Freeze-dried blood cells: therapeutic advance or laboratory curiosity?

Of archae and eo: what's in a name?

Integrating information at single synaptic connections.

Biomolecular folding in vacuo!!!(?)

Platelet von Willebrand factor in inherited and acquired bleeding disorders.

Visual motion perception.

Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications.

D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus.

Gas-phase folding and unfolding of cytochrome c cations.

Function of von Willebrand factor after crossed bone marrow transplantation between normal and von Willebrand disease pigs: effect on arterial thrombosis in chimeras.

DNA recombination is sufficient for retroviral transduction.

Total chemical synthesis of a ribozyme derived from a group I intron.

"Rattlesnake" structure of a filamentous plant RNA virus built of two capsid proteins.

Colocalization of calcium entry and exocytotic release sites in adrenal chromaffin cells.

Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove.

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus.

Radial and tangential dispersion patterns in the mouse retina are cell-class specific.

Association of a polynuclear iron-sulfur center with a mutant FNR protein enhances DNA binding.

Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps.

Core lipid structure is a major determinant of the oxidative resistance of low density lipoprotein.

Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast.

Sexual isolation in Drosophila melanogaster: a possible case of incipient speciation.

Ecological chaos in the wake of invasion.

Human autoantibody recognition of DNA.

IgE receptor-positive non-B/non-T cells dominate the production of interleukin 4 and interleukin 6 in immunized mice.

Aceruloplasminemia: molecular characterization of this disorder of iron metabolism.

Molecular cloning and characterization of chitinase genes from Candida albicans.

Rapid alteration of thalamocortical axon morphology follows peripheral damage in the neonatal rat.

Pancreatic digestive enzyme secretion in the rabbit: rapid cyclic variations in enzyme composition.

Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class.

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

Basis of guanylate cyclase activation by carbon monoxide.

Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.

Combination gene therapy for liver metastasis of colon carcinoma in vivo.

Promoter architecture in the flagellar regulon of Bacillus subtilis: high-level expression of flagellin by the sigma D RNA polymerase requires an upstream promoter element.

A cyclophilin from the polycentric anaerobic rumen fungus Orpinomyces sp. strain PC-2 is highly homologous to vertebrate cyclophilin B.

Activation of YRP kinase by v-Src and protein kinase C-mediated signal transduction pathways.

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

Strong natural selection causes microscale allozyme variation in a marine snail.

Fate of a redundant gamma-globin gene in the atelid clade of New World monkeys: implications concerning fetal globin gene expression.

Iontophoresis for modulation of cardiac drug delivery in dogs.

Evidence suggesting that the odortypes of pregnant women are a compound of maternal and fetal odortypes.

Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.

Two helices plus a linker: a small model substrate for eukaryotic RNase P.

The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake.

Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.

Distinct functions of SR proteins in recruitment of U1 small nuclear ribonucleoprotein to alternative 5' splice sites.

Chloroplast gene sequence data suggest a single origin of the predisposition for symbiotic nitrogen fixation in angiosperms.

A chemically diverse conducting polymer-based "electronic nose".

Kinetics of hydrogen bond breakage in the process of unfolding of ribonuclease A measured by pulsed hydrogen exchange.

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.

Effects of yeast DNA topoisomerase III on telomere structure.

Functional estrogen receptors in a human preosteoclastic cell line.

The rapid assembly of synaptic sites in photoreceptor terminals of the fly's optic lobe recovering from cold shock.

Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin.

Two forms of acetylcholine receptor gamma subunit in mouse muscle.

Endothelin 1 mediates ex vivo coronary vasoconstriction caused by exogenous and endogenous cytokines.

Ca(2+)-inhibitable adenylyl cyclase modulates pulmonary artery endothelial cell cAMP content and barrier function.

Use of Saccharomyces cerevisiae for patch-clamp analysis of heterologous membrane proteins: characterization of Kat1, an inward-rectifying K+ channel from Arabidopsis thaliana, and comparison with endogeneous yeast channels and carriers.

In vitro sulfotransferase activity of Rhizobium meliloti NodH protein: lipochitooligosaccharide nodulation signals are sulfated after synthesis of the core structure.

A random-walk/giant-loop model for interphase chromosomes.

Energy transfer and trapping in photosystem I reaction centers from cyanobacteria.

P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1.

Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription.

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

Genetic control of blood pressure and the angiotensinogen locus.

Substitution of a highly basic helix/loop sequence into the RNase H domain of human immunodeficiency virus reverse transcriptase restores its Mn(2+)-dependent RNase H activity.

Negative-acting factor and superantigen are separable activities of the mouse mammary tumor virus long terminal repeat.

Stimulation of T cells by antigen-presenting cells is kinetically controlled by antigenic peptide binding to major histocompatibility complex class II molecules.

Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.

Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs.

Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.

A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects.

Benzodiazepine receptors mediate regional blood flow changes in the living human brain.

Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

Decreased expression of the embryonic form of the neural cell adhesion molecule in schizophrenic brains.

Schizosaccharomyces pombe mutants that are defective in glycoprotein galactosylation.

Identification of the porcine intestinal accessory factor that enables DNA sequence recognition by vitamin D receptor.

Molecular identification of porcine interleukin 10: regulation of expression in a kidney allograft model.

Serological response patterns of melanoma patients immunized with a GM2 ganglioside conjugate vaccine.

A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene.

Endogenously opsonized particles divert prostanoid action from lethal to protective in models of experimental endotoxemia.

Transferrin-antibody fusion proteins are effective in brain targeting.

Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication.

Opposite effects of transforming growth factor alpha and epidermal growth factor on mouse placental lactogen I secretion.

Lactation is disrupted by alpha-lactalbumin deficiency and can be restored by human alpha-lactalbumin gene replacement in mice.

Interleukin 1 alpha and tumor necrosis factor alpha stimulate autocrine amphiregulin expression and proliferation of human papillomavirus-immortalized and carcinoma-derived cervical epithelial cells.

Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis.

Intraspecific diversity and ecological zonation in coral-algal symbiosis.

Comprehensive allelotyping of human renal cell carcinomas using microsatellite DNA probes.

gp130 and c-Kit signalings synergize for ex vivo expansion of human primitive hemopoietic progenitor cells.

Requirement for a phospholipase C in odor response: overlap between olfaction and vision in Drosophila.

Erythropoietin-induced cellular differentiation requires prolongation of the G1 phase of the cell cycle.

Distinct coated vesicles labeled for p200 bud from trans-Golgi network membranes.

Diverse incidences of individual oligopeptides (dipeptidic to hexapeptidic) in proteins of human, bakers' yeast, and Escherichia coli origin registered in the Swiss-Prot data base.

Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis.

In vivo cytokine gene transfer by gene gun reduces tumor growth in mice.

Combinatorial diffusion assay used to identify topically active melanocyte-stimulating hormone receptor antagonists.

The neural substrates underlying word generation: a bilingual functional-imaging study.

Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity.

Induction of an outer surface protein on Borrelia burgdorferi during tick feeding.

Delivery of angiotensin II type 1 receptor antisense inhibits angiotensin action in neurons from hypertensive rat brain.

Effects of serotonergic agents on neuronal nicotinic acetylcholine receptors.

Defective G protein activation of the cAMP pathway in rat kidney during genetic hypertension.

Photochemistry and spectroscopy of a five-chlorophyll reaction center of photosystem II isolated by using a Cu affinity column.

DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I.

Structure, expression, and chromosomal localization of the type I human vasoactive intestinal peptide receptor gene.

Scrapie prions selectively modify the stress response in neuroblastoma cells.

Crystal structure of bovine angiogenin at 1.5-A resolution.

Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms.

Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis.

Primary structure of a potent endogenous dopa-containing inhibitor of phenol oxidase from Musca domestica.

Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors.

Membrane permeabilization by Listeria monocytogenes phosphatidylinositol-specific phospholipase C is independent of phospholipid hydrolysis and cooperative with listeriolysin O.

Ras membrane targeting is essential for glucose signaling but not for viability in yeast.

A multimerizing transcription factor of sea urchin embryos capable of looping DNA.

Heat shock protein synthesis and thermotolerance in Cataglyphis, an ant from the Sahara desert.

An intragenic tandem duplication of genomic DNA is responsible for the f3N mutation of Drosophila melanogaster.

Immunoregulatory activity of a T-cell receptor alpha chain demonstrated by in vitro transcription and translation.

Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus.

Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease.

Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface.

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells.

Convergent processing in honeybee vision: multiple channels for the recognition of shape.

Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain.

The primary structure of sensory rhodopsin II: a member of an additional retinal protein subgroup is coexpressed with its transducer, the halobacterial transducer of rhodopsin II.

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity.

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

Retinoic acid inhibition of ex vivo human immunodeficiency virus-associated apoptosis of peripheral blood cells.

Isolation of an amino-terminal deleted recombinant ADP-ribosylation factor 1 in an activated nucleotide-free state.

Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20.

Activation of nicotinic receptors triggers exocytosis from bovine chromaffin cells in the absence of membrane depolarization.

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration.

Origin of the foraminifera.

Cloning and sequence analysis of the rat augmenter of liver regeneration (ALR) gene: expression of biologically active recombinant ALR and demonstration of tissue distribution.

DNA sequence support for a close phylogenetic relationship between some storks and New World vultures

Functional chicken gizzard heavy meromyosin expression in and purification from baculovirus-infected cells

crnA encodes a nitrate transporter in Aspergillus nidulans