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UGID:1204598     UniGene Hs.530331     Homo sapiens (human)   PDHA1
Pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001067997.1 PREDICTED: similar to Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (PDHE1-A type I) isoform 2 R. norvegicus 99.0 398
NP_726947.1 lethal (1) G0334 CG7010-PB, isoform B D. melanogaster 74.8 314

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (1.1 pct) in cDNA library dbEST:6972, UT0091.
Note: Highly represented (1.0 pct) in cDNA library dbEST:7818, HN0035.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; lung; uncharacterized tissue; mixed; kidney; muscle; uterus; intestine; placenta; embryonic tissue; skin; liver; eye; testis; prostate; adipose tissue; heart; blood; thyroid; mammary gland; cervix; pharynx; thymus; pancreas; stomach; ovary; trachea; vascular; esophagus; ear; spleen; parathyroid; ascites; lymph; spinal cord; mouth; connective tissue; bone marrow; larynx; amniotic fluid; salivary gland; bone; adrenal gland; umbilical cord; lymph node; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp22.2-p22.1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (30)

M24848.1 Human pyruvate dehydrogenase alpha subunit mRNA, complete cds P
AK129887.1 Homo sapiens cDNA FLJ26377 fis, clone HRT06382, highly similar to Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (EC 1.2.4.1) P
NM_000284.2 Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), nuclear gene encoding mitochondrial protein, mRNA A
CR625908.1 full-length cDNA clone CS0DI043YH10 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR624456.1 full-length cDNA clone CS0DI065YN07 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR616765.1 full-length cDNA clone CS0DJ011YJ04 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR615265.1 full-length cDNA clone CS0DI076YA23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR614489.1 full-length cDNA clone CS0DI039YC12 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR614198.1 full-length cDNA clone CS0DJ009YP16 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR609764.1 full-length cDNA clone CS0DF009YJ14 of Fetal brain of Homo sapiens (human) P
CR605170.1 full-length cDNA clone CS0DI007YO13 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604641.1 full-length cDNA clone CS0DB001YG04 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
CR604489.1 full-length cDNA clone CS0DF014YL16 of Fetal brain of Homo sapiens (human) P
CR592178.1 full-length cDNA clone CS0DI042YE22 of Placenta Cot 25-normalized of Homo sapiens (human) A
CR590359.1 full-length cDNA clone CS0DL001YK20 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
AK222988.1 Homo sapiens mRNA for pyruvate dehydrogenase (lipoamide) alpha 1 variant, clone: HSI04186 P
AK222740.1 Homo sapiens mRNA for pyruvate dehydrogenase (lipoamide) alpha 1 variant, clone: DMC00706 PA
L48690.1 Homo sapiens pyruvate dehydrogenase E1-alpha subunit precursor (PDHA1) mRNA, complete cds PA
J03575.1 Human pyruvate dehydrogenase alpha subunit mRNA, complete cds P
J03503.1 Human pyruvate dehydrogenase E1-alpha subunit mRNA, cds P
L13318.1 Human pyruvate dehydrogenase E1-alpha subunit (PDHA1) mRNA, complete cds P
BC002406.1 Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 1, mRNA (cDNA clone MGC:8609 IMAGE:2961286), complete cds PA
EF576990.1 Homo sapiens PDHA1 (PDHA1) mRNA, partial cds
EF590117.1 Homo sapiens clone IMAGE:1925777 mitochondrial PDHA1 (PDHA1) mRNA, complete cds; nuclear gene for mitochondrial product
EF590116.1 Homo sapiens clone IMAGE:1571916 PDHA1 mRNA, complete sequence
AK312263.1 Homo sapiens cDNA, FLJ92558, highly similar to Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), mRNA
AK092210.1 Homo sapiens cDNA FLJ34891 fis, clone NT2NE2017562
X52709.1 Human mRNA for brain pyruvate dehydrogenase (EC 1.2.4.1) PA
X52710.1 Human mRNA for liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit P
S57358.1 pyruvate dehydrogenase alpha subunit {3'region} [human, mRNA Partial Mutant, 129 nt]

EST sequences (10 of 982) [Show all sequences]

R14441.1 Clone IMAGE:28715 brain 5' read
AA971748.1 Clone IMAGE:1583692 mixed 3' read A
AA988758.1 Clone IMAGE:1605409 kidney 3' read A
AA993771.1 Clone IMAGE:1621687 testis 3' read P
AA993961.1 Clone IMAGE:1628137 mixed 3' read
AA994799.1 Clone IMAGE:1631672 mammary gland 3' read PA
AA905785.1 Clone IMAGE:1504761 mixed 3' read A
AI002591.1 Clone IMAGE:1610479 uncharacterized tissue 3' read P
AI005175.1 Clone IMAGE:1632168 mammary gland 3' read PA
AI042603.1 Clone IMAGE:1665847 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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