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(51) Indirect for 2004 Publications


<Cites Austin,C., et al. 2004>

1. Judson, R., Richard, A., Dix, D., Houck, K., Elloumi, F., Martin, M., et al. (2008). ACToR - aggregated computational toxicology resource. Toxicology and Applied Pharmacology, 233(1), 7-13.

2. Lehár, J., Stockwell, B. R., Giaever, G., & Nislow, C. (2008). Combination chemical genetics. Nature Chemical Biology, 4(11), 674-681.

3. Weis, D. C., Visco Jr., D. P., & Faulon, J. -. (2008). Data mining PubChem using a support vector machine with the signature molecular descriptor: Classification of factor XIa inhibitors. Journal of Molecular Graphics and Modelling, 27(4), 466-475.

4. Senger, S., & Leach, A. R. (2008). Chapter 11 SAR knowledge bases in drug discovery Dubois, J., Bourg, S., Vrain, C., & Morin-Allory, L. (2008). Collections of compounds - how to deal with them? Current Computer-Aided Drug Design, 4(3), 156-168.

5. Sharlow, E. R., Leimgruber, S., Yellow-Duke, A., Barrett, R., Wang, Q. J., & Lazo, J. S. (2008). Development, validation and implementation of immobilized metal affinity for phosphochemicals (IMAP)-based high-throughput screening assays for low-molecular-weight compound libraries. Nature Protocols, 3(8), 1350-1363.

6. McDonald, P. R., Roy, A., Tylor, B., Price, A., Sittampalam, S., Weir, S., et al. (2008). High throughput screening in academia - drug discovery initiatives at the university of kansas. Drug Discovery World, 9(4), 59-76.

7. Conn, P. J., & Roth, B. L. (2008). Opportunities and challenges of psychiatric drug discovery: Roles for scientists in academic, industry, and government settings. Neuropsychopharmacology, 33(9), 2048-2060.

8. Johnston, P. A., Soares, K. M., Shinde, S. N., Foster, C. A., Shun, T. Y., Takyi, H. K., et al. (2008). Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents. Assay and Drug Development Technologies, 6(4), 505-518. Jensen, N. H., & Roth, B. L. (2008). Massively parallel screening of the receptorome. Combinatorial Chemistry and High Throughput Screening, 11(6), 420-426.

9. Hur, J., & Wild, D. J. (2008). PubChemSR: A search and retrieval tool for PubChem. Chemistry Central Journal, 2(1)

10. Madoux, F., Li, X., Chase, P., Zastrow, G., Cameron, M. D., Conkright, J. J., et al. (2008). Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening. Molecular Pharmacology, 73(6), 1776-1784.

11. Cloutier, L. M., & Sirois, S. (2008). Bayesian versus frequentist statistical modeling: A debate for hit selection from HTS campaigns. Drug Discovery Today, 13(11-12), 536-542.

12. Rishton, G. M. (2008). Molecular diversity in the context of leadlikeness: Compound properties that enable effective biochemical screening. Current Opinion in Chemical Biology, 12(3), 340-351.

13. Judson, R., Elloumi, F., Woodrow, R. W., Li, Z., & Shah, I. (2008). A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model. BMC Bioinformatics, 9

14. Brochu, J. -., Prakesch, M., Enright, G. D., Leek, D. M., & Arya, P. (2008). Reagent-based, modular, tandem michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures. Journal of Combinatorial Chemistry, 10(3), 405-420.

15. Engel, S., Skoumbourdis, A. P., Childress, J., Neumann, S., Deschamps, J. R., Thomas, C. J., et al. (2008). A virtual screen for diverse ligands: Discovery of selective G protein-coupled receptor antagonists. Journal of the American Chemical Society, 130(15), 5115-5123.

16. Ivinson, A. J., Lane, R., May, P. C., Hosford, D. A., Carrillo, M. C., & Siemers, E. R. (2008). Partnership between academia and industry for drug discovery in alzheimer’s disease. Alzheimer’s and Dementia, 4(2), 80-88.

17. Houck, K. A., & Kavlock, R. J. (2008). Understanding mechanisms of toxicity: Insights from drug discovery research. Toxicology and Applied Pharmacology, 227(2), 163-178.

18. Richard, A. M., Yang, C., & Judson, R. S. (2008). Toxicity data informatics: Supporting a new paradigm for toxicity prediction. Toxicology Mechanisms and Methods, 18(2-3), 103-118.

19. Schröter, T., Minond, D., Weiser, A., Dao, C., Habel, J., Spicer, T., et al. (2008). Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of rho-kinase II (ROCK-II). Journal of Biomolecular Screening, 13(1), 17-28.

20. Faulon, J. -., Misra, M., Martin, S., Sale, K., & Sapra, R. (2008). Genome scale enzyme - metabolite and drug - target interaction predictions using the signature molecular descriptor. Bioinformatics, 24(2), 225-233.

21. Camp, D., Avery, V., Street, I., & Quinn, R. J. (2007). Progress toward establishing an open access molecular screening capability in the australasian region. ACS Chemical Biology, 2(12), 764-767.

22. Huryn, D. M., & Cosford, N. D. P. (2007). Chapter 26 the molecular libraries screening center network (MLSCN): Identifying chemical probes of biological systems

23. Scior, T., Bernard, P., Medina-Franco, J. L., & Maggiora, G. M. (2007). Large compound databases for structure-activity relationships studies in drug discovery. Mini-Reviews in Medicinal Chemistry, 7(8), 851-860.

24. Oprea, T. I., Tropsha, A., Faulon, J. -., & Rintoul, M. D. (2007). Systems chemical biology. Nature Chemical Biology, 3(8), 447-450.

25. Kawasumi, M., & Nghiem, P. (2007). Chemical genetics: Elucidating biological systems with small-molecule compounds. Journal of Investigative Dermatology, 127(7), 1577-1584.

26. Agrafiotis, D. K., Bandyopadhyay, D., Wegner, J. K., & Van Vlijmen, H. (2007). Recent advances in chemoinformatics. Journal of Chemical Information and Modeling, 47(4), 1279-1293.

27. Johnston, P. A., Foster, C. A., Tong, Y. S., Skoko, J. J., Shinde, S., Wipf, P., et al. (2007). Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual-specificity protein phosphatase inhibitors. Assay and Drug Development Technologies, 5(3), 319-332.

28. Adelman, D. E., & Deangelis, K. L. (2007). Patent metrics: The mismeasure of innovation in the biotech patent debate. Texas Law Review, 85(7), 1677-1744.

29. Tierno, M. B., Johnston, P. A., Foster, C., Skoko, J. J., Shinde, S. N., Shun, T. Y., et al. (2007). Development and optimization of high-throughput in vitro protein phosphatase screening assays. Nature Protocols, 2(5), 1134-1144.

30. Camp, D. (2007). Establishment of an open access compound management facility in australia to stimulate applied, basic and translational biomedical research. Drug Discovery World, 8(2), 61-64+66.

31. Sakurai, A., Kurata, A., Onishi, Y., Hirano, H., & Ishikawa, T. (2007). Prediction of drug-induced intrahepatic cholestasis: In vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump. Expert Opinion on Drug Safety, 6(1), 71-86.

32. Dix, D. J., Houck, K. A., Martin, M. T., Richard, A. M., Setzer, R. W., & Kavlock, R. J. (2007). The toxcast program for prioritizing toxicity testing of environmental chemicals. Toxicological Sciences, 95(1), 5-12.

33. Taussig, M. J., Stoevesandt, O., Borrebaeck, C. A. K., Bradbury, A. R., Cahill, D., Cambillau, C., et al. (2007). ProteomeBinders: Planning a european resource of affinity reagents for analysis of the human proteome. Nature Methods, 4(1), 13-17.

34. Oprea, T. I., Allu, T. K., Fara, D. C., Rad, R. F., Ostopovici, L., & Bologa, C. G. (2007). Lead-like, drug-like or “pub-like”: How different are they? Journal of Computer-Aided Molecular Design, 21(1-3), 113-119.

35. Oprea, T. I., & Tropsha, A. (2006). Target, chemical and bioactivity databases - integration is key. Drug Discovery Today: Technologies, 3(4), 357-365.

36. De Haro, L., & Panda, S. (2006). Systems biology of circadian rhythms: An outlook. Journal of Biological Rhythms, 21(6), 507-518.

37. Uga, H., Kuramori, C., Ohta, A., Tsuboi, Y., Tanaka, H., Hatakeyama, M., et al. (2006). A new mechanism of methotrexate action revealed by target screening with affinity beads. Molecular Pharmacology, 70(5), 1832-1839.

38. Richard, A. M. (2006). Future of toxicology-predictive toxicology: An expanded view of “chemical toxicity”. Chemical Research in Toxicology, 19(10), 1257-1262.

39. Lazo, J. S. (2006). Roadmap or roadkill: A pharmacologist’s analysis of the NIH molecular libraries initiative. Molecular Interventions, 6(5), 240-243

40. Prakesch, M., Sharma, U., Sharma, M., Khadem, S., Leek, D. M., & Arya, P. (2006). Part 1. modular approach to obtaining diverse tetrahydroquinoline-derived polycyclic skeletons for use in high-throughput generation of natural-product-like chemical probes. Journal of Combinatorial Chemistry, 8(5), 715-734.

41. Sharma, U., Srivastava, S., Prakesch, M., Sharma, M., Leek, D. M., & Arya, P. (2006). Part 2: Building diverse natural-product-like architectures from a tetrahydroaminoquinoline scaffold. modular solution- and solid-phase approaches for use in high-throughput generation of chemical probes. Journal of Combinatorial Chemistry, 8(5), 735-761.

42. Lipinski, C. A. (2006). The anti-intellectual effects of intellectual property. Current Opinion in Chemical Biology, 10(4), 380-383.

43. Irwin, J. J. (2006). How good is your screening library? Current Opinion in Chemical Biology, 10(4), 352-356.

44. Paolini, G. V., Shapland, R. H. B., Van Hoorn, W. P., Mason, J. S., & Hopkins, A. L. (2006). Global mapping of pharmacological space. Nature Biotechnology, 24(7), 805-815.

45. Willighagen, E. L., Wehrens, R., & Buydens, L. M. C. (2006). Molecular chemometrics. Critical Reviews in Analytical Chemistry, 36(3-4), 189-198.

46. Wild, D. J., & Wiggins, G. D. (2006). Challenges for chemoinformatics education in drug discovery. Drug Discovery Today, 11(9-10), 436-439.

47. Hirano, H., Kurata, A., Onishi, Y., Sakurai, A., Saito, H., Nakagawa, H., et al. (2006). High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis. Molecular Pharmaceutics, 3(3), 252-265.

48. Beller, M., & Oliver, B. (2006). One hundred years of high-throughput drosophila research. Chromosome Research, 14(4), 349-362.

49. Richard, A. M., Gold, L. S., & Nicklaus, M. C. (2006). Chemical structure indexing of toxicity data on the internet: Moving toward a flat world. Current Opinion in Drug Discovery and Development, 9(3), 314-325.

50. Krier, M., Bret, G., & Rognan, D. (2006). Assessing the scaffold diversity of screening libraries. Journal of Chemical Information and Modeling, 46(2), 512-524.

51. Choi, Y., Shimogawa, H., Murakami, K., Ramdas, L., Zhang, W., Qin, J., et al. (2006). Chemical genetic identification of the IGF-linked pathway that is mediated by STAT6 and MFP2. Chemistry and Biology, 13(3), 241-249.