I TCGA Related Links

Several initiatives will support and complement The Cancer Genome Atlas Pilot Project. Read more about these programs listed below.

caArray Data Portal
The National Cancer Institute's (NCI) caArray Data Portal is an open source microarray data management system that allows users to submit, annotate, analyze, and download microarray data through visualization tools to allow users to understand the connections and correlations between genes and proteins. Registration is required to submit data or access protected data. To learn more about caArray, click here.

Cancer Genetic Markers of Susceptibility Data Portal
The National Cancer Institute's (NCI) Cancer Genetic Markers of Susceptibility (CGEMS) Data Portal allows users to search data to conduct genome-wide association studies (GWAS) with follow-up replication studies to identify common, inherited gene variations that either increase or decrease the risk for cancer. The two cancers currently being studied by the CGEMS project are prostate cancer and breast cancer. To learn more about the Cancer Genetic Markers of Susceptibility Data Portal, click here.

Cancer Genome Anatomy Project
The National Cancer Institute's (NCI) Cancer Genome Anatomy Project (CGAP) seeks to determine the gene expression profiles of normal, precancer, and cancer cells in an effort to improve detection, diagnosis, and treatment for patients. CGAP collaborates with scientists worldwide to increase its scientific expertise and expand its database for the benefit of all cancer researchers. To learn more about the Cancer Genome Anatomy Project, click here.

COSMIC Mutation Database
COSMIC is a database that stores and displays somatic mutation information and related details and contains information related to human cancers. The mutation data and associated information is extracted from the primary literature and entered into the COSMIC database, and can be queried by tissue, histology, or gene. COSMIC is part of The Sanger Institute, a genome research institute primarily funded by the Wellcome Trust. To learn more about COSMIC, click here.

REMBRANDT
The National Cancer Institute's (NCI) REpository for Molecular BRAin Neoplasia DaTa (REMBRANDT) initiative is a robust bioinformatics knowledgebase framework that leverages data warehousing technology to host and integrate clinical and functional genomics data from clinical trials involving patients suffering from Gliomas. To learn more about REMBRANDT, click here.

Tumor Sequencing Project Consortium
The National Human Genome Research Institute's (NHGRI) Tumor Sequencing Project (TSP) Consortium is a collaboration effort that pilots approaches to large-scale identification of genomic changes in tumors and aims to sequence the exonic regions of 1,000 genes in almost 200 specimens of adenocarcinoma of the lung. The TSP Consortium also uses high density SNP genotyping arrays for high resolution identification of changes in chromosomal copy number. To learn more about the Tumor Sequencing Project Consortium, click here. To access data from the Tumor Sequencing Project, click here.