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Isochromosomes

Definition(s)

A metacentric chromosome produced during mitosis or meiosis when the centromere splits transversely instead of longitudinally; the arms of such chromosome are equal in length and genetically identical, however, the loci are positioned in reverse sequence in the two arms.

Definition from: Office of Rare DiseasesThis link leads to a site outside Genetics Home Reference. at the National Institutes of Health

A chromosome produced by transverse splitting of the centromere so that both arms are from the same side of the centromere, are of equal length, and possess identical genes.

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

Related discussion in the Handbook

 
Published: January 23, 2009