Mutation Mass Shifts
Delta masses between various amino acids
An aid for explaining how an observed mass change could represent an AA mutation.


This table lists the delta masses between various amino acids and can be used to help explain how an observed mass change could represent an AA mutation.

  • Residues DOWN the left indicate the EXPECTED residues.
  • Residues ACROSS the top indicate the MUTANT residues.
    GASPVTCL/INDQ/KEMHFRYW
    5771879799101103113114115128129131137147156163186
    ________________________________________________________________________
    G 57 143040424446565758717274809099106129
    A 71 -14162628303242434457586066768592115
    S 87 -30-16101214162627284142445060697699
    P 97 -40-26-102461617183132344050596689
    V 99 -42-28-12-2241415162930323848576487
    T 101 -44-30-14-4-221213142728303646556285
    C 103 -46-32-16-6-4-21011122526283444536083
    L/I113 -56-42-26-16-14-12-10121516182434435073
    N 114 -57-43-27-17-15-13-11-111415172333424972
    D 115 -58-44-28-18-16-14-12-2-11314162232414871
    Q/K128 -71-57-41-31-29-27-25-15-14-1313919283558
    E 129 -72-58-42-32-30-28-26-16-15-14-12818273457
    M 131 -74-60-44-34-32-30-28-18-17-16-3-2616253255
    H 137 -80-66-50-40-38-36-34-24-23-22-9-8-610192649
    F 147 -90-76-60-50-48-46-44-34-33-32-19-18-16-1091639
    R 156 -99-85-69-59-57-55-53-43-42-41-28-27-25-19-9730
    Y 163 -106-92-76-66-64-62-60-50-49-48-35-34-32-26-16-723
    W 186 -129-115-99-89-87-85-83-73-72-71-58-57-55-49-39-30-23
    All values are (column-row). The mass difference observed is consistent with a ROW to COLUMN mutation.