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UGID:164319     UniGene Hs.211463     Homo sapiens (human)   DNM2
Dynamin 2 (DNM2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001103119.1 PREDICTED: dynamin 2 isoform 4 M. mulatta 100.0 869
NP_001005360.1 dynamin 2 isoform 1 H. sapiens 100.0 869
XP_512382.2 PREDICTED: dynamin 2 P. troglodytes 99.8 825
NP_001034609.1 dynamin 2 M. musculus 99.7 868
NP_037331.1 dynamin 2 R. norvegicus 99.5 869
NP_001093354.1 hypothetical protein LOC100101298 X. laevis 94.7 866
NP_998407.1 dynamin 2 D. rerio 90.2 855
NP_001036278.1 shibire CG18102-PH, isoform H D. melanogaster 77.5 829
NP_001024332.1 DYNamin related family member (dyn-1) C. elegans 73.7 833
XP_323440.1 hypothetical protein N. crassa 58.9 576
NP_565363.2 dynamin-like protein 2b (ADL2b) A. thaliana 52.9 739
NP_013100.1 Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis; Dnm1p S. cerevisiae 52.1 753
XP_001700931.1 dynamin-related GTPase C. reinhardtii 49.1 515

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (21.9 pct) in cDNA library dbEST:6942, TN0115.
Note: Highly represented (3.8 pct) in cDNA library dbEST:6661, HT0923.
Note: Highly represented (1.3 pct) in cDNA library dbEST:7023, BN0410.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; testis; intestine; uncharacterized tissue; placenta; thymus; spleen; pharynx; vascular; trachea; blood; embryonic tissue; connective tissue; lung; muscle; kidney; ovary; mammary gland; cervix; uterus; lymph node; adrenal gland; pancreas; skin; mouth; larynx; liver; mixed; eye; prostate; pituitary gland; lymph; nerve; stomach; thyroid; ascites; salivary gland; bladder; bone; bone marrow; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.2
UniSTS entry: Chr 19 STS-L36983
UniSTS entry: Chr Y (n/a)
UniSTS entry: Chr Y D16S325
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BC054501.1 Homo sapiens dynamin 2, mRNA (cDNA clone MGC:57679 IMAGE:6473791), complete cds PA
AK127033.1 Homo sapiens cDNA FLJ45089 fis, clone BRAWH3029385, highly similar to Dynamin 2 (EC 3.6.1.50) P
AK126192.1 Homo sapiens cDNA FLJ44204 fis, clone THYMU3001234, highly similar to Dynamin 2 (EC 3.6.1.50) P
AK124881.1 Homo sapiens cDNA FLJ42891 fis, clone BRHIP3008405, highly similar to Dynamin 2 (EC 3.6.1.50) P
NM_004945.2 Homo sapiens dynamin 2 (DNM2), transcript variant 3, mRNA P
CR626015.1 full-length cDNA clone CS0DL012YG03 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
NM_001005362.1 Homo sapiens dynamin 2 (DNM2), transcript variant 4, mRNA P
NM_001005361.1 Homo sapiens dynamin 2 (DNM2), transcript variant 2, mRNA P
NM_001005360.1 Homo sapiens dynamin 2 (DNM2), transcript variant 1, mRNA P
AY927542.1 Homo sapiens mRNA sequence P
AB209213.1 Homo sapiens mRNA for dynamin 2 isoform 4 variant protein P
AK023207.1 Homo sapiens cDNA FLJ13145 fis, clone NT2RP3003282, highly similar to Homo sapiens dynamin (DNM) mRNA P
L36983.1 Homo sapiens dynamin (DNM) mRNA, complete cds P
AK289831.1 Homo sapiens cDNA FLJ78533 complete cds, highly similar to Homo sapiens dynamin 2 (DNM2), transcript variant 4, mRNA P
AK312260.1 Homo sapiens cDNA, FLJ92555 P
AK097989.1 Homo sapiens cDNA FLJ40670 fis, clone THYMU2020959, highly similar to Dynamin-2 (EC 3.6.5.5) P
AK097875.1 Homo sapiens cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2 P
AK295929.1 Homo sapiens cDNA FLJ56447 complete cds, highly similar to Dynamin-2 (EC 3.6.5.5) P
BC039596.1 Homo sapiens dynamin 2, mRNA (cDNA clone MGC:48834 IMAGE:5722134), complete cds PA

EST sequences (10 of 611) [Show all sequences]

AI049691.1 Clone IMAGE:1700470 kidney 3' read
AI057264.1 Clone IMAGE:1669666 brain 3' read A
BX093903.1 Clone IMAGp998F145381_;_IMAGE:2178061 uterus A
CB130369.1 Clone L12JSHC0-7-B10 liver 5' read P
AA887978.1 Clone IMAGE:1160125 intestine 3' read A
AI245500.1 Clone IMAGE:1869962 kidney 3' read A
AI285965.1 Clone IMAGE:1854978 mixed 3' read
AI310442.1 Clone IMAGE:1913626 intestine 3' read A
AI369074.1 Clone IMAGE:1992550 uterus 3' read A
AI499081.1 Clone IMAGE:2178061 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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