bold indicates screening center PI

2006

1. Alfonso, C., McHeyzer-William, M.G., & Rosen, H. (2006). CD69 down-modulation and inhibition of thymic egress by short and long-term selective chemical agonism of S1P1 receptors. Eur J Immunol 36, 149-59.

2. Auld, D.S, Johnson, R.L., Zhang, Y., Veith, H., Jadhav, A., Yasgar, A., Simeonov, A., Zheng, W., Martinez, E.D., Westwick, J.K., Austin, C.P., & Inglese, J. (2006). Fluorescent Protein-Based Cellular Assays Analyzed by Laser-Scanning Microplate Cytometry in 1536-Well Plate Format. Methods in Enzymology, 414: 566-589.

3. Bologa, C.G., Revankar, C.M., Young, S.M., Edwards, B.S., Arterburn, J.B., Kiselyov, A.S., Parker, M.A., Tkachenko, S.E., Savchuck, N.P., Sklar, L.A., Oprea, T.I., & Prossnitz, E.R. (2006). Virtual and biomolecular screening converge on a selective agonist for GPR30, Nat Chem Biol, 2, 207-212.

4. Chun, J., & Rosen, H. (2006). Lysophospholipid receptors as potential drug targets in tissue transplantation and autoimmune diseases. Curr. Pharm. Des. 12, 161-71.

5. Edwards, B. S., Young, S. M., Oprea, T.I., Bologa, C. G., Prossnitz, E. R., & Sklar, L.A. (2006). Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform. Nat Protoc, 1, 59-66.

6. Fara, D. C., Oprea, T.I., Prossnitz, E.R., Bologa, C.G., Edwards, B.S., & Sklar, L.A. (2006). Integration of virtual and physical screening. Drug Discovery Today, 3, 377-385.

7. Hensler, M.E., Bernstein, G., Nizet, V., & Nefzi, A. (2006). Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library. Bioorg Med Chem Lett 16: 5073-50739.

8. Inglese, J, Auld, D.S., Jadhav, A., Johnson, R.L., Simeonov, A., Yasgar, A., Zheng, W., & Austin, C.P. (2006). Quantitative high-throughput screening- A titration-based approach that efficiently identifies biological activities in large chemical libraries. Proceedings of the National Academy of Sciences of the United States of America, 103: 11473-11478.

9. Lazo, J.S. (2006). Roadmap or Roadkill: A Pharmacologist’s Analysis of the NIH Molecular Libraries Initiative. Molecular Interventions, 6: 240.

10. Mayer, T., Jagla, B., Wyler, M.R., Kelly, P.D., Aulner, N., Beard, M., Barger, G., Tobben, U., Smith, D.H., Branden, L., & Rothman, J.E. (2006). Cell-Based Assays Using Primary Endothelial Cells to Study Multiple Steps in Inflammation. Methods in Enzymology, 414, 266-283.

11. Nefzi, A., Ostresh, J.M., Appel, J.R., Bidlack, J., Dooley, C.T., & Houghten, R.A. (2006). Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries. Bioorg Med Chem Lett, 16, 4332-4338.

12. Oprea, T. I., & Tropsha A. (2006). Target, chemical and bioactivity databases- integration is key. Drug Discovery Today, 3, 357-365.

13. Parker, C.N, Shamu, C.E., Kraybill, B., Austin, C.P., & Bajorath, J. (2006). Measure, mine, model, and manipulate: the future for HTS and chemoinformatics? Drug Discovery Today, 11: 863.

14. Prossnitz, E., Arterburn, J., Edwards, B., Sklar, L., & Oprea, T. (2006). Steroid-Binding GPCRs: New Drug Discovery Targets for Old Ligands? Expert Opinion in Drug Discovery, 1, 137-150.

15. Ramesh, C., Bryant, B., Nayak, T., Revenkar, C.M., Anderson, T., Carlson, K.E., Katzenellenbogen, J.A., Sklar, L.A., Norenberg, J.P., Prossnitz, E.R., & Arterburn, J.B. (2006). Linkage Effects on Binding Affinity and Activation of GPR30 and Estrogen Receptors ER α/β with Tridentate Pyridin-2-yl Hydrazine Tricarbonyl-Re/99mTc(I) Chelates. Journal of the American Chemical Society, 128, 14476-14477.

16. Sanna, M. G., Wang, S., Gonzalez-Cabrera, P.J., Don, A., Marolais, D., Mattheu, M. P., Wei, S.H., Parker, I., Jo, E., Cheng, W., Calahan, M.D., Wong, C., & Rosen, H. (2006). Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nature Chemical Biology, 2, 434-441.

17. Sklar, L.A. (2006). NM Molecular Libraries Screening Center: Enhancing Drug Discovery with Cheminformatics. Society for Biomolecular Screening News, 22, 1.

18. Tessema, M., Simons, P.C., Cimino, D.F., Sanchez, L., Waller, A., Posner, R.G., Wandinger-Ness, A., Prossnitz, E.R., & Sklar, L.A. (2006). Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH, Cytometry A, 69, 326-334.

Edited by CR: 06/16/08