GSC), 834 |
microphthalmiacorneal opacity |
580 |
MGI:3813537 |
|
  |
Rgsc921 | RIKEN Genomic Sciences Center (GSC), 921 |
abnormal ocular fundus morphology |
581 |
MGI:3811740 |
|
  |
Rgsc975 | RIKEN Genomic Sciences Center (GSC), 975 |
cataracts |
582 |
MGI:3809019 |
|
  |
Rgsc976 | RIKEN Genomic Sciences Center (GSC), 976 |
microphthalmiacorneal opacity |
583 |
MGI:3808774 |
|
  |
Rgsc992 | RIKEN Genomic Sciences Center (GSC), 992 |
abnormal retinal vasculature |
584 |
MGI:97914 |
180380 |
212541  |
Rho | rhodopsin |
abnormal eye developmentretinal degenerationdisorganized retinal layersphotosensitivityabnormal visionabnormal retinal outer nuclear layer morphologyabnormal rod electrophysiologyabnormal eye electrophysiologyretinal photoreceptor degenerationdecreased retinal rod cell numberabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layerretinal outer nuclear layer degenerationabsent photoreceptor outer segmentshort photoreceptor outer segment |
585 |
MGI:107949 |
165370 |
11852  |
Rhob | ras homolog gene family, member B |
abnormal retinal vasculature |
586 |
MGI:3662924 |
|
  |
Rky | rocky |
abnormal eye morphology |
587 |
MGI:97930 |
180090 |
19771  |
Rlbp1 | retinaldehyde binding protein 1 |
retinal degenerationdecreased retinal photoreceptor cell numberdelayed dark adaptationabnormal eye physiology |
588 |
MGI:107927 |
601702 |
19877  |
Rock1 | Rho-associated coiled-coil containing protein kinase 1 |
eyelids open at birthabnormal eyelid morphologyblepharitis |
589 |
MGI:97998 |
180721 |
19881  |
Rom1 | rod outer segment membrane protein 1 |
abnormal retina morphologyabnormal rod electrophysiologyretinal rod cell degenerationabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layer |
590 |
MGI:1347521 |
602337 |
26564  |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 |
excessive tearingentropionabnormal orbit size |
591 |
MGI:1343464 |
601972 |
225998  |
Rorb | RAR-related orphan receptor beta |
abnormal retina morphologyretinal degenerationdisorganized retinal layersabnormal eye physiology |
592 |
MGI:1341105 |
603937 |
19888  |
Rp1h | retinitis pigmentosa 1 homolog (human) |
abnormal retinal photoreceptor morphologyretinal degenerationdecreased retinal photoreceptor cell numberabnormal ocular fundus morphologyabnormal photoreceptor outer segment morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal eye physiologyretinal cone cell degenerationthin retinal outer nuclear layer |
593 |
MGI:98001 |
180069 |
19892  |
Rpe65 | retinal pigment epithelium 65 |
retinal degenerationdelayed dark adaptationabnormal photoreceptor outer segment morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal retinal pigment epithelium morphologyabnormal eye physiologyabnormal eye electrophysiologyretinal rod cell degenerationabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layerretinal outer nuclear layer degenerationphotoreceptor outer segment degenerationdisorganized photoreceptor outer segmentshort photoreceptor outer segment |
594 |
MGI:1344037 |
312610 |
19893  |
Rpgr | retinitis pigmentosa GTPase regulator |
abnormal retinal cone cell morphologyabnormal retina morphologyretinal degenerationabnormal eye physiologyretinal cone cell degenerationretinal photoreceptor degenerationretinal rod cell degenerationabnormal retinal rod cell outer segment morphologythin retinal outer nuclear layershort photoreceptor outer segment |
595 |
MGI:1932134 |
605446 |
77945  |
Rpgrip1 | retinitis pigmentosa GTPase regulator interacting protein 1 |
abnormal photoreceptor outer segment morphologyabnormal rod electrophysiologyabnormal cone electrophysiologyretinal photoreceptor degeneration |
596 |
MGI:1920563 |
610937 |
244585  |
Rpgrip1l | Rpgrip1-like |
anophthalmiamicrophthalmia |
597 |
MGI:1915443 |
604180 |
68193  |
Rpl24 | ribosomal protein L24 |
abnormal eye developmentpersistence of hyaloid capillary systemcataractsabnormal retina morphologyabnormal optic nerve morphologyabsent optic nerveabnormal eye morphologyabnormal retinal vasculatureretina hypoplasiaretinal detachmentabnormal retinal inner plexiform layer morphologyabnormal optic cup morphologyabnormal choroid morphologyabnormal retinal ganglion layer morphologycolobomaabnormal retinal neuronal layer morphologyabnormal retinal progenitor morphologyasymmetrical orbitsoptic nerve hypoplasiaimpaired pupilary reflexthin retinal ganglion layerthin retinal inner nuclear layerdisorganized retinal inner nuclear layerdisorganized retinal outer nuclear layer |
598 |
MGI:1336189 |
312700 |
20147  |
Rs1 | retinoschisis (X-linked, juvenile) 1 (human) |
abnormal retinal photoreceptor morphologyabnormal retina morphologydisorganized retinal layersabnormal ocular fundus morphologyabnormal retinal photoreceptor layerabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal outer nuclear layer morphologyabnormal retinal outer plexiform layer morphologyabnormal retinal inner nuclear layer morphologyabnormal cone electrophysiologyabnormal retinal pigment epithelium morphologyabnormal amacrine cell morphologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologydecreased retinal cone cell numberdisorganized retinal inner nuclear layerdisorganized retinal outer nuclear layerabsent photoreceptor outer segment |
599 |
MGI:99829 |
600211 |
12393  |
Runx2 | runt related transcription factor 2 |
eyelids open at birth |
600 |
MGI:1934624 |
|
245707  |
Rvm | retinal vascular mass |
abnormal retinal vasculaturecoloboma |
601 |
MGI:1890529 |
|
207128  |
Rwhs | retinal white spots |
abnormal retina morphologydisorganized retinal layers |
602 |
MGI:98214 |
180245 |
20181  |
Rxra | retinoid X receptor alpha |
corneal opacityabnormal eye morphology |
603 |
MGI:1929059 |
607535 |
56353  |
Rybp | RING1 and YY1 binding protein |
optic nerve atrophyabnormal lens polarityretina hyperplasiacoloboma |
604 |
MGI:101766 |
600524 |
20187  |
Ryk | receptor-like tyrosine kinase |
microphthalmia |
605 |
MGI:105084 |
602075 |
20230  |
Satb1 | special AT-rich sequence binding protein 1 |
delayed eyelid opening |
606 |
MGI:1927144 |
607203 |
64010  |
Sav1 | salvador homolog 1 (Drosophila) |
retina hyperplasia |
607 |
MGI:98239 |
|
20249  |
Scd1 | stearoyl-Coenzyme A desaturase 1 |
meibomian gland atrophyblindnesseyelids fail to openabnormal meibomian gland morphologyabnormal eye physiologynarrow eye opening |
608 |
MGI:98247 |
600235 |
20266  |
Scn1b | sodium channel, voltage-gated, type I, beta |
abnormal optic nerve morphology |
609 |
MGI:2145950 |
607733 |
105782  |
Scrib | scribbled homolog (Drosophila) |
microphthalmiaabnormal retina morphologyabnormal optic nerve innervationabsent eyelidsabnormal retinal ganglion layer morphology |
610 |
MGI:1931787 |
607982 |
78891  |
Scyl1 | SCY1-like 1 (S. cerevisiae) |
abnormal optic nerve morphology |
611 |
MGI:98278 |
131210 |
20339  |
Sele | selectin, endothelial cell |
eye inflammation |
612 |
MGI:98280 |
173610 |
20344  |
Selp | selectin, platelet |
eye inflammation |
613 |
MGI:1340034 |
608166 |
20349  |
Sema3e | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
abnormal optic disc morphology |
614 |
MGI:107560 |
607292 |
20351  |
Sema4a | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
retinal degenerationdecreased retinal photoreceptor cell numberabnormal eye morphologyabnormal photoreceptor outer segment morphologyreduced eye pigmentationabnormal retinal pigment epithelium morphologyabnormal eye physiologyabnormal eye electrophysiologyabnormal retinal cone cell outer segment morphologyabnormal retinal rod cell outer segment morphologythin retinal inner nuclear layerthin retinal inner plexiform layerthin retinal outer nuclear layer |
615 |
MGI:88095 |
107300 |
11905  |
Serpinc1 | serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 |
abnormal cornea morphologyabnormal retina morphologyabnormal eye morphologyabnormal sclera morphologyabnormal retinal layer morphologyabnormal choroid morphologyabnormal pigment epithelium of the eye |
616 |
MGI:1891831 |
601290 |
55948  |
Sfn | stratifin |
microphthalmia |
617 |
MGI:98282 |
165170 |
20375  |
Sfpi1 | SFFV proviral integration 1 |
abnormal eye developmentpersistence of hyaloid capillary system |
618 |
MGI:109517 |
178620 |
20389  |
Sftpc | surfactant associated protein C |
conjunctivitis |
619 |
MGI:1350341 |
605270 |
27029  |
Sgsh | N-sulfoglucosamine sulfohydrolase (sulfamidase) |
corneal opacity |
620 |
MGI:1346349 |
602104 |
24055  |
Sh3bp2 | SH3-domain binding protein 2 |
blepharitis |
621 |
MGI:1913331 |
611885 |
106025  |
Sharpin | SHANK-associated RH domain interacting protein |
thick eyelids |
622 |
MGI:98297 |
600725 |
20423  |
Shh | sonic hedgehog |
anophthalmiaabnormal optic vesicle formationcyclopia |
623 |
MGI:98305 |
|
109565  |
Sig | sightless |
eyelids open at birthbinocular blindness |
624 |
MGI:2135607 |
604479 |
93759  |
Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) |
abnormal retinal photoreceptor morphologyabnormal eye developmentmicrophthalmiaabnormal eye morphologyabnormal retinal layer morphologyeyelids fail to opendisorganized retinal inner nuclear layerdisorganized retinal outer nuclear layer |
625 |
MGI:102780 |
601205 |
20471  |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) |
eyelids open at birthabnormal lacrimal gland morphologyexophthalmos |
626 |
MGI:102764 |
603714 |
20473  |
Six3 | sine oculis-related homeobox 3 homolog (Drosophila) |
abnormal lens inductionabnormal lens vesicle developmentabnormal lens morphologycataractssmall lensabnormal lens fiber morphologyaphakiaabnormal optic vesicle formationabnormal lens developmentabsent optic vesicle |
627 |
MGI:106220 |
600963 |
20475  |
Six5 | sine oculis-related homeobox 5 homolog (Drosophila) |
cataracts |
628 |
MGI:1341840 |
606326 |
20476  |
Six6 | sine oculis-related homeobox 6 homolog (Drosophila) |
abnormal retina morphologyabsent optic nerveretina hypoplasiaabnormal retinal ganglion layer morphology |
629 |
MGI:98310 |
164780 |
20481  |
Ski | ski sarcoma viral oncogene homolog (avian) |
eyelids open at birth |
630 |
MGI:2135960 |
604878 |
107723  |
Slc12a6 | solute carrier family 12, member 6 |
abnormal optic stalk morphology |
631 |
MGI:1929519 |
610409 |
57274  |
Slc16a8 | solute carrier family 16 (monocarboxylic acid transporters), member 8 |
abnormal eye electrophysiology |
632 |
MGI:1920211 |
605208 |
72961  |
Slc17a7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 |
blindness |
633 |
MGI:1919277 |
607059 |
72027  |
Slc39a4 | solute carrier family 39 (zinc transporter), member 4 |
anophthalmia |
634 |
MGI:1315204 |
604653 |
53945  |
Slc40a1 | solute carrier family 40 (iron-regulated transporter), member 1 |
microphthalmia |
635 |
MGI:2153040 |
606202 |
22293  |
Slc45a2 | solute carrier family 45, member 2 |
abnormal eye pigmentationreduced eye pigmentation |
636 |
MGI:109350 |
106195 |
20536  |
Slc4a3 | solute carrier family 4 (anion exchanger), member 3 |
abnormal optic nerve morphologyblindnessabnormal retinal vasculatureabnormal eye electrophysiologyabnormal retinal apoptosisabnormal retinal rod bipolar cell morphology |
637 |
MGI:2443878 |
603353 |
218756  |
Slc4a7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
decreased retinal photoreceptor cell numberblindnessabnormal retinal vasculatureabnormal ocular fundus morphologyabnormal rod electrophysiologyabnormal retinal apoptosisretinal photoreceptor degenerationthin retinal outer nuclear layerphotoreceptor outer segment degenerationshort photoreceptor outer segment |
638 |
MGI:98488 |
186854 |
21366  |
Slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 |
retinal degenerationabnormal visionretinal photoreceptor degeneration |
639 |
MGI:108051 |
601366 |
17126  |
Smad2 | MAD homolog 2 (Drosophila) |
abnormal eye developmentabnormal eye morphologycyclopia |
640 |
MGI:1328366 |
601607 |
20587  |
Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
abnormal eye development |
641 |
MGI:1096393 |
602150 |
20583  |
Snai2 | snail homolog 2 (Drosophila) |
abnormal conjunctiva morphologyconjunctivitisblepharitis |
642 |
MGI:104665 |
102642 |
20652  |
Soat1 | sterol O-acyltransferase 1 |
dry eyesmeibomian gland atrophynarrow eye opening |
643 |
MGI:98352 |
147460 |
20656  |
Sod2 | superoxide dismutase 2, mitochondrial |
abnormal retina morphologyabnormal optic nerve morphologyabnormal retinal photoreceptor layerabnormal retinal pigment epithelium morphologythin retinal inner nuclear layer |
644 |
MGI:3717450 |
|
  |
Sofa | short face |
ocular hypertelorism |
645 |
MGI:1338015 |
602458 |
20661  |
Sort1 | sortilin 1 |
abnormal retinal ganglion cell morphology |
646 |
MGI:98357 |
602148 |
20664  |
Sox1 | SRY-box containing gene 1 |
abnormal lens vesicle developmentmicrophthalmiasmall lensabnormal lens development |
647 |
MGI:98359 |
600898 |
20666  |
Sox11 | SRY-box containing gene 11 |
abnormal eyelid morphology |
648 |
MGI:98364 |
184429 |
20674  |
Sox2 | SRY-box containing gene 2 |
anophthalmiamicrophthalmiadisorganized retinal layersretina hyperplasiaoptic nerve hypoplasia |
649 |
MGI:98372 |
189906 |
20683  |
Sp1 | trans-acting transcription factor 1 |
anophthalmia |
650 |
MGI:1277166 |
601804 |
20687  |
Sp3 | trans-acting transcription factor 3 |
anophthalmia |
651 |
MGI:98373 |
182120 |
20692  |
Sparc | secreted acidic cysteine rich glycoprotein |
abnormal lens morphologycataractsretinal degenerationeye inflammationabnormal lens fiber morphologyretinal detachmentabnormal lens capsule morphologyabnormal lens epithelium morphologyabnormal retinal layer morphologyvitreous body inflammationruptured lens capsule |
652 |
MGI:1890574 |
606214 |
80297  |
Spnb4 | spectrin beta 4 |
abnormal optic nerve morphology |
653 |
MGI:1345138 |
602466 |
24064  |
Spry2 | sprouty homolog 2 (Drosophila) |
cyclopia |
654 |
MGI:98397 |
190090 |
20779  |
Src | Rous sarcoma oncogene |
delayed eyelid openingabnormal anterior eye segment morphology |
655 |
MGI:98327 |
182451 |
20605  |
Sstr1 | somatostatin receptor 1 |
abnormal eye electrophysiologyabnormal retinal apoptosisabnormal retinal rod bipolar cell morphology |
656 |
MGI:98328 |
182452 |
20606  |
Sstr2 | somatostatin receptor 2 |
abnormal retinal rod bipolar cell morphology |
657 |
MGI:1917777 |
606247 |
70527  |
Stambp | Stam binding protein |
blepharoptosis |
658 |
MGI:103063 |
600555 |
20846  |
Stat1 | signal transducer and activator of transcription 1 |
abnormal cornea morphology |
659 |
MGI:107476 |
605921 |
20866  |
Stim1 | stromal interaction molecule 1 |
blepharitis |
660 |
MGI:3029925 |
|
  |
Stol | stripy oily |
microphthalmiaabnormal meibomian gland morphology |
661 |
MGI:1919293 |
610013 |
72043  |
Sulf2 | sulfatase 2 |
anophthalmiamicrophthalmia |
662 |
MGI:1277234 |
604127 |
21384  |
Tbx15 | T-box 15 |
ocular hypertelorismabnormal eyelid morphology |
663 |
MGI:104671 |
107580 |
21418  |
Tcfap2a | transcription factor AP-2, alpha |
abnormal lens inductionabnormal lens vesicle developmentanophthalmiaocular hypertelorismabnormal lens morphologysmall lensabnormal cornea morphologyabnormal iris morphologyabnormal retina morphologyabsent eyelidsabnormal choroid morphologyabnormal retinal pigment epithelium morphologyaniridiaabnormal lens developmentabsent retinal ganglion layer |
664 |
MGI:98533 |
|
110289  |
Tcm | total cataract with microphthalmia |
abnormal eye developmentabnormal lens vesicle developmentanophthalmiamicrophthalmiaabnormal lens morphologycataractssmall lenssmall pupilsabnormal iris morphologyabnormal retina morphologyabnormal retinal layer morphologyabnormal optic stalk morphologyabnormal optic cup morphology |
665 |
MGI:892003 |
606847 |
21453  |
Tcof1 | Treacher Collins Franceschetti syndrome 1, homolog |
anophthalmiaabsent optic vesicle |
666 |
MGI:98658 |
187395 |
21667  |
Tdgf1 | teratocarcinoma-derived growth factor 1 |
cyclopia |
667 |
MGI:109558 |
602322 |
21748  |
Terc | telomerase RNA component |
cataracts |
668 |
MGI:107810 |
600438 |
21780  |
Tfam | transcription factor A, mitochondrial |
absent optic nerve |
669 |
MGI:98724 |
190170 |
21802  |
Tgfa | transforming growth factor alpha |
microphthalmiaeyelids open at birthabnormal lens morphologycataractsincreased incidence of corneal inflammationcorneal scarringabnormal iris morphologyabnormal eyelid morphologyabnormal eye morphologyabnormal retinal vasculatureabnormal eyelid apertureabnormal eye muscle morphologyabsent Descemet membraneabnormal anterior eye segment morphologyabnormal eye anterior chamberabnormal meibomian gland morphology |
670 |
MGI:98725 |
190180 |
21803  |
Tgfb1 | transforming growth factor, beta 1 |
eye inflammationconjunctivitis |
671 |
MGI:98726 |
190220 |
21808  |
Tgfb2 | transforming growth factor, beta 2 |
persistence of hyaloid capillary systemfused cornea and lensretina hyperplasiadecreased corneal stroma thicknessabnormal posterior stroma morphologyabsent corneal endotheliumabsent Descemet membraneabnormal eye anterior chamberabnormal iris stroma morphologyabnormal eye posterior chamberabnormal corneal stroma morphologycorneal thinningabnormal retinal neuronal layer morphologyvitreous body deposition |
672 |
MGI:98743 |
190160 |
21834  |
Thrb | thyroid hormone receptor beta |
abnormal retinal photoreceptor morphologyabnormal retinal cone cell morphology |
673 |
MGI:98754 |
188826 |
21859  |
Timp3 | tissue inhibitor of metalloproteinase 3 |
abnormal retinal pigment epithelium morphologyabnormal Bruch membrane morphologyabnormal choroid vasculature |
674 |
MGI:105992 |
606781 |
21881  |
Tkt | transketolase |
microphthalmia |
675 |
MGI:1101059 |
602250 |
21942  |
Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 |
abnormal lacrimal gland morphologylacrimal gland inflammation |
676 |
MGI:2443306 |
|
216810  |
Tom1l2 | target of myb1-like 2 (chicken) |
abnormal eye distance/ positionabnormal cornea morphologyconjunctivitisexophthalmos |
677 |
MGI:108072 |
602355 |
22034  |
Traf6 | Tnf receptor-associated factor 6 |
abnormal meibomian gland morphology |
678 |
MGI:1914341 |
610396 |
67091  |
Trappc6a | trafficking protein particle complex 6A |
abnormal retinal pigmentation |
679 |
MGI:1933163 |
|
80890  |
Trim2 | tripartite motif-containing 2 |
decreased retinal ganglion cell numberretinal ganglion cell degenerationthin retinal inner nuclear layerthin retinal outer plexiform layer |
680 |
MGI:1330810 |
603273 |
22061  |
Trp63 | transformation related protein 63 |
absent eyelidsabsent lacrimal glandsabnormal corneal epithelium morphology |
681 |
MGI:1336991 |
601990 |
22062  |
Trp73 | transformation related protein 73 |
periorbital edemaconjunctivitis |
682 |
MGI:1354168 |
600415 |
50500  |
Ttpa | tocopherol (alpha) transfer protein |
retinal degenerationdisorganized retinal layersabnormal eye electrophysiology |
683 |
MGI:2651573 |
601197 |
22141  |
Tub | tubby candidate gene |
retinal degenerationdecreased retinal photoreceptor cell numberabnormal retinal vasculatureabnormal retinal photoreceptor layerabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal pigment epithelium morphologyabnormal eye electrophysiologyabnormal retinal neuronal layer morphologyabnormal retinal apoptosisretinal depositsretinal photoreceptor degenerationthin retinal outer nuclear layerretinal outer nuclear layer degenerationphotoreceptor outer segment degeneration |
684 |
MGI:109571 |
602280 |
22157  |
Tulp1 | tubby like protein 1 |
abnormal retina morphologyretinal degenerationdecreased retinal photoreceptor cell numberabnormal rod electrophysiologyabnormal cone electrophysiologyabnormal retinal neuronal layer morphologythin retinal outer nuclear layershort photoreceptor inner segmentabsent photoreceptor inner segmentabsent photoreceptor outer segmentshort photoreceptor outer segment |
685 |
MGI:2137520 |
605049 |
65960  |
Twsg1 | twisted gastrulation homolog 1 (Drosophila) |
abnormal lens inductionanophthalmiaabnormal retina morphology |
686 |
MGI:98880 |
606933 |
22173  |
Tyr | tyrosinase |
abnormal retinal photoreceptor morphologyabnormal retina morphologyretinal degenerationdecreased retinal photoreceptor cell numberabnormal visionreduced eye pigmentationabnormal aqueous drainage system morphologyabnormal retinal ganglion layer morphologyabnormal eye physiologyabnormal intraocular pressureabnormal eye electrophysiologyabsent eye pigmentation |
687 |
MGI:104294 |
600341 |
22174  |
Tyro3 | TYRO3 protein tyrosine kinase 3 |
abnormal retinal rod cell morphologyabnormal retinal cone cell morphology |
688 |
MGI:98881 |
115501 |
22178  |
Tyrp1 | tyrosinase-related protein 1 |
abnormal iris morphologyreduced eye pigmentationabnormal iris stroma morphologyiris atrophy |
689 |
MGI:1355274 |
603090 |
50933  |
Uchl3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
retinal degenerationabnormal retinal vasculatureabnormal retinal layer morphologyabnormal photoreceptor outer segment morphologyabnormal photoreceptor inner segment morphologyabnormal retinal outer nuclear layer morphologyabnormal retinal apoptosisthin retinal outer nuclear layerthin retinal outer plexiform layer |
690 |
MGI:1328357 |
604011 |
22248  |
Unc119 | unc-119 homolog (C. elegans) |
abnormal retina morphologyretinal degenerationabnormal retinal pigment epithelium morphologyabnormal eye electrophysiologythin retinal outer nuclear layer |
691 |
MGI:1919338 |
605242 |
72088  |
Ush1c | Usher syndrome 1C homolog (human) |
retinal degeneration |
692 |
MGI:1341292 |
608400 |
22283  |
Ush2a | Usher syndrome 2A (autosomal recessive, mild) homolog (human) |
abnormal retinal photoreceptor morphologyabnormal retinal photoreceptor layerabnormal eye electrophysiologyretinal cone cell degenerationretinal photoreceptor degenerationshort photoreceptor inner segmentshort photoreceptor outer segment |
693 |
MGI:1277163 |
604294 |
22326  |
Vax1 | ventral anterior homeobox containing gene 1 |
abnormal eye developmentabnormal optic nerve morphologyabnormal optic nerve innervationabnormal optic stalk morphologycoloboma |
694 |
MGI:1346018 |
604295 |
24113  |
Vax2 | ventral anterior homeobox containing gene 2 |
microphthalmiaabnormal optic nerve innervationcoloboma |
695 |
MGI:103178 |
192240 |
22339  |
Vegfa | vascular endothelial growth factor A |
persistence of hyaloid capillary systemabnormal retinal vasculatureretinal hemorrhage |
696 |
MGI:106199 |
601398 |
22340  |
Vegfb | vascular endothelial growth factor B |
corneal vascularization |
697 |
MGI:98935 |
192977 |
22359  |
Vldlr | very low density lipoprotein receptor |
abnormal retina morphologydecreased retinal photoreceptor cell numberabnormal ocular fundus morphologyabnormal retinal pigment epithelium morphologychoroidal neovascularizationabnormal retinal neuronal layer morphologyretinal photoreceptor degenerationdisorganized retinal inner nuclear layerthin retinal outer nuclear layerretinal outer nuclear layer degeneration |
698 |
MGI:1890816 |
605020 |
114889  |
Vsx1 | visual system homeobox 1 homolog (zebrafish) |
abnormal retina morphologyabnormal eye electrophysiology |
699 |
MGI:88401 |
142993 |
12677  |
Vsx2 | visual system homeobox 2 |
abnormal eye developmentmicrophthalmiasmall lensdisorganized retinal layersabsent optic nerveabnormal optic stalk morphologyabnormal optic cup morphologyreduced eye pigmentationeyelids fail to openabnormal lens developmentabnormal retinal progenitor morphology |
700 |
MGI:98962 |
601967 |
22422  |
Wnt7b | wingless-related MMTV integration site 7B |
persistence of hyaloid capillary system |
701 |
MGI:98967 |
|
103986  |
Wt | waltzer-type |
abnormal lens development |
702 |
MGI:99135 |
611153 |
22590  |
Xpa | xeroderma pigmentosum, complementation group A |
corneal opacity |
703 |
MGI:103557 |
278720 |
22591  |
Xpc | xeroderma pigmentosum, complementation group C |
photosensitivity |
704 |
MGI:104517 |
194364 |
22596  |
Xrcc5 | X-ray repair complementing defective repair in Chinese hamster cells 5 |
abnormal retina morphologyabnormal retinal apoptosis |
705 |
MGI:1344313 |
189909 |
21417  |
Zeb1 | zinc finger E-box binding homeobox 1 |
abnormal cornea morphologycorneal abrasionabnormal iridocorneal angleabnormal corneal stroma morphologyabnormal corneal endothelium morphologyabnormal corneal epithelium morphologycorneal adhesion to iris |
706 |
MGI:1344407 |
605802 |
24136  |
Zeb2 | zinc finger E-box binding homeobox 2 |
abnormal lens morphologysmall lensabnormal lens fiber morphology |
707 |
MGI:1890378 |
605467 |
65020  |
Zfp110 | zinc finger protein 110 |
abnormal retinal apoptosis |
708 |
MGI:99180 |
190700 |
22695  |
Zfp36 | zinc finger protein 36 |
conjunctivitis |
709 |
MGI:106676 |
300265 |
22773  |
Zic3 | zinc finger protein of the cerebellum 3 |
cataracts |
710 |
MGI:1929518 |
|
65100  |
Zic5 | zinc finger protein of the cerebellum 5 |
anophthalmiamicrophthalmiaabnormal optic vesicle formation |
711 |
MGI:87896 |
|
11452  |
act | adult cataract |
cataracts |
712 |
MGI:3510599 |
|
  |
awag | ages with abnormal gait |
cataractsabnormal cornea morphology |
713 |
MGI:2448976 |
|
  |
baln2 | balance 2 |
abnormal eye pigmentation |
714 |
MGI:2448982 |
|
  |
baln3 | balance 3 |
microphthalmia |
715 |
MGI:88159 |
|
12114  |
bh | brain hernia |
anophthalmiamicrophthalmia |
716 |
MGI:3580285 |
|
  |
biga1 | big a-wave 1 |
abnormal eye electrophysiology |
717 |
MGI:88207 |
|
12213  |
bs | blind-sterile |
microphthalmiacataracts |
718 |
MGI:88240 |
|
12285  |
cac | recessive cataract |
abnormal lens morphologycataractsabnormal lens fiber morphologyabnormal lens capsule morphology |
719 |
MGI:2653838 |
|
  |
chtl | chocolate-like |
abnormal eye pigmentation |
720 |
MGI:88415 |
|
12719  |
cl | clubfoot |
abnormal eye morphology |
721 |
MGI:2671571 |
|
  |
crf11 | craniofacial 11 |
microphthalmia |
722 |
MGI:2671584 |
|
  |
crf21 | craniofacial 21 |
microphthalmiaabnormal lens morphologycorneal opacity |
723 |
MGI:3033892 |
|
  |
crf27 | cranioacial 27 |
microphthalmia |
724 |
MGI:88500 |
|
12924  |
cri | cribriform degeneration |
abnormal retinal inner nuclear layer morphology |
725 |
MGI:2384508 |
|
  |
dblr | doubleridge |
anophthalmiamicrophthalmia |
726 |
MGI:2660661 |
|
  |
dcm | dense cataract and microphthalmia |
microphthalmiacataractsabnormal cornea morphologyabnormal pupil morphologyabnormal iris morphologyabnormal retina morphologyabnormal lens fiber morphologyabnormal optic stalk morphology |
727 |
MGI:94942 |
|
13545  |
dwg | dwarf grey |
cataracts |
728 |
MGI:1313145 |
|
14036  |
exma | exencephaly and severe microphthalmia/anophthalmia |
anophthalmiamicrophthalmia |
729 |
MGI:95471 |
|
14047  |
ey2 | eyeless 2 |
anophthalmiamicrophthalmiaabnormal eye morphology |
730 |
MGI:3038383 |
|
  |
eyes1 | eyes 1 |
microphthalmia |
731 |
MGI:3038384 |
|
  |
eyes2 | eyes 2 |
eyelids fail to open |
732 |
MGI:3577417 |
|
  |
eyes3 | eyes 3 |
microphthalmia |
733 |
MGI:95473 |
|
  |
f | flexed-tail |
eyelids fail to open |
734 |
MGI:3763279 |
|
  |
frg | froggy |
ocular hypertelorism |
735 |
MGI:3772850 |
|
  |
fsq | flying squirrel |
cataracts |
736 |
MGI:95696 |
|
14577  |
ge | greige |
abnormal eye pigmentation |
737 |
MGI:95793 |
|
14722  |
gp | gaping lids |
eyelids open at birthenlarged lenscorneal opacityabsent eyelidsblindness |
738 |
MGI:96287 |
|
15573  |
hug | hugger |
abnormal retina morphologyabnormal retinal inner nuclear layer morphologyabnormal retinal inner plexiform layer morphologyabnormal retinal neuronal layer morphologyretinal photoreceptor degenerationabnormal retinal rod cell outer segment morphologythin retinal inner nuclear layerthin retinal outer nuclear layer |
739 |
MGI:3707703 |
|
  |
irdc | ICR-derived retinal dysfunction cone |
abnormal rod electrophysiologyabnormal cone electrophysiology |
740 |
MGI:3707705 |
|
  |
irdr | ICR-derived retinal dysfunction rod |
abnormal cone electrophysiology |
741 |
MGI:1891208 |
|
  |
jrc | juvenile recessive cataract |
microphthalmiacataracts |
742 |
MGI:96806 |
|
16929  |
lop13 | lens opacity 13 |
cataracts |
743 |
MGI:96827 |
|
16964  |
lr | lens rupture |
abnormal lens morphologycataractsdislocated lens |
744 |
MGI:3794301 |
|
  |
ne | no eyelid |
microphthalmiaabnormal eyelid morphologycryptophthalmos |
745 |
MGI:2651818 |
|
  |
nmf12 | neuroscience mutagenesis facility, 12 |
abnormal retina morphology |
746 |
MGI:3053678 |
|
  |
nmf131 | neuroscience mutagenesis facility, 131 |
persistence of hyaloid capillary systemmicrophthalmiacataractscorneal scarringretinal degenerationabnormal vitreous body |
747 |
MGI:3041627 |
|
  |
nmf166 | neuroscience mutagenesis facility, 166 |
cataractsabnormal eye anterior chamber |
748 |
MGI:3032505 |
|
  |
nmf192 | neuroscience mutagenesis facility, 192 |
abnormal retinal pigmentation |
749 |
MGI:3574830 |
|
  |
nmf195 | neuroscience mutagenesis facility 195 |
abnormal retina morphology |
750 |
MGI:3056296 |
|
  |
nmf240 | neuroscience mutagenesis facility, 240 |
retinal degeneration |
751 |
MGI:3611320 |
|
  |
nmf246 | neuroscience mutagenesis facility, 246 |
retinal degeneration |
752 |
MGI:3511346 |
|
  |
nmf247 | neuroscience mutagenesis facility, 247 |
abnormal retina morphologyvitreal fibroplasia |
753 |
MGI:3611684 |
|
  |
nmf268 | neuroscience mutagenesis facility, 268 |
abnormal retina morphology |
754 |
MGI:3611305 |
|
  |
nmf282 | neuroscience mutagenesis facility, 282 |
retinal degeneration |
755 |
MGI:2651830 |
|
  |
nmf67 | neuroscience mutagenesis facility, 67 |
abnormal retina morphologydisorganized retinal layers |
756 |
MGI:2671651 |
|
  |
nse1 | neurological/sensory 1 |
abnormal eyelid morphology |
757 |
MGI:2671652 |
|
  |
nse2 | neurological/sensory 2 |
microphthalmia |
758 |
MGI:97425 |
|
18287  |
oe | open eyelids |
abnormal eye developmentmicrophthalmiaeyelids open at birthabnormal cornea morphologycorneal opacityabnormal retina morphologyabnormal eyelid morphologyabnormal eye morphologyearly eyelid openingabnormal timing of postnatal eyelid openingabnormal lens development |
759 |
MGI:3576022 |
|
  |
opey | open eyes |
eyelids open at birth |
760 |
MGI:1928991 |
|
  |
pcat | perinatal cataract 6 |
cataracts |
761 |
MGI:1890502 |
|
117201  |
rct | Rinshoken cataract |
microphthalmiaabnormal lens morphologycataracts |
762 |
MGI:2668209 |
|
  |
rd13 | retinal degeneration 13 |
abnormal retina morphology |
763 |
MGI:3689098 |
|
  |
rdp | reduced pigment |
reduced eye pigmentation |
764 |
MGI:3718121 |
|
  |
ru2l | ruby-eye 2-like |
reduced eye pigmentation |
765 |
MGI:3717409 |
|
  |
sabe | small and bugged-eyed |
exophthalmosenlarged optic nerve |
766 |
MGI:3580364 |
|
  |
serg1 | small ERG 1 |
abnormal eye electrophysiology |
767 |
MGI:3580372 |
|
  |
serg2 | small ERG 2 |
abnormal eye physiology |
768 |
MGI:3580378 |
|
  |
serg3 | small ERG 3 |
abnormal eye electrophysiology |
769 |
MGI:3580385 |
|
  |
serg4 | small ERG 4 |
abnormal eye electrophysiology |
770 |
MGI:1345178 |
|
24054  |
sgl | scraggly |
conjunctivitis |
771 |
MGI:99514 |
|
20427  |
shmy | shimmy |
delayed eyelid opening |
772 |
MGI:2671615 |
|
  |
skc22 | skin/coat color 22 |
abnormal eye pigmentation |
773 |
MGI:2671616 |
|
  |
skc23 | skin/coat color 23 |
abnormal eye pigmentation |
774 |
MGI:2671601 |
|
  |
skc3 | skin/coat color 3 |
eyelids fail to open |
775 |
MGI:3612271 |
|
  |
sky | severe kyphosis |
eyelids open at birth |
776 |
MGI:98757 |
|
21864  |
tip | tippy |
optic nerve degeneration |
777 |
MGI:2684125 |
|
  |
tirs | tiresias |
anophthalmiamicrophthalmia |
778 |
MGI:2670266 |
|
  |
tmgc22 | Tennessee Mouse Genome Consortium 22 |
abnormal ocular fundus morphologyabnormal choroid morphologyabnormal choroid pigmentationabnormal retinal pigment epithelium morphologyabnormal Bruch membrane morphology |
779 |
MGI:2670269 |
|
  |
tmgc23 | Tennessee Mouse Genome Consortium 23 |
abnormal retinal vasculatureabnormal posterior uvea morphologyabnormal retinal pigment epithelium morphology |
780 |
MGI:2670274 |
|
  |
tmgc24 | Tennessee Mouse Genome Consortium 24 |
abnormal optic nerve morphologyabnormal posterior uvea morphologyabnormal optic disc morphology |
781 |
MGI:2670425 |
|
  |
tmgc25 | Tennessee Mouse Genome Consortium 25 |
abnormal ocular fundus morphologyabnormal choroid morphologyabnormal choroid pigmentationabnormal retinal pigment epithelium morphologyabnormal Bruch membrane morphology |
782 |
MGI:2670265 |
|
  |
tmgc29 | Tennessee Mouse Genome Consortium 29 |
abnormal ocular fundus morphologyabnormal choroid morphologyabnormal choroid pigmentationabnormal retinal pigment epithelium morphologyabnormal Bruch membrane morphology |
783 |
MGI:3053521 |
|
  |
tmgc36 | Tennessee Mouse Genome Consortium 36 |
microphthalmia |
784 |
MGI:3606748 |
|
  |
uwl | underwhite-like |
reduced eye pigmentation |
785 |
MGI:3612834 |
|
  |
whe | white eyes |
increased incidence of corneal inflammationcorneal opacityearly eyelid openingcorneal vascularizationcorneal adhesion to iris |