Projects and Investigators

FY 2001 Projects

University of Colorado School of Medicine

Objective

Development of a next generation human papillomavirus vaccine.

Program Description

Investigators will conduct preclinical development of a next generation human papillomavirus vaccine. Human papillomaviruses play a critical role in the development of several cancers, the most common being cervical cancer. A second generation papillomavirus vaccine that is both economical and stable is being developed. Preliminary data showed it offers protection against experimental viral challenge in the canine model. RAPID support will include:

• In vivo and in vitro preclinical efficacy testing,
• Preclinical toxicology,
• GMP production, formulation, and an IND support.

Contact Information

Robert L. Garcea
University of Colorado School of Medicine
Boulder, CO
Tel: 303-3154-3247
Fax: 303-315-3244
E-mail: Bob.Garcea@UCHSC.edu