I REMBRANDT (Repository of Molecular Brain Neoplasia Data)

REMBRANDT is a robust bioinformatics initiative that leverages data warehousing technology to host and integrate clinical and functional genomics data from clinical trials involving patients suffering from Gliomas. REMBRANDT also supports the Glioma Molecular Diagnostic Initiative’s (GMDI) effort led by the National Cancer Institute’s (NCI) Center for Cancer Research (CCR) Neuro-Oncology Branch. In addition, the NCI Center for Bioinformatics (NCICB) has been developing tools and infrastructure components that facilitate the capture and integration of data associated with REMBRANDT in support of translational research. The National Institute of Neurological Disorders and Stroke (NINDS) is a leader in the neuroscience community in shaping the future of brain cancer research and is contributing resources and capabilities to this effort. Together, the CCR, NCICB, and NINDS can exploit  existing technologies and develop new integrative components supporting ongoing and future cancer research initiatives towards understanding the “molecular signatures” of different brain tumor sub-types.  REMBRANDT will provide researchers the ability to perform ad hoc querying and reporting across multiple data domains, such as gene expression, chromosomal aberrations and clinical data.

To learn more about REMBRANDT, visit http://caintegrator-info.nci.nih.gov/rembrandt.

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