I News and Announcements
News Releases and Announcements
January 8, 2009 |
New*
NCI Announces New Funding to Support TCGA Genome Characterization Centers and Genome Data Analysis Centers |
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September 4, 2008 |
The Cancer Genome Atlas Reports First Results of Comprehensive Study of Brain Tumors: Large-Scale Effort Identifies New Genetic Mutations, Core Pathways |
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July 2, 2007 |
The Cancer Genome Atlas Awards Funds for Technology Development |
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November 20, 2006 |
NHGRI Funds Large-Scale Sequencing Centers |
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October 16, 2006 |
NIH Announces Two Integral Components of The Cancer Genome Atlas Pilot Project |
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September 13, 2006 |
National Institutes of Health to Map Genomic Changes of Lung, Brain, and Ovarian Cancers |
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December 13, 2005 |
NIH Launches Comprehensive Effort to Explore Cancer Genomics |
In the News
Featured Articles
Genome Surveys Reveal Complexity of Brain Cancers
September 9, 2008
NCI Cancer Bulletin
Volume 5 / Number 18
This NCI Cancer Bulletin article features one of the most comprehensive studies to date of the molecular changes underlying brain cancer. The TCGA Research Network analyzed 206 glioblastoma (GBM) brain tumors using an integrated approach based on multiple types of genetic data and clinical information. Highlighting three genes found in the disease – ERBB2, NF1, and TP53, these findings significantly expand our current knowledge about the genetic networks involved in this deadly disease and potential therapeutic strategies.
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
September 4, 2008
Nature
The Cancer Genome Atlas Research Network reported the first results of its large-scale, comprehensive study of the most common form of brain cancer, glioblastoma (GBM) in the Sept. 4, 2008 advance online edition of the journal Nature. Among the TCGA findings are the identification of many gene mutations involved in GBM, including three previously unrecognized mutations that occur with significant frequency; and the delineation of core pathways disrupted in this type of brain cancer. One of the most exciting results is an unexpected observation that points to a potential mechanism of resistance to a common chemotherapy drug used for brain cancer.
TCGA Moving Molecular Oncology Forward
May 2008
NCI Cancer Bulletin
Dr. Daniela S. Gerhard, director of the Office of Cancer Genomics, reviews the progress of The Cancer Genome Atlas (TCGA) pilot project with molecular oncology advances seen through international data sharing among researchers in addition to tools and technologies being developed to enable researchers to delve further into the molecular machinery of cancer.
Mapping the Cancer Genome
Scientific American
March 2007
Francis S. Collins, director of the National Human Genome Research Institute, and Anna D. Barker, deputy director for Advanced Technologies and Strategic Partnerships at the National Cancer Institute, discuss the importance of creating a comprehensive catalogue of the genomic changes involved in cancer through The Cancer Genome Atlas (TCGA).
News Conference
The Cancer Genome Atlas Launch
December 13, 2005
National Press Club
Washington, D.C.
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