| | This journal provides immediate access to some articles. Other Issues: previous | next | latest | archiveLetters Winnowing the archaeological evidence for domesticated sunflower in pre-Columbian Mesoamerica Bruce D. Smith PMCID: PMC2492492 Molecular evidence and the origin of the domesticated sunflower Loren Rieseberg and John M. Burke PMCID: PMC2492512 A lack of linguistic evidence for domesticated sunflower in pre-Columbian Mesoamerica Cecil H. Brown PMCID: PMC2492503 How old is the sunflower in Mexico? Charles B. Heiser PMCID: PMC2492500 Reply to Rieseberg and Burke, Heiser, Brown, and Smith: Molecular, linguistic, and archaeological evidence for domesticated sunflower in pre-Columbian Mesoamerica David L. Lentz, Mary DeLand Pohl, and Robert Bye PMCID: PMC2492516 This Week in PNAS Proc Natl Acad Sci U S A. 2008 July 29; 105(30): 10271–10272. doi: 10.1073/iti3008105.PMCID: PMC2492481 Commentaries Sexual orientation and its basis in brain structure and function Dick F. Swaab PMCID: PMC2492513 Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek Gordon J. Freeman PMCID: PMC2492504 The contrasting role of B7-H3 Kimberly A. Hofmeyer, Anjana Ray, and Xingxing Zang PMCID: PMC2492485 Physical Sciences Applied Physical Sciences Protecting residential care facilities from pandemic influenza M. Nuño, T. A. Reichert, G. Chowell, and A. B. Gumel PMCID: PMC2492509 Chemistry UV excitation of single DNA and RNA strands produces high yields of exciplex states between two stacked bases Tomohisa Takaya, Charlene Su, Kimberly de La Harpe, Carlos E. Crespo-Hernández, and Bern Kohler PMCID: PMC2492510 Environmental Sciences Variability in morphology, hygroscopicity, and optical properties of soot aerosols during atmospheric processing Renyi Zhang, Alexei F. Khalizov, Joakim Pagels, Dan Zhang, Huaxin Xue, and Peter H. McMurry PMCID: PMC2478695 Geology Calculation of site-specific carbon-isotope fractionation in pedogenic oxide minerals James R. Rustad and Piotr Zarzycki PMCID: PMC2475500 Biological Sciences Anthropology From the Cover:
Indo-European and Asian origins for Chilean and Pacific chickens revealed by mtDNA Jaime Gongora, Nicolas J. Rawlence, Victor A. Mobegi, Han Jianlin, Jose A. Alcalde, Jose T. Matus, Olivier Hanotte, Chris Moran, Jeremy J. Austin, Sean Ulm, Atholl J. Anderson, Greger Larson, and Alan Cooper PMCID: PMC2492461 Applied Biological Sciences Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load Dominika M. Wiktor-Brown, Hyuk-Sang Kwon, Yoon Sung Nam, Peter T. C. So, and Bevin P. Engelward PMCID: PMC2492490 Biochemistry High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage Sabine S. Lange, David L. Mitchell, and Karen M. Vasquez PMCID: PMC2492475 The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae Zhiqiang Chen, Christian Speck, Patricia Wendel, Chunyan Tang, Bruce Stillman, and Huilin Li PMCID: PMC2480615 RNA, but not protein partners, is directly responsible for translational silencing by a bacterial Hfq-binding small RNA Kimika Maki, Kanako Uno, Teppei Morita, and Hiroji Aiba PMCID: PMC2492515 Mechanism for alternating access in neurotransmitter transporters Lucy R. Forrest, Yuan-Wei Zhang, Miriam T. Jacobs, Joan Gesmonde, Li Xie, Barry H. Honig, and Gary Rudnick PMCID: PMC2480614 Evolution of sequence specificity in a restriction endonuclease by a point mutation Matheshwaran Saravanan, Kommireddy Vasu, and Valakunja Nagaraja PMCID: PMC2492507 Crystal structure of the cell wall anchor domain of MotB, a stator component of the bacterial flagellar motor: Implications for peptidoglycan recognition Anna Roujeinikova PMCID: PMC2492448 Biophysics UV excitation of single DNA and RNA strands produces high yields of exciplex states between two stacked bases Tomohisa Takaya, Charlene Su, Kimberly de La Harpe, Carlos E. Crespo-Hernández, and Bern Kohler PMCID: PMC2492510 Systems analysis of the single photon response in invertebrate photoreceptors Alain Pumir, Jennifer Graves, Rama Ranganathan, and Boris I. Shraiman PMCID: PMC2492478 Targeted rescue of a destabilized mutant of p53 by an in silico screened drug Frank M. Boeckler, Andreas C. Joerger, Gaurav Jaggi, Trevor J. Rutherford, Dmitry B. Veprintsev, and Alan R. Fersht PMCID: PMC2492497 Conformational dynamics of an intact virus: Order parameters for the coat protein of Pf1 bacteriophage Justin L. Lorieau, Loren A. Day, and Ann E. McDermott PMCID: PMC2492469 Reverse actin sliding triggers strong myosin binding that moves tropomyosin T. I. Bekyarova, M. C. Reedy, B. A. J. Baumann, R. T. Tregear, A. Ward, U. Krzic, K. M. Prince, R. J. Perz-Edwards, M. Reconditi, D. Gore, T. C. Irving, and M. K. Reedy PMCID: PMC2492518 Application of a polarizable force field to calculations of relative protein–ligand binding affinities Oleg Khoruzhii, Alexander G. Donchev, Nikolay Galkin, Alexei Illarionov, Mikhail Olevanov, Vladimir Ozrin, Cary Queen, and Vladimir Tarasov PMCID: PMC2492491 Extracting function from a β-trefoil folding motif Shachi Gosavi, Paul C. Whitford, Patricia A. Jennings, and José N. Onuchic PMCID: PMC2492465 Insights into protein flexibility: The relationship between normal modes and conformational change upon protein–protein docking Sara E. Dobbins, Victor I. Lesk, and Michael J. E. Sternberg PMCID: PMC2475499 Cell Biology Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity Motoaki Ohtsubo, Shin'ichiro Yasunaga, Yoshinori Ohno, Miyuki Tsumura, Satoshi Okada, Nobutsune Ishikawa, Kenichiro Shirao, Akira Kikuchi, Hideo Nishitani, Masao Kobayashi, and Yoshihiro Takihara PMCID: PMC2492514 Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3 Andreas Traweger, Giselle Wiggin, Lorne Taylor, Stephen A. Tate, Pavel Metalnikov, and Tony Pawson PMCID: PMC2475498 Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations Alyson W. MacInnes, Adam Amsterdam, Charles A. Whittaker, Nancy Hopkins, and Jacqueline A. Lees PMCID: PMC2492501 Developmental Biology Genetic control of floral zygomorphy in pea (Pisum sativum L.) Zheng Wang, Yonghai Luo, Xin Li, Liping Wang, Shilei Xu, Jun Yang, Lin Weng, Shusei Sato, Satoshi Tabata, Mike Ambrose, Catherine Rameau, Xianzhong Feng, Xiaohe Hu, and Da Luo PMCID: PMC2492476 Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells David T. Breault, Irene M. Min, Diana L. Carlone, Loredana G. Farilla, Dana M. Ambruzs, Daniel E. Henderson, Selma Algra, Robert K. Montgomery, Amy J. Wagers, and Nicholas Hole PMCID: PMC2492454 Ecology Chronic intake of fermented floral nectar by wild treeshrews Frank Wiens, Annette Zitzmann, Marc-André Lachance, Michel Yegles, Fritz Pragst, Friedrich M. Wurst, Dietrich von Holst, Saw Leng Guan, and Rainer Spanagel PMCID: PMC2492458 Environmental regulation in a network of simulated microbial ecosystems Hywel T. P. Williams and Timothy M. Lenton PMCID: PMC2492457 Whole-cell response of the pennate diatom Phaeodactylum tricornutum to iron starvation Andrew E. Allen, Julie LaRoche, Uma Maheswari, Markus Lommer, Nicolas Schauer, Pascal J. Lopez, Giovanni Finazzi, Alisdair R. Fernie, and Chris Bowler PMCID: PMC2492447 Environmental Sciences Bleaching susceptibility and mortality of corals are determined by fine-scale differences in symbiont type E. M. Sampayo, T. Ridgway, P. Bongaerts, and O. Hoegh-Guldberg PMCID: PMC2492480 Poorly cemented coral reefs of the eastern tropical Pacific: Possible insights into reef development in a high-CO2 world Derek P. Manzello, Joan A. Kleypas, David A. Budd, C. Mark Eakin, Peter W. Glynn, and Chris Langdon PMCID: PMC2492517 Mangroves in the Gulf of California increase fishery yields Octavio Aburto-Oropeza, Exequiel Ezcurra, Gustavo Danemann, Víctor Valdez, Jason Murray, and Enric Sala PMCID: PMC2492483 From the Cover:
Amazon River enhances diazotrophy and carbon sequestration in the tropical North Atlantic Ocean A. Subramaniam, P. L. Yager, E. J. Carpenter, C. Mahaffey, K. Björkman, S. Cooley, A. B. Kustka, J. P. Montoya, S. A. Sañudo-Wilhelmy, R. Shipe, and D. G. Capone PMCID: PMC2480616 Evolution Evolution of flowering decisions in a stochastic, density-dependent environment C. J. E. Metcalf, K. E. Rose, D. Z. Childs, A. W. Sheppard, P. J. Grubb, and M. Rees PMCID: PMC2492471 Genetics Sperm cross-over activity in regions of the human genome showing extreme breakdown of marker association Adam J. Webb, Ingrid L. Berg, and Alec Jeffreys PMCID: PMC2483235 Immunology The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading David R. Peaper and Peter Cresswell PMCID: PMC2483232 From the Cover:
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2 Eszter Lázár-Molnár, Qingrong Yan, Erhu Cao, Udupi Ramagopal, Stanley G. Nathenson, and Steven C. Almo PMCID: PMC2492495 A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys Sampa Santra, Bette T. Korber, Mark Muldoon, Dan H. Barouch, Gary J. Nabel, Feng Gao, Beatrice H. Hahn, Barton F. Haynes, and Norman L. Letvin PMCID: PMC2483234 From the Cover:
Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses Masaaki Hashiguchi, Hiroko Kobori, Patcharee Ritprajak, Yosuke Kamimura, Haruo Kozono, and Miyuki Azuma PMCID: PMC2492502 Molecular and cellular signatures of human vaccine adjuvants F. Mosca, E. Tritto, A. Muzzi, E. Monaci, F. Bagnoli, C. Iavarone, D. O'Hagan, R. Rappuoli, and E. De Gregorio PMCID: PMC2483233 Endothelial nitric oxide synthase regulates N-Ras activation on the Golgi complex of antigen-stimulated T cells Sales Ibiza, Andrea Pérez-Rodríguez, Ángel Ortega, Antonio Martínez-Ruiz, Olga Barreiro, Carlota A. García-Domínguez, Víctor M. Víctor, Juan V. Esplugues, José M. Rojas, Francisco Sánchez-Madrid, and Juan M. Serrador PMCID: PMC2492470 Medical Sciences Circulating microRNAs as stable blood-based markers for cancer detection Patrick S. Mitchell, Rachael K. Parkin, Evan M. Kroh, Brian R. Fritz, Stacia K. Wyman, Era L. Pogosova-Agadjanyan, Amelia Peterson, Jennifer Noteboom, Kathy C. O'Briant, April Allen, Daniel W. Lin, Nicole Urban, Charles W. Drescher, Beatrice S. Knudsen, Derek L. Stirewalt, Robert Gentleman, Robert L. Vessella, Peter S. Nelson, Daniel B. Martin, and Muneesh Tewari PMCID: PMC2492472 ATF6α-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo Denis M. Schewe and Julio A. Aguirre-Ghiso PMCID: PMC2492459 Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1 Robert Eferl, Peter Hasselblatt, Martina Rath, Helmut Popper, Rainer Zenz, Vukoslav Komnenovic, Maria-Helena Idarraga, Lukas Kenner, and Erwin F. Wagner PMCID: PMC2492511 Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249 Ronald S. Veazey, Thomas A. Ketas, Per Johan Klasse, Donna K. Davison, Morgan Singletary, Linda C. Green, Michael L. Greenberg, and John P. Moore PMCID: PMC2492474 S-nitrosylation/activation of COX-2 mediates NMDA neurotoxicity Jing Tian, Sangwon F. Kim, Lynda Hester, and Solomon H. Snyder PMCID: PMC2492460 Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release Jez G. Carlton, Monica Agromayor, and Juan Martin-Serrano PMCID: PMC2492449 In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of β-thalassemia Annarita Miccio, Rossano Cesari, Francesco Lotti, Claudia Rossi, Francesca Sanvito, Maurilio Ponzoni, Samantha J. E. Routledge, Cheok-Man Chow, Michael N. Antoniou, and Giuliana Ferrari PMCID: PMC2492493 RIG-I plays a critical role in negatively regulating granulocytic proliferation Nan-Nan Zhang, Shu-Hong Shen, Lin-Jia Jiang, Wu Zhang, Hong-Xin Zhang, Yue-Ping Sun, Xian-Yang Li, Qiu-Hua Huang, Bao-Xue Ge, Sai-Juan Chen, Zhu-Gang Wang, Zhu Chen, and Jiang Zhu PMCID: PMC2492484 Microbiology Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry Ulrike E. Maurer, Beate Sodeik, and Kay Grünewald PMCID: PMC2492464 D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein Jiří Vlach, Jan Lipov, Michaela Rumlová, Václav Veverka, Jan Lang, Pavel Srb, Zdeněk Knejzlík, Iva Pichová, Eric Hunter, Richard Hrabal, and Tomáš Ruml PMCID: PMC2492450 A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration Melina A. Agosto, Kimberly S. Myers, Tijana Ivanovic, and Max L. Nibert PMCID: PMC2492467 ATP negatively regulates the initiator protein of Vibrio cholerae chromosome II replication Stéphane Duigou, Yoshiharu Yamaichi, and Matthew K. Waldor PMCID: PMC2492486 Metagenomic signatures of the Peru Margin subseafloor biosphere show a genetically distinct environment Jennifer F. Biddle, Sorel Fitz-Gibbon, Stephan C. Schuster, Jean E. Brenchley, and Christopher H. House PMCID: PMC2492506 Neuroscience INAUGURAL ARTICLE by a Recently Elected Academy Member: Parallel memory processing by the CA1 region of the dorsal hippocampus and the basolateral amygdala Martín Cammarota, Lia R. Bevilaqua, Janine I. Rossato, Ramón H. Lima, Jorge H. Medina, and Iván Izquierdo PMCID: PMC2492498 From the Cover:
Impact of overactive bladder on the brain: Central sequelae of a visceral pathology Elizabeth Rickenbacher, Madelyn A. Baez, Lyman Hale, Steven C. Leiser, Stephen A. Zderic, and Rita J. Valentino PMCID: PMC2478694 A γ-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains Patricia Spilman, Pierre Lessard, Mamta Sattavat, Clarissa Bush, Thomas Tousseyn, Eric J. Huang, Kurt Giles, Todd Golde, Pritam Das, Abdul Fauq, Stanley B. Prusiner, and Stephen J. DeArmond PMCID: PMC2492499 Rapid encoding of new information alters the profile of plasticity-related mRNA transcripts in the hippocampal CA3 region Rebecca P. Haberman, Hongjoo J. Lee, Carlo Colantuoni, Ming Teng Koh, and Michela Gallagher PMCID: PMC2492487 High-field fMRI unveils orientation columns in humans Essa Yacoub, Noam Harel, and Kâmil Uğurbil PMCID: PMC2492463 Physiology Melanin-concentrating hormone as a mediator of intestinal inflammation Efi Kokkotou, Alan C. Moss, Daniel Torres, Iordanes Karagiannides, Adam Cheifetz, Sumei Liu, Michael O'Brien, Eleftheria Maratos-Flier, and Charalabos Pothoulakis PMCID: PMC2492477 Plant Biology Chloroplast Fe(III) chelate reductase activity is essential for seedling viability under iron limiting conditions Jeeyon Jeong, Christopher Cohu, Loubna Kerkeb, Marinus Pilon, Erin L. Connolly, and Mary Lou Guerinot PMCID: PMC2492473 Population Biology Protecting residential care facilities from pandemic influenza M. Nuño, T. A. Reichert, G. Chowell, and A. B. Gumel PMCID: PMC2492509 Social Sciences Environmental Sciences Global cost estimates of reducing carbon emissions through avoided deforestation Georg Kindermann, Michael Obersteiner, Brent Sohngen, Jayant Sathaye, Kenneth Andrasko, Ewald Rametsteiner, Bernhard Schlamadinger, Sven Wunder, and Robert Beach PMCID: PMC2483236 Corrections Correction for Zavala et al., Anthropogenic increase in carbon dioxide compromises plant defense against invasive insects PMCID: PMC2492488 Corrects:Jorge A. Zavala, et al. Anthropogenic increase in carbon dioxide compromises plant defense against invasive insects. Proc Natl Acad Sci U S A. 2008 April 1; 105(13): 5129–5133. Correction for Johnson et al., Ancient bacteria show evidence of DNA repair PMCID: PMC2492451 Corrects:Sarah Stewart Johnson, et al. Ancient bacteria show evidence of DNA repair. Proc Natl Acad Sci U S A. 2007 September 4; 104(36): 14401–14405. Correction for Speiser et al., Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen PMCID: PMC2492468 Corrects:Daniel E. Speiser, et al. Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen. Proc Natl Acad Sci U S A. 2008 March 11; 105(10): 3849–3854. Correction for Tomschik et al., Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer PMCID: PMC2492479 Corrects:Miroslav Tomschik, et al. Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer. Proc Natl Acad Sci U S A. 2005 March 1; 102(9): 3278–3283. |
