Access MLPCN Resources
The MLPCN resource can be accessed by any member of the scientific community through an NIH grant based application process. There are three possible ways,
If you have an existing HTS-ready assay (in 96, 384, 1536-well plate or flow cytometry), then you can:
- Ask for Technical Assistance here
- Apply through R03 Assay Implementation for peer review organized by CSR, or
If you have a potentially HTS-compatible assay (in test tube or 96-well plate)
- Ask for Technical Assistance here
- Apply through R21 Assay Development for peer review organized by CSR, or
If you are a PI of an existing HTS assay grants or contracts (R21, R01 etc) you can
- Ask for Technical Assistance here.
- Apply for fast track entry to MLPCN.
Benefits of using the MLPCN for an assay provider?
There are a number of benefits to using the MLPCN for your small molecule bioassays. Some of these are highlighted below:
- In collaboration with an MLPCN center you can get a small molecule probe with characteristics specified in the grant proposal. This includes the primary HTS screen and follow-up cheminformatics/informatics and medicinal chemistry.
- This is possible with completely free or minimal costs to the assay provider.
- Get free access to one of the largest academic screening collection around. The small molecule collection includes the (possibly) largest publicly available collection of known bioactives, a range of novel chemical classes sourced from the academic community, and a diverse set of commercially available compounds.
- The network of MLPCN centers have a broad range of expertise in different assay types and formats and scientific expertise in a range of disease biology.
