Protein tyrosine phosphatase, non-receptor type 11, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (7.8 pct) in cDNA library dbEST:4450, OT0091.

Highly represented (2.7 pct) in cDNA library dbEST:5247, HT0600.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; embryonic tissue; uncharacterized tissue; uterus; mouth; ovary; esophagus; placenta; skin; mixed; cervix; bone marrow; thyroid; testis; pharynx; eye; kidney; prostate; lung; mammary gland; intestine; connective tissue; liver; lymph node; stomach; blood; spleen; thymus; pancreas; muscle; parathyroid; bladder; ascites; heart; bone; larynx; vascular; epididymis; nerve; lymph; pineal gland; ear

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Finding cDNAs

UGID:722011 UniGene Hs.506852 Homo sapiens (human) PTPN11

Order cDNA clone, Links

Protein tyrosine phosphatase, non-receptor type 11 (PTPN11)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001110117.1	PREDICTED: similar to protein tyrosine phosphatase, non-receptor type 11	M. mulatta	100.0	592

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	12
	Map position:	12q24

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

L03535.1	Homo sapiens phosphotyrosyl-protein phosphatase (SH-PTP2) mRNA, complete cds	P
BT007106.1	Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) mRNA, complete cds	P
BX537632.1	Homo sapiens mRNA; cDNA DKFZp686G13208 (from clone DKFZp686G13208)	A
CR597346.1	full-length cDNA clone CS0DC018YK13 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)
NM_002834.3	Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), mRNA	PA
BC007869.2	Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), mRNA (cDNA clone IMAGE:4303171)	A
BC008692.1	Homo sapiens protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone MGC:17206 IMAGE:3872007), complete cds	PA
L07527.1	Homo sapiens protein-tyrosine phosphatase mRNA, complete cds	P
AK289854.1	Homo sapiens cDNA FLJ75588 complete cds, highly similar to Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) (PTPN11), mRNA
AK312147.1	Homo sapiens cDNA, FLJ92431
BC025181.1	Homo sapiens protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone IMAGE:5114644), complete cds	A
EU779708.1	Homo sapiens protein tyrosine phosphatase-2 (PTPN11) mRNA, complete cds
EU779707.1	Homo sapiens protein tyrosine phosphatase-2 (PTPN11) mRNA, partial cds
EU779706.1	Homo sapiens protein tyrosine phosphatase-2 (PTPN11) mRNA, partial cds
BC030949.1	Homo sapiens protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone IMAGE:4658625), complete cds	A
S78088.1	Homo sapiens protein-tyrosine phosphatase (BPTP-3) mRNA, partial cds	P
X70766.1	H.sapiens mRNA for phosphotyrosine phosphatase	P
L08807.1	Human protein tyrosine phosphatase mRNA	P
U79291.1	Human clone 23721 mRNA sequence	A
D13540.1	Homo sapiens SH-PTP3 mRNA for protein-tyrosine phosphatase, complete cds	P

EST sequences (10 of 489) [Show all sequences]

AA962743.1	Clone IMAGE:1573380	kidney	3' read	A
AA903317.1	Clone IMAGE:1517380	uncharacterized tissue	3' read	A
AA985244.1	Clone IMAGE:1629438	brain	3' read	P
AA995560.1	Clone IMAGE:1604158	lung	3' read	P
R17740.1	Clone IMAGE:31108	brain	5' read
AI041853.1	Clone IMAGE:1660440	mixed	3' read	A
R19700.1	Clone IMAGE:34594	brain	5' read
R19952.1	Clone IMAGE:34773	brain	5' read
AI055935.1	Clone IMAGE:1659178	embryonic tissue	3' read
AI076633.1	Clone IMAGE:1676947	embryonic tissue	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria