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Manufacturer
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| Prestone Products Corp. |
| Div., Honeywell International, Inc. |
| 39 Old Ridgebury Road |
| Danbury |
| CT |
| 06811 |
| 203-830-7800 |
| 203-830-7904 |
| 800-890-2075 |
| 2008-01-09 |
| Products by this manufacturer |
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| The following information (Health Effects, Handling/Disposal, and Ingredients) is taken from the product label and/or the Material Safety Data Sheet (MSDS) prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS.
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Health Effects
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| Harmful or fatal if swallowed or inhaled. Do not drink antifreeze or solution. Ethylene glycol base. Avoid inhaling mist or hot vapors. If inhaled, remove to fresh air. Ethylene glycol causes birth defects in laboratory animals. Do not store in open or unlabeled containers. Wash thoroughly after handling. Solution is poisonous to animals. Keep out of reach of children. Antifreeze/coolant is poisonous. Clean up any leaks or spills immediately. Tighten the child resistant cap and store antifreeze away from children and animals. |
From MSDS
EMERGENCY OVERVIEW
Clear, green liquid with a mild, sweet odor. Eye and upper respiratory irritant. May cause nausea, vomiting, headache, drowsiness, blurred vision, convulsions, coma or death if ingested or inhaled. Prolonged or repeated skin contact may cause dermatitis or skin sensitization.
POTENTIAL HEALTH EFFECTS:
INHALATION: May cause irritation of the nose and throat with headache,
particularly from mists. High vapor concentrations caused, for example, by heating the material in an enclosed and poorly ventilated workplace, may produce nausea, vomiting, headache, dizziness and irregular eye movements.
SKIN CONTACT: No evidence of adverse effects from available information.
EYE CONTACT: Liquid, vapors or mist may cause discomfort in the eye with persistent conjunctivitis, seen as slight excess redness or conjunctiva. Serious corneal injury is not anticipated.
INGESTION: May cause abdominal discomfort or pain, nausea, vomiting, dizziness, drowsiness, malaise, blurring of vision, irritability, back pain, decrease in urine output, kidney failure, and central nervous system effects, including irregular eye movements, convulsions and coma. Cardiac failure and pulmonary edema may develop. Severe kidney damage which may be fatal may follow the swallowing of ethylene glycol. A few reports have been published describing the development of weakness of the facial muscles, diminishing hearing, and difficulty with swallowing, during the late stages of severe poisoning.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: The available toxicological
information and a knowledge of the physical and chemical properties of the material suggest that overexposure in unlikely to aggravate existing medical conditions.
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From MSDS
Prolonged or repeated inhalation exposure may produce signs of central nervous system involvement, particularly dizziness and jerking eye movements. Prolonged or repeated skin contact may cause skin sensitization and an associated dermatitis in some individuals. Ethylene glycol has been found to cause birth defects in laboratory animals. The significance of this finding to humans has not been determined.
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From MSDS
None of the components of these products is listed as a
carcinogen or suspected carcinogen by IARC, NTP or OSHA.
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From MSDS
INHALATION: Remove the victim to fresh air. If breathing has stopped
administer artificial respiration. If breathing is difficult, have medical personnel administer oxygen. Get medical attention.
SKIN CONTACT: Remove contaminated clothing. Immediately wash contacted
area thoroughly with soap and water. If irritation persists, get medical
attention.
EYE CONTACT: Immediately flush eyes with large amounts of water for 15
minutes. Get medical attention if irritation persists.
INGESTION: Seek immediate medical attention. Immediately call local poison control center or go to an emergency department. Never give anything by mouth to or induce vomiting in an unconscious or drowsy
person.
NOTES TO PHYSICIAN: The principal toxic effects of ethylene glycol, when swallowed, are kidney damage and metabolic acidosis. Ethanol is antidotal and its early administration may block the formation of nephrotoxic metabolites of ethylene glycol in the liver. The objective is to rapidly achieve and maintain a blood ethanol level of approximately 100 mg/dl by giving a loading dose of ethanol followed by a maintenance dose. Intravenous administration of ethanol is the preferred route. Hemodialysis may be required. 4-Methylpyrazole, a
potent inhibitor of alcohol dehydrogenase, has been used therapeutically to decrease the metabolic consequences of ethylene glycol poisoning. Additional therapeutic modalities which may decrease the adverse consequences of ethylene glycol metabolism are the administration of both thiamine and pyridoxine. Pulmonary edema with hypoxemia has been described in a number of patients following poisoning with ethylene glycol. Respiratory support
with mechanical ventilation may be required. There may be cranial nerve involvement in the late stages of toxicity from swallowed ethylene glycol. In particular, effects have been reported involving the seventh, eighth, and ninth cranial nerves, presenting with bilateral facial paralysis, diminished hearing and
dysphagia.
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| 1 |
| 2 |
| 0 |
0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe;
N = No information provided by manufacturer; * = Chronic Health Hazard |
| 1998-07-24 |
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Handling/Disposal
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From MSDS
DANGER: Harmful or Fatal if Swallowed. Do not drink antifreeze or solution. Avoid eye and prolonged or repeated skin contact. Avoid breathing vapors or mists. Wash exposed skin thoroughly with soap and water after use. Do not store in opened or unlabeled containers. Keep container away from open flames and excessive heat. Do not reuse empty containers unless properly cleaned. Empty containers retain product residue and may be dangerous. Do not cut, weld, drill, etc. containers, even empty. Sudden release of hot organic chemical vapors or mists from process equipment operating at elevated temperature and pressure, or sudden ingress of air into vacuum equipment, may result in ignitions without any obvious ignition sources. Published "autoignition" or "ignition" temperatures cannot be treated as safe operating temperatures in chemical processes without analysis of the actual process conditions. Use of this product in elevated temperature applications should be
thoroughly evaluated to assure safe operating conditions.
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From MSDS
Dispose of product in accordance with all local, state/provincial and federal regulations.
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Ingredients from MSDS/Label
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