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Finding cDNAs
UGID:687169     UniGene Hs.472010     Homo sapiens (human)   PRNP Order cDNA clone, Links
Prion protein (PRNP)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_001103676.1 prion protein preproprotein P. troglodytes 100.0 252

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (2.0 pct) in cDNA library dbEST:5100, BT0763.
Note: Highly represented (1.4 pct) in cDNA library dbEST:5239, HT0587.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; kidney; skin; testis; mixed; intestine; cervix; prostate; eye; uterus; placenta; liver; pancreas; thyroid; vascular; lung; esophagus; bone marrow; mammary gland; uncharacterized tissue; muscle; embryonic tissue; blood; connective tissue; bladder; thymus; heart; ganglia; lymph node; adipose tissue; mouth; bone; pituitary gland; ovary; stomach; trachea; nerve; adrenal gland; ear; umbilical cord; pharynx; larynx; lymph; ascites; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20p13
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

NM_183079.2 Homo sapiens prion protein (PRNP), transcript variant 2, mRNA A
NM_000311.3 Homo sapiens prion protein (PRNP), transcript variant 1, mRNA A
AY569456.1 Homo sapiens prion protein (PRNP) mRNA, complete cds P
CR542072.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0736D for gene PRNP, prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); complete cds, without stopcodon P
CR542039.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0236D for gene PRNP, prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); complete cds, incl. stopcodon P
CR613118.1 full-length cDNA clone CS0DE006YN17 of Placenta of Homo sapiens (human)
CR611378.1 full-length cDNA clone CS0DK006YM10 of HeLa cells Cot 25-normalized of Homo sapiens (human)
CR597450.1 full-length cDNA clone CS0DN002YF05 of Adult brain of Homo sapiens (human)
BT019496.1 Homo sapiens prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) mRNA, complete cds P
M13899.1 Human prion protein (PrP) mRNA, complete cds P
AY008282.1 Homo sapiens prion protein (PRNP) mRNA, complete cds P
NM_001080123.1 Homo sapiens prion protein (PRNP), transcript variant 5, mRNA A
NM_001080122.1 Homo sapiens prion protein (PRNP), transcript variant 4, mRNA A
NM_001080121.1 Homo sapiens prion protein (PRNP), transcript variant 3, mRNA A
BC012844.1 Homo sapiens prion protein, mRNA (cDNA clone MGC:8899 IMAGE:3863784), complete cds PA
BC016809.1 Homo sapiens prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia), mRNA (cDNA clone IMAGE:4078124) A
BC022532.1 Homo sapiens prion protein, mRNA (cDNA clone MGC:26679 IMAGE:4813982), complete cds PA
AK312276.1 Homo sapiens cDNA, FLJ92574, highly similar to Homo sapiens prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) (PRNP), mRNA
AB300824.1 Homo sapiens PRNP mRNA for prion, complete cds, polymorphism: PrP 129V
AB300823.1 Homo sapiens PRNP mRNA for prion, complete cds, polymorphism: PrP 129M
AK090575.1 Homo sapiens cDNA FLJ33256 fis, clone ASTRO2005557, highly similar to MAJOR PRION PROTEIN PRECURSOR P
AK293312.1 Homo sapiens cDNA FLJ52533 complete cds, highly similar to Major prion protein precursor
AK295943.1 Homo sapiens cDNA FLJ52548 complete cds, highly similar to Major prion protein precursor
AK295415.1 Homo sapiens cDNA FLJ52543 complete cds, highly similar to Major prion protein precursor
X82545.1 H.sapiens mRNA for prion protein

EST sequences (10 of 2159) [Show all sequences]

AA954963.1 Clone IMAGE:1577753 mixed 3' read A
AA999757.1 Clone IMAGE:1612930 uncharacterized tissue 3' read A
AA904922.1 Clone IMAGE:1504511 mixed 3' read A
AI023011.1 Clone IMAGE:1650952 parathyroid 3' read A
AI052690.1 Clone IMAGE:1676435 embryonic tissue 3' read A
AA946805.1 Clone IMAGE:1589077 kidney 3' read A
AI074314.1 Clone IMAGE:1679346 skin 3' read A
AI081456.1 Clone IMAGE:1680406 skin 3' read A
AI082528.1 Clone IMAGE:1660250 embryonic tissue 3' read
AI090185.1 Clone IMAGE:1696646 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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