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UGID:155663     UniGene Hs.159494     Homo sapiens (human)   BTK Order cDNA clone, Links
Bruton agammaglobulinemia tyrosine kinase (BTK)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_549139.2 PREDICTED: similar to Bruton agammaglobulinemia tyrosine kinase isoform 1 C. lupus familiaris 99.2 658
NP_001097120.1 Btk family kinase at 29A CG8049-PF, isoform F D. melanogaster 59.3 450
NP_001712.1 BMX non-receptor tyrosine kinase H. sapiens 57.9 668

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: blood; thyroid; tonsil; mammary gland; liver; heart; spleen; mixed; bone marrow; lymph; brain; uncharacterized tissue; lymph node; skin; lung; stomach; intestine; connective tissue; pharynx; adrenal gland; esophagus; thymus; trachea; uterus; testis; pancreas; placenta; prostate; muscle; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq21.33-q22
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (37)

NM_000061.1 Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), mRNA PA
AF153756.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153757.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153758.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153759.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153760.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153761.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153762.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AF153763.1 Homo sapiens Bruton's tyrosine kinase mRNA, partial cds P
AF153764.1 Homo sapiens Bruton's tyrosine kinase mRNA, partial cds P
AF153364.1 Homo sapiens Bruton's tyrosine kinase mRNA, complete cds P
AJ888381.1 Homo sapiens partial mRNA for tyrosine-protein kinase BTK isoform (lacking exon 14) (BTK gene), tissue type BCR-ABL1+ pre-B lymphoblastic leukemia P
AJ888380.1 Homo sapiens partial mRNA for tyrosine-protein kinase BTK isoform (lacking exon 15 to 18) (BTK gene), tissue type BCR-ABL1+ pre-B lymphoblastic leukemia P
AJ888379.1 Homo sapiens partial mRNA for tyrosine-protein kinase BTK isoform (lacking exon 13 to 17) (BTK gene), tissue type BCR-ABL1+ pre-B lymphoblastic leukemia
AJ888378.1 Homo sapiens partial mRNA for tyrosine-protein kinase BTK isoform 52 (BTK gene), tissue type BCR-ABL1+ pre-B lymphoblastic leukemia P
AJ888377.1 Homo sapiens partial mRNA for tyrosine-protein kinase BTK isoform 51 (BTK gene), tissue type BCR-ABL1+ pre-B lymphoblastic leukemia P
AJ888376.1 Homo sapiens partial mRNA for tyrosine-protein kinase BTK isoform 65 (BTK gene), tissue type BCR-ABL1+ pre-B lymphoblastic leukemia P
AM051286.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 12 (BTK kinase deficient isoform 12 gene), cell type E2A-PBX1+ leukemia cells
AM051285.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 11 (BTK kinase deficient isoform 11 gene), cell type E2A-PBX1+ leukemia cells P
AM051284.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 10 (BTK kinase deficient isoform 10 gene), cell type TEL-AML1+ leukemia cells P
AM051283.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 9 (BTK kinase deficient isoform 9 gene), cell type TEL-AML1+ leukemia cells
AM051282.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 8 (BTK kinase deficient isoform 8 gene), cell type TEL-AML1+ leukemia cells P
AM051281.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 7 (BTK kinase deficient isoform 7 gene), cell type TEL-AML1+ leukemia cells
AM051280.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 6 (BTK kinase deficient isoform 6 gene), cell type BCR-ABL1+ leukemia cells P
AM051279.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 5 (BTK kinase deficient isoform 5 gene), cell type BCR-ABL1+ leukemia cells P
AM051278.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 4 (BTK kinase deficient isoform 4 gene), cell type BCR-ABL1+ leukemia cells P
AM051277.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 3 (BTK kinase deficient isoform 3 gene), cell type MLL-AF4+ leukemia cells P
AM051276.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 2 (BTK kinase deficient isoform 2 gene), cell type MLL-AF4+ leukemia cells P
AM051275.1 Homo sapiens partial mRNA for dominant-negative kinase-deficient Brutons tyrosine kinase isoform 1 (BTK kinase deficient isoform 1 gene), cell type BCR-ABL1+ and MLL-AF4+ leukemia cells P
BC109080.1 Homo sapiens Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone MGC:126262 IMAGE:40034289), complete cds P
BC109079.1 Homo sapiens Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone MGC:126261 IMAGE:40034287), complete cds P
AK225577.1 Homo sapiens mRNA for Bruton agammaglobulinemia tyrosine kinase variant, clone: LNG09949 A
AK057105.1 Homo sapiens cDNA FLJ32543 fis, clone SMINT2000538, highly similar to Tyrosine-protein kinase BTK (EC 2.7.10.2) P
AK314382.1 Homo sapiens cDNA, FLJ95155, highly similar to Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), mRNA
AK309851.1 Homo sapiens cDNA, FLJ99892
AF153755.1 Homo sapiens Bruton's tyrosine kinase mRNA, partial cds P
X58957.1 H.sapiens atk mRNA for agammaglobulinaemia tyrosine kinase PA

EST sequences (10 of 146) [Show all sequences]

AA911703.1 Clone IMAGE:1521055 lung 3' read A
BX097544.1 Clone IMAGp998B09659_;_IMAGE:295208 mixed
AI184357.1 Clone IMAGE:1714351 placenta 3' read A
AA907149.1 Clone IMAGE:1370789 lymph node 3' read
AI361486.1 Clone IMAGE:2015215 brain 3' read A
AI362055.1 Clone IMAGE:2014424 brain 3' read A
AI571957.1 Clone IMAGE:2223789 pancreas 3' read A
AI768960.1 Clone IMAGE:2364069 mixed 3' read A
BX325261.2 Clone CS0DL002YE22 uncharacterized tissue 3' read
BX325262.2 Clone CS0DL002YE22 uncharacterized tissue 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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