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Recent Publications
2000
- Staudt LM. The molecular and cellular origins of Hodgkin's disease. J Exp Med, 2000; 191:207-212
- Alizadeh A, Eisen M, Davis RE, Ma CA, Lossos I, Rosenwald A, Boldrick J, Sabet H, Tran T, Yu X, Powell J, Yang L, Marti G, Moore T, Hudson J, Chan WC, Greiner TC, Weissenberger DD, Armitage JO, Levy R, Grever MR, Byrd JC, Botstein D, Brown PO, Staudt LM. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403:503-511.
- Alizadeh AA, Staudt LM. Genomic-scale gene expression profiling of normal and malignant immune cells. Curr Opin Immunol 2000, 12:219-225.
- Staudt LM. The expression of the genome during immune responses. Curr Opin Immunol 2000, 12:199-200.
- Staudt LM, Brown PO. Genomic views of the immune system. Annual Reviews of Immunology, 2000, 18:829-859.
- Hastie T, Tibshirani R, Eisen MB, Alizadeh A, Levy R, Staudt L, Chan WC, Botstein D, Brown P. 'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns. Genome Biology 2000, 1:3.1-3.21.
- Lossos IS, Alizdeh AA, Eisen MB, Chan WC, Brown PO, Botstein D, Staudt LM, Levy R. Ongoing immunoglobulin heavy chain somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. PNAS 2000, in press.
- Ma C, Staudt LM. Molecular definition of the germinal center stage of B cell differentiation. Royal Society London Philosophical Transactions B 2000, in press.
- Staudt LM. Gene expression physiology and pathophysiology of the immune system. Immunology Today 2000, in press.
- Shaffer AL, Yu X, He Y, Boldrick J, Chan E, Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation and cell cycle control. Immunity 2000, 13:1-20
1996-1999
- Allman D, Jain A, Dent A, Maile R, Selvaggi T, Kehry MR, Staudt LM. BCL-6 expression during B cell activation. Blood 1996;87:5257-5268.
- Seyfert V, Allman D, He Y, Staudt LM. Transcriptional repression by the proto-oncogene BCL-6. Oncogene 1996;12:2331-2342.
- Dent AL, Shaffer A, Yu X, Allman D, Staudt LM. Control of inflammation, cytokine expression and germinal center formation by BCL-6. Science 1997;276:589-592.
- Dent AL, Hu-Li J, Paul WE, Staudt LM. TH2-type Inflammation in the Absence of IL-4 and STAT6. Proc Natl Acad Sci, 1998; 95:13823-13828.
- Alizadeh A, Eisen M, Brown PO, Staudt LM. Probing Lymphocyte Biology by Genomic-scale Gene Expression Analysis. J Clin Immunol, 1998;18:373-379.
- Iyer, VR, Eisen, MD, Ross, DT, Schuler, G, Moore, T, Lee, J, Trent, JM, Staudt, LM, Hudson, J, Boguski, M, Lashkari, D, Shalon, D, Botstein, D, Brown, PO The transcriptional response of human fibroblasts to serum. Science 1999;283:83-87.
- Dent AL, Shaffer A, Yu X, Staudt LM. Regulation of Lymphocyte Cell Fate Decisions and Lymphomagenesis by BCL-6, Int Rev Immunol 1999;18:381-403.
- Dent AL, Doherty, TM, Paul WE, Sher, A, Staudt LM. BCL-6-deficient mice reveal an IL-4-independent STAT6-dependent pathway that controls susceptibility to infection by Leishmania major. J Immunol 1999; 163:2098-2103.
- Alizadeh A, Eisen M, Davis RE, Ma CA, Sabet H, Tran T, Powell JI, Yang L, Marti GE, Moore DT, Hudson JR, Chan WC, Greiner T, Weisenberger D, Armitage JO, Lossos I, Levy R, Botstein D, Brown PO, Staudt LM. The Lymphochip: A specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harbor Symposium on Quantitative Biology, 1999; 64:71-78
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