Focus AgendaRegistration Abstracts Speakers Travel Contact
Lipids and the Pathophysiology of Obesity



MAY 10, 2004


Auditorium (Meeting room level)


7:00-8:00

Continental Breakfast and Registration

8:00-8:10
Introductions and opening remarks

8:10-8:50
Plenary 1: Ron Evans
Metabolic communication between muscle and fat:
You say hello I say goodbye


Session I: Lipids and roles in obesity

8:50-9:15
Richard Bergman
Regional adiposity and insulin resistance

9:15-9:40
Luciano Rossetti
Hypothalamic sensing of nutrients plays a pivotal
role in the regulation of liver glucose homeostasis


9:40-10:05
Mitchell Lazar
Update on Resistin

10:05-10:30
Break

10:30-10:55
Jonathan Graff
Invertebrate models of fat storage

10:55-11:20
David Bernlohr
Intracellular fatty acid trafficking and the metabolic syndrome

11:20-11:40
HOT TOPIC
Daniele Piomelli
Oleylethanolamide: an endogenous PPAR-alpha ligand involved in the control of satiety and body weight

11:40-1:00
Lunch (on your own)

1:00-1:40
Plenary 2: Edward Dennis (Co-Chair)
Lipidomics and lipid signaling in the macrophage:
The Lipid Maps Initiative


Session II: Lipids and biological signaling

1:40-2:05
David Mangelsdorf (Co-Chair)
The role of nuclear receptors as lipid sensors

2:05-2:30
Neil Ruderman
AMPK, Malonyl CoA and Obesity

2:30-2:55
Robert Murphy
Qualitative and quantitative analysis of lipids by mass spectrometry

2:55-3:10

Break

3:10-3:35
Valerie Large
Regulation, expression and activity of hormone-sensitive lipase in adipose tissue of obese subjects

3:35-4:00
Barbara Kahn
AMP Kinase: Sensor of metabolic stress

4:00-4:20
HOT TOPIC
Bruce Kristal
Biomarkers for caloric intake in rats

4:30-6:30
Poster session and reception
Congressional B (ballroom level)



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MAY 11, 2004

Auditorium (Meeting room level)


7:00-8:00
Continental Breakfast and Registration

8:00-8:40
Plenary 3: Jean Schaffer (Co-Chair)
Lipotoxicity: Insights into cellular mechanisms

Session III: Pathology associated with intracellular storage and metabolism of lipids

8:40-9:05
Jerry Nadler
Role of 12- lipoxygenase generated lipids in beta cell toxicity

9:05-9:30
Christopher Glass
Roles of PPARs in macrophage biology and atherosclerosis

9:30-9:55
Daniel Kelly
Derangements in PPAR signaling leading to lipotoxic cardiomyopathy

9:55-10:15
Break

10:15-10:40
Bruce Spiegelman
OXPHOS pathway dysregulated in human diabetes is controlled by PGC-1 coactivation

10:40-11:05
Sonia Caprio
The metabolic phenotype of pre-diabetes in obese youth

11:05-11:30
Ahmed Kissebah
Positional candidate genes affecting the abdominal-obesity metabolic syndrome

11:30-11:45
HOT TOPIC
Francis Kuhajda
Fatty acid metabolism:
New strategies for obesity therapy


11:45-1:00
Lunch (on your own)

1:00-1:20
Philip Smith
Future directions in obesity research

1:20-2:00
Roger Cone
Multiple roles for melanocortin signaling in lipid metabolism

Session IV: Pathophysiology of obesity

2:00-2:25
Richard Weindruch
Metabolic shifts induced by caloric restriction in monkeys and mice

2:25-2:50

David Kelley
Skeletal muscle metabolism in the metabolic syndrome

2:50-3:15
HOT TOPIC
John Baxter
Thyroid hormone receptor modulators for treatment of obesity and dyslipidemia

3:15-3:40
Discussion and Closing Remarks




NIDDK logo
National Institute of Diabetes
& Digestive & Kidney Diseases




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