Parkinson disease (autosomal recessive, early onset) 7, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.3 pct) in cDNA library dbEST:6790, ADA.

Highly represented (1.2 pct) in cDNA library dbEST:10296, S2SNU668s1.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; prostate; lung; uterus; ascites; eye; embryonic tissue; liver; mixed; skin; blood; placenta; bone; pancreas; uncharacterized tissue; muscle; heart; intestine; connective tissue; larynx; spleen; adipose tissue; lymph; mammary gland; kidney; lymph node; thymus; nerve; testis; bone marrow; pharynx; adrenal gland; ovary; mouth; ear; pituitary gland; stomach; cervix; vascular; parathyroid; tonsil; umbilical cord; thyroid; salivary gland; bladder; spinal cord

NCBI

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Finding cDNAs

UGID:223998 UniGene Hs.419640 Homo sapiens (human) PARK7

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Parkinson disease (autosomal recessive, early onset) 7 (PARK7)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001116849.1	Parkinson disease protein 7	H. sapiens	100.0	188

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	1
	Map position:	1p36.23

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AK130886.1	Homo sapiens cDNA FLJ27376 fis, clone UBA06221, highly similar to Homo sapiens RNA-binding protein regulatory subunit	P
NM_007262.4	Homo sapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1, mRNA	A
CR623919.1	full-length cDNA clone CS0DC023YN06 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
CR619796.1	full-length cDNA clone CS0DC004YH15 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
CR618546.1	full-length cDNA clone CS0DK012YC18 of HeLa cells Cot 25-normalized of Homo sapiens (human)	P
CR616157.1	full-length cDNA clone CS0DJ001YN11 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human)	P
CR591123.1	full-length cDNA clone CS0DJ011YE07 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human)	P
BC008188.2	Homo sapiens Parkinson disease (autosomal recessive, early onset) 7, mRNA (cDNA clone MGC:5243 IMAGE:2901102), complete cds	PA
AB073864.1	Homo sapiens mRNA for DJ-1, complete cds	P
AK312000.1	Homo sapiens cDNA, FLJ92274, highly similar to Homo sapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7), mRNA
NM_001123377.1	Homo sapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 2, mRNA	A
D61380.2	Homo sapiens mRNA for DJ-1 protein, complete cds	PA
AF021819.1	Homo sapiens RNA-binding protein regulatory subunit mRNA, complete cds	PA

EST sequences (10 of 1171) [Show all sequences]

AA969322.1	Clone IMAGE:1580490	mixed	3' read	A
AA969401.1	Clone IMAGE:1580538	mixed	3' read	PA
AA927139.1	Clone IMAGE:1541577	mixed	3' read
AI023091.1	Clone IMAGE:1650522	parathyroid	3' read	PA
AA908891.1	Clone IMAGE:1550735	uncharacterized tissue	3' read	PA
AI031586.1	Clone IMAGE:1646055	parathyroid	3' read	A
AI034225.1	Clone IMAGE:1646360	parathyroid	3' read	PA
AI034314.1	Clone IMAGE:1647680	parathyroid	3' read	PA
AI034421.1	Clone IMAGE:1647169	parathyroid	3' read	P
AI042422.1	Clone IMAGE:1665028	skin	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria