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Chemopreventive Agent Development Research Group

About the Research Program

Mission

  • Provides scientific and administrative oversight for preclinical chemoprevention agent development up to early phase I chemopreventive agent research utilizing physiological endpoints in healthy volunteers.
  • Research includes all classes of agents (e.g. pharmaceuticals, micronutrients) and includes synthesis/extraction, and mechanistic studies (e.g. assays using high-throughput gene analysis technology, cell cultures from high-risk tissue, carcinogenesis related biochemical activities, technologies focusing on molecular targets and their modulation leading to the identification and optimization of promising chemopreventive agents).
  • Assists extramural investigators to bridge the gap between discovery and clinical testing through management of a program of Rapid Access to Preventive Intervention Development.
  • Works with DCP clinical research groups in clinical trials development, agent acquisition, IND - directed toxicology and related research.
  • Communicates with extramural and intramural investigators and industry and provides technical support and research resources for chemopreventive agent development.

Staff


Name/EmailRoom/Phone
Martha Basinger
basingem@mail.nih.gov		 EPN 2106
(301) 594-0422
Dan Boring, RPh, PhD
boringd@mail.nih.gov		 EPN 2109
(301) 594-1165
Izzy Kapetanovic, PhD
kapetani@mail.nih.gov		 EPN 2116
(301) 435-5011
Levy Kopelovich, PhD
kopelovl@mail.nih.gov		 EPN 2114
(301) 594-0467
Ronald Lubet, PhD
lubetr@mail.nih.gov		 EPN 2110
(301) 594-0457
Loretta Mobley
mobleyl@mail.nih.gov		 EPN 2117
(301) 402-3668
Winfred Malone, PhD, MPH
malonew@mail.nih.gov		 EPN 2122
(301) 594-0460
Marjorie Perloff, MD
perloffm@mail.nih.gov		 EPN 2112
(301) 594-0466
Vernon Steele, PhD, MPH- Acting Director
steelev@mail.nih.gov		 EPN 2108
(301) 594-0420

Phone Number: (301) 496-8563
Fax Number: (301) 402-0553 or (301) 594-2943

U.S. Mail Address:

Chemopreventive Agent Development
Research Group, DCP, NCI
Executive Plaza North, Room 2117
6130 Executive Blvd
Bethesda, MD 20892-7322

Commercial Delivery Address:

Chemopreventive Agent Development
Research Group, DCP, NCI
Executive Plaza North, Room 2117
6130 Executive Blvd
Rockville, MD 20852

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