The
NIH DIrector's Pioneer Award Program
To stimulate high-risk, high-impact medical research, the National Institutes
of Health (NIH) is inviting nominations for the NIH Director's Pioneer
Award Program, part of a series of far-reaching initiatives known collectively
as the NIH Roadmap for Medical Research.
Six new data sets have been added to the current Limited Access Data Web site:
Coronary
Artery Surgery Study (CASS)
This project
included two components, a registry of patients undergoing angiography at
participating sites and a randomized trial component. The primary objective of
the registry was to provide information regarding the effects of coronary artery
surgery on patients with ischemic heart disease within the clinical course of
treatment.
Cardiac
Arrhythmia Suppression Trial (CAST)
This
trial sought to evaluate the efficacy and safety of arrhythmia suppression
therapy in patients with asymptomatic or mildly symptomatic ventricular
arrhythmia after myocardial infarction.
High
Frequency Ventilation in Premature Infants (HIFI)
This project evaluates the hypothesis that high frequency
oscillatory ventilation in preterm infants would reduce the incidence of
mortality and pulmonary complications compared to conventional mechanical
ventilation.
Multiple
Risk Factor Intervention Trial (MRFIT)
This trial sought to evaluate the effect of multiple risk factor
intervention on mortality from coronary heart disease in high risk men.
Acute
Respiratory Distress Syndrome Clinical Network (ARDSNet)
The ARDS Network is a consortium of clinical centers and a
coordinating center to design and test novel therapies for the treatment of
Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS).
Dietary
Approaches to Stop Hypertension - Sodium (DASH-Sodium) Trial
The primary
objective of the DASH-Sodium Trial was to test the effects of two dietary
patterns and three sodium intake levels on blood pressure in adult men and women
with blood pressure higher than optimal or at stage 1 hypertension (systolic
120-159 mm Hg and diastolic 80-95 mm Hg).