| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 September 25; 104(39): 15169–15170. doi: 10.1073/iti3907104.PMCID: PMC2000552 Commentary Mitochondria control calcium entry at the immunological synapse Scott A. Oakes PMCID: PMC2000514 Profile Profile of Ding-Shinn Chen Philip Downey PMCID: PMC2000525 Going Beyond Panaceas Special Feature Research Articles Community-based conservation in a globalized world Fikret Berkes PMCID: PMC2000555 Panaceas, uncertainty, and the robust control framework in sustainability science John M. Anderies, Armando A. Rodriguez, Marco A. Janssen, and Oguzhan Cifdaloz PMCID: PMC2000534 Beyond panaceas in water institutions Ruth Meinzen-Dick PMCID: PMC2000530 From the Cover: Going Beyond Panaceas Special Feature:
Panaceas and diversification of environmental policy William A. Brock and Stephen R. Carpenter PMCID: PMC2000546 The precursors of governance in the Maine lobster fishery James Wilson, Liying Yan, and Carl Wilson PMCID: PMC2000522 Drivers of reforestation in human-dominated forests Harini Nagendra PMCID: PMC2000538 Perspectives Going beyond panaceas Elinor Ostrom, Marco A. Janssen, and John M. Anderies PMCID: PMC2000490 Future challenges Charles Perrings PMCID: PMC2000541 A diagnostic approach for going beyond panaceas Elinor Ostrom PMCID: PMC2000497 Physical Sciences Applied Physical Sciences Extracting the hierarchical organization of complex systems Marta Sales-Pardo, Roger Guimerà, André A. Moreira, and Luís A. Nunes Amaral PMCID: PMC2000510 Electrostatic interactions in phospholipid membranes revealed by coherent 2D IR spectroscopy V. V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A. M. Papini, S. Mukamel, and R. Righini PMCID: PMC2000491 Chemistry Dehydration-driven solvent exposure of hydrophobic surfaces as a driving force in peptide folding Isabella Daidone, Martin B. Ulmschneider, Alfredo Di Nola, Andrea Amadei, and Jeremy C. Smith PMCID: PMC2000556 Synthesis of crystals with a programmable kinetic barrier to nucleation Rebecca Schulman and Erik Winfree PMCID: PMC1986573 Environmental Sciences Changes in climate and land use have a larger direct impact than rising CO2 on global river runoff trends Shilong Piao, Pierre Friedlingstein, Philippe Ciais, Nathalie de Noblet-Ducoudré, David Labat, and Sönke Zaehle PMCID: PMC1978487 Identification of human-induced changes in atmospheric moisture content B. D. Santer, C. Mears, F. J. Wentz, K. E. Taylor, P. J. Gleckler, T. M. L. Wigley, T. P. Barnett, J. S. Boyle, W. Brüggemann, N. P. Gillett, S. A. Klein, G. A. Meehl, T. Nozawa, D. W. Pierce, P. A. Stott, W. M. Washington, and M. F. Wehner PMCID: PMC1986574 Physics Quantum spin correlations through the superconducting-to-normal phase transition in electron-doped superconducting Pr0.88LaCe0.12CuO4-δ Stephen D. Wilson, Shiliang Li, Jun Zhao, Gang Mu, Hai-Hu Wen, Jeffrey W. Lynn, Paul G. Freeman, Louis-Pierre Regnault, Klaus Habicht, and Pengcheng Dai PMCID: PMC2000518 Quantum dynamics and entanglement of spins on a square lattice N. B. Christensen, H. M. Rønnow, D. F. McMorrow, A. Harrison, T. G. Perring, M. Enderle, R. Coldea, L. P. Regnault, and G. Aeppli PMCID: PMC2000527 Myosin V stepping mechanism Giovanni Cappello, Paolo Pierobon, Clémentine Symonds, Lorenzo Busoni, J. Christof, M. Gebhardt, Matthias Rief, and Jacques Prost PMCID: PMC2000544 Biological Sciences Agricultural Sciences Improvement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance gene Aarati Karaba, Shital Dixit, Raffaella Greco, Asaph Aharoni, Kurniawan R. Trijatmiko, Nayelli Marsch-Martinez, Arjun Krishnan, Karaba N. Nataraja, Makarla Udayakumar, and Andy Pereira PMCID: PMC1986572 Anthropology From the Cover:
Ancient DNA, pig domestication, and the spread of the Neolithic into Europe Greger Larson, Umberto Albarella, Keith Dobney, Peter Rowley-Conwy, Jörg Schibler, Anne Tresset, Jean-Denis Vigne, Ceiridwen J. Edwards, Angela Schlumbaum, Alexandru Dinu, Adrian Bălăçsescu, Gaynor Dolman, Antonio Tagliacozzo, Ninna Manaseryan, Preston Miracle, Louise Van Wijngaarden-Bakker, Marco Masseti, Daniel G. Bradley, and Alan Cooper PMCID: PMC1976408 Applied Biological Sciences Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation GuoQiang Sun, Ruth T. Yu, Ronald M. Evans, and Yanhong Shi PMCID: PMC2000559 Biochemistry Emergence of a fast-reacting ribozyme that is capable of undergoing continuous evolution Sarah B. Voytek and Gerald F. Joyce PMCID: PMC2000504 Structural determination of wild-type lactose permease Lan Guan, Osman Mirza, Gillian Verner, So Iwata, and H. Ronald Kaback PMCID: PMC2000551 Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome Jiqiang Ling, Hervé Roy, Daoming Qin, Mary Anne T. Rubio, Juan D. Alfonzo, Kurt Fredrick, and Michael Ibba PMCID: PMC2000536 Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event Rashna Bhandari, Adolfo Saiardi, Yousef Ahmadibeni, Adele M. Snowman, Adam C. Resnick, Troels Z. Kristiansen, Henrik Molina, Akhilesh Pandey, J. Kent Werner, Jr., Krishna R. Juluri, Yong Xu, Glenn D. Prestwich, Keykavous Parang, and Solomon H. Snyder PMCID: PMC2000531 From the Cover:
Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC Katherine S. Ryan, Annaleise R. Howard-Jones, Michael J. Hamill, Sean J. Elliott, Christopher T. Walsh, and Catherine L. Drennan PMCID: PMC2000502 Anatomy of energetic changes accompanying urea-induced protein denaturation Matthew Auton, Luis Marcelo F. Holthauzen, and D. Wayne Bolen PMCID: PMC2000523 Biophysics Dehydration-driven solvent exposure of hydrophobic surfaces as a driving force in peptide folding Isabella Daidone, Martin B. Ulmschneider, Alfredo Di Nola, Andrea Amadei, and Jeremy C. Smith PMCID: PMC2000556 Electrostatic interactions in phospholipid membranes revealed by coherent 2D IR spectroscopy V. V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A. M. Papini, S. Mukamel, and R. Righini PMCID: PMC2000491 Myosin V stepping mechanism Giovanni Cappello, Paolo Pierobon, Clémentine Symonds, Lorenzo Busoni, J. Christof, M. Gebhardt, Matthias Rief, and Jacques Prost PMCID: PMC2000544 Structural insight into Ca2+ specificity in tetrameric cation channels Amer Alam, Ning Shi, and Youxing Jiang PMCID: PMC2000519 Simulating replica exchange simulations of protein folding with a kinetic network model Weihua Zheng, Michael Andrec, Emilio Gallicchio, and Ronald M. Levy PMCID: PMC2000486 Principal component analysis of the pH-dependent conformational transitions of bovine β-lactoglobulin monitored by heteronuclear NMR Kazumasa Sakurai and Yuji Goto PMCID: PMC2000507 Cell Biology The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function Gregory D. Fairn, Amy J. Curwin, Christopher J. Stefan, and Christopher R. McMaster PMCID: PMC2000554 Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization Xuehui Chen, Thomas Doohun Kim, Christopher V. Carman, Li-Zhi Mi, Gang Song, and Timothy A. Springer PMCID: PMC2000496 IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs Katerina Tritsaris, Maja Myren, Sisse B. Ditlev, Martin V. Hübschmann, Ida van der Blom, Anker Jon Hansen, Uffe B. Olsen, Renhai Cao, Junhang Zhang, Tanghong Jia, Eric Wahlberg, Steen Dissing, and Yihai Cao PMCID: PMC1978488 Processing and function of CFTR-ΔF508 are species-dependent Lynda S. Ostedgaard, Christopher S. Rogers, Qian Dong, Christoph O. Randak, Daniel W. Vermeer, Tatiana Rokhlina, Philip H. Karp, and Michael J. Welsh PMCID: PMC1976592 Developmental Biology Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo Ute Schaeper, Regina Vogel, Jolanta Chmielowiec, Joerg Huelsken, Marta Rosario, and Walter Birchmeier PMCID: PMC2000540 The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors Adriano Flora, Jesus J. Garcia, Christina Thaller, and Huda Y. Zoghbi PMCID: PMC1978485 Evolution Metabolic rate does not calibrate the molecular clock Robert Lanfear, Jessica A. Thomas, John J. Welch, Thomas Brey, and Lindell Bromham PMCID: PMC2000532 Genetics A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin Chunmei Yang, Jinong Feng, Wenjia Song, Jicheng Wang, Becky Tsai, Yunwu Zhang, William A. Scaringe, Kathleen A. Hill, Paris Margaritis, Katherine A. High, and Steve S. Sommer PMCID: PMC2000501 Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis Rene Opavsky, Shih-Yin Tsai, Martin Guimond, Anjulie Arora, Jana Opavska, Brian Becknell, Michael Kaufmann, Nathaniel A. Walton, Julie A. Stephens, Soledad A. Fernandez, Natarajan Muthusamy, Dean W. Felsher, Pierluigi Porcu, Michael A. Caligiuri, and Gustavo Leone PMCID: PMC2000495 Global transcriptional responses to cisplatin in Dictyostelium discoideum identify potential drug targets Nancy Van Driessche, Hannah Alexander, Junxia Min, Adam Kuspa, Stephen Alexander, and Gad Shaulsky PMCID: PMC2000517 Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila Monica A. Rodriguez, Danielle Vermaak, Joshua J. Bayes, and Harmit S. Malik PMCID: PMC2000485 Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors Cynthia Kosinski, Vivian S. W. Li, Annie S. Y. Chan, Ji Zhang, Coral Ho, Wai Yin Tsui, Tsun Leung Chan, Randy C. Mifflin, Don W. Powell, Siu Tsan Yuen, Suet Yi Leung, and Xin Chen PMCID: PMC2000506 Immunology Wiskott–Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development Vinicius Cotta-de-Almeida, Lisa Westerberg, Michel H. Maillard, Dilek Onaldi, Heather Wachtel, Parool Meelu, Ung-il Chung, Ramnik Xavier, Frederick W. Alt, and Scott B. Snapper PMCID: PMC2000553 Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection Scott N. Mueller, Mehrdad Matloubian, Daniel M. Clemens, Arlene H. Sharpe, Gordon J. Freeman, Shivaprakash Gangappa, Christian P. Larsen, and Rafi Ahmed PMCID: PMC2000533 Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation Michael J. Nemeth, Lilia Topol, Stacie M. Anderson, Yingzi Yang, and David M. Bodine PMCID: PMC1986571 γc cytokines condition the progressive differentiation of CD4+ T cells Guillemette X. Masse, Erwan Corcuff, Hélène Strick-Marchand, Delphine Guy-Grand, Anna Tafuri-Bladt, Matthew L. Albert, Olivier Lantz, and James P. Di Santo PMCID: PMC2000521 Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance Sophie Brouard, Elaine Mansfield, Christophe Braud, Li Li, Magali Giral, Szu-chuan Hsieh, Dominique Baeten, Meixia Zhang, Joanna Ashton-Chess, Cécile Braudeau, Frank Hsieh, Alexandre Dupont, Annaik Pallier, Anne Moreau, Stéphanie Louis, Catherine Ruiz, Oscar Salvatierra, Jean-Paul Soulillou, and Minnie Sarwal PMCID: PMC2000539 Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells Margarida Almeida Santos, Leonor Morais Sarmento, Manuel Rebelo, Ana Agua Doce, Ivan Maillard, Alexis Dumortier, Helia Neves, Freddy Radtke, Warren S. Pear, Leonor Parreira, and Jocelyne Demengeot PMCID: PMC2000509 Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation Reinhard Obst, Hisse-Martien van Santen, Rachel Melamed, Alice O. Kamphorst, Christophe Benoist, and Diane Mathis PMCID: PMC2000557 Mathematics Shannon's monotonicity problem for free and classical entropy Dimitri Shlyakhtenko and With appendix by Hanne Schultz PMCID: PMC2000542 Medical Sciences PAS kinase is required for normal cellular energy balance Huai-Xiang Hao, Caleb M. Cardon, Wojtek Swiatek, Robert C. Cooksey, Tammy L. Smith, James Wilde, Sihem Boudina, E. Dale Abel, Donald A. McClain, and Jared Rutter PMCID: PMC2000499 Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells Hiroshi Tazawa, Naoto Tsuchiya, Masashi Izumiya, and Hitoshi Nakagama PMCID: PMC2000550 Nitric oxide induces CD4+CD25+ Foxp3− regulatory T cells from CD4+CD25− T cells via p53, IL-2, and OX40 Wanda Niedbala, Beilei Cai, Haiying Liu, Nick Pitman, Lynda Chang, and Foo Y. Liew PMCID: PMC1978217 MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells Steven J. Greco and Pranela Rameshwar PMCID: PMC2000543 From the Cover:
Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index Mark D. Erion, Edward E. Cable, Bruce R. Ito, Hongjian Jiang, James M. Fujitaki, Patricia D. Finn, Bao-Hong Zhang, Jinzhao Hou, Serge H. Boyer, Paul D. van Poelje, and David L. Linemeyer PMCID: PMC1978486 Microbiology Regulatory T cell-like responses in deer mice persistently infected with Sin Nombre virus Tony Schountz, Joseph Prescott, Ann C. Cogswell, Lauren Oko, Katy Mirowsky-Garcia, Alejandra P. Galvez, and Brian Hjelle PMCID: PMC2000535 Regulatory T cells enhance persistence of the zoonotic pathogen Seoul virus in its reservoir host Judith D. Easterbrook, M. Christine Zink, and Sabra L. Klein PMCID: PMC2000529 Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin Stefan Pukatzki, Amy T. Ma, Andrew T. Revel, Derek Sturtevant, and John J. Mekalanos PMCID: PMC2000545 Neuroscience Dmbx1 is essential in agouti-related protein action Wakako Fujimoto, Tetsuya Shiuchi, Takashi Miki, Yasuhiko Minokoshi, Yoshihisa Takahashi, Ayako Takeuchi, Kazuhiro Kimura, Masayuki Saito, Toshihiko Iwanaga, and Susumu Seino PMCID: PMC1976593 Rapid seasonal-like regression of the adult avian song control system Christopher K. Thompson, George E. Bentley, and Eliot A. Brenowitz PMCID: PMC2000488 Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus Agenor Limon, Jorge Mauricio Reyes-Ruiz, Fabrizio Eusebi, and Ricardo Miledi PMCID: PMC2000508 Resting-state networks in the infant brain Peter Fransson, Beatrice Skiöld, Sandra Horsch, Anders Nordell, Mats Blennow, Hugo Lagercrantz, and Ulrika Åden PMCID: PMC2000516 Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors Mika Nakamoto, Vijayalaxmi Nalavadi, Michael P. Epstein, Usha Narayanan, Gary J. Bassell, and Stephen T. Warren PMCID: PMC2000537 Pharmacology Phospholipase Cε is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation Simona Citro, Sundeep Malik, Emily A. Oestreich, Julie Radeff-Huang, Grant G. Kelley, Alan V. Smrcka, and Joan Heller Brown PMCID: PMC2000505 Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging Derek W. Bartlett, Helen Su, Isabel J. Hildebrandt, Wolfgang A. Weber, and Mark E. Davis PMCID: PMC1978218 Physiology Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate Xinliang Zhou, Zhenwei Su, Andriy Anishkin, W. John Haynes, Eric M. Friske, Stephen H. Loukin, Ching Kung, and Yoshiro Saimi PMCID: PMC2000494 Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function John W. Elrod, John W. Calvert, Joanna Morrison, Jeannette E. Doeller, David W. Kraus, Ling Tao, Xiangying Jiao, Rosario Scalia, Levente Kiss, Csaba Szabo, Hideo Kimura, Chi-Wing Chow, and David J. Lefer PMCID: PMC2000503 Plant Biology Genetic evidence for three unique components in primary cell-wall cellulose synthase complexes in Arabidopsis Staffan Persson, Alexander Paredez, Andrew Carroll, Hildur Palsdottir, Monika Doblin, Patricia Poindexter, Natalie Khitrov, Manfred Auer, and Chris R. Somerville PMCID: PMC2000526 Organization of cellulose synthase complexes involved in primary cell wall synthesis in Arabidopsis thaliana Thierry Desprez, Michal Juraniec, Elizabeth Faris Crowell, Hélène Jouy, Zaneta Pochylova, Francois Parcy, Herman Höfte, Martine Gonneau, and Samantha Vernhettes PMCID: PMC2000492 Evolution of asexual reproduction in leaves of the genus Kalanchoë Helena M. P. Garcês, Connie E. M. Champagne, Brad T. Townsley, Soomin Park, Rui Malhó, Maria C. Pedroso, John J. Harada, and Neelima R. Sinha PMCID: PMC2000513 Sustainability Science Drivers of reforestation in human-dominated forests Harini Nagendra PMCID: PMC2000538 Social Sciences Anthropology From the Cover:
Ancient DNA, pig domestication, and the spread of the Neolithic into Europe Greger Larson, Umberto Albarella, Keith Dobney, Peter Rowley-Conwy, Jörg Schibler, Anne Tresset, Jean-Denis Vigne, Ceiridwen J. Edwards, Angela Schlumbaum, Alexandru Dinu, Adrian Bălăçsescu, Gaynor Dolman, Antonio Tagliacozzo, Ninna Manaseryan, Preston Miracle, Louise Van Wijngaarden-Bakker, Marco Masseti, Daniel G. Bradley, and Alan Cooper PMCID: PMC1976408 Political Sciences Beyond panaceas in water institutions Ruth Meinzen-Dick PMCID: PMC2000530 Sustainability Science Community-based conservation in a globalized world Fikret Berkes PMCID: PMC2000555 Panaceas, uncertainty, and the robust control framework in sustainability science John M. Anderies, Armando A. Rodriguez, Marco A. Janssen, and Oguzhan Cifdaloz PMCID: PMC2000534 Beyond panaceas in water institutions Ruth Meinzen-Dick PMCID: PMC2000530 From the Cover: Going Beyond Panaceas Special Feature:
Panaceas and diversification of environmental policy William A. Brock and Stephen R. Carpenter PMCID: PMC2000546 The precursors of governance in the Maine lobster fishery James Wilson, Liying Yan, and Carl Wilson PMCID: PMC2000522 Drivers of reforestation in human-dominated forests Harini Nagendra PMCID: PMC2000538 Correction Correction for Moerner, Single-Molecule Chemistry and Biology Special Feature: New directions in single-molecule imaging and analysis PMCID: PMC2000558 Corrects: W. E. Moerner. New directions in single-molecule imaging and analysis. Proc Natl Acad Sci U S A. 2007 July 31; 104(31): 12596–12602. |
