National Cancer Institute - IMAT

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Abersold, Ruedi

Isotope Coded Affinity Tags for Quantitative Proteomics

[ Expand Publications ]

  1. Quantitative Proteome Analysis: Methods and Applications; R. Aebersold, B. Rist, S. Gygi, Annals of the New York Academy of Science, Vol 919, 2000, pp 33-47.
  2. Mass Spectrometry and Proteomics; S. Gygi, R. Aebersold, Current Opinions in Chemical Biology, Vol 4, 2000, pp 489-94.
  3. Using Mass Spectrometry for Quantitative Proteomics; S. Gygi, R. Aebersold, Proteomics: A Trends Guide, 2000, pp 31-6.
  4. Evaluation of Two-Dimensional Gel Electrophoresis-Based Proteome Analysis Technology; S. Gygi, G. Corthals, Y. Zhang, Y. Rochon, R. Aebersold, Proceedings of the National Academy of Science USA, Vol 97, No 17, 2000, pp 9390-5.
  5. Measuring Gene Expression by Quantitative Proteome Analysis; S. Gygi, B. Rist, R. Aebersold, Current Opinions in Biotechnology, Vol 11, 2000, pp 396-401.
  6. A Systematic Approach to the Analysis of Protein Phosphorylation, Nature Biotechnology, Vol 19, 2001, pp 375-8.
  7. Integrated Genomic and Proteomic Analysis of a Systematically Perturbed Metabolic Network; T. Ideker, V. Thorsson, J. Ranish, R. Christmas, J. Buhler, R. Bumgarner, R. Aebersold, L. Hood, Science, Vol 292, 2001, pp 929-34.
  8. Quantitative Proteomic Analysis Using a MALDI Quadrupole Time-of-Flight Mass Spectrometer; T. Griffin, A. Loboda, S. Gygi, B. Rist, K. Standing, R. Aebersold, Analytical Chemistry, Vol 73, No 5, 2001, pp 978-86.
  9. Advances in Proteome Analysis by Mass Spectrometry; T. Griffin, R. Aebersold, Journal of Biological Chemistry, 2001 (in press).
Bensimon, Aaron

Detection of Genomic Alterations by Molecular Combing

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  1. Replication Fork Density Increases During DNA Synthesis in X.laevis Egg Extracts; J. Herrick, P. Stanislawski, O. Hyrien, A. Bensimon; J. Mol. Biol. 300, 2000, pp 1133-1142.
  2. Targeting the Molecular Mechanism of DNA Replication for the Development of New Drugs: A Single DNA Molecule Approach; C. Conti, S. Caburet, A. Bensimon, Drug Discovery Today, 2001 (in press).
  3. Molecular Combing: Gaining Insights in the Role of DNA Replication in Genomic Instability; S. Caburet, C. Conti, A. Bensimon, Trends in Biotechnology, 2001 (in press).
Bitter, Grant A.

DNA Mismatch Repair Functional Genetic Tests

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  1. Functional Genetic Tests of DNA Mismatch Repair Protein Activity in Saccharomyces Cerevisiae; P.J. Polaczek, A.P. Putzke, K.L. Leong and G.A. Bitter, Gene 213, 1998, pp 159-167.
  2. Functional Analysis of Human MLH1 and MSH2 Missense Variants and Hybrid Human-yeast MLH1 Proteins in Saccharomyces Cerevisiae; A.R. Ellison, J. Lofing, G.A. Bitter, Human Molecular Genetics, 10, 18, 2001, pp 1889-1900.
Bitter, Grant A.

Functional Analysis of Human MLH1 and MSH2 Missense Variants and Hybrid

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  1. Functional Analysis of Human MLH1 and MSH2 Missense Variants and Hybrid Human-yeast MLH1 Proteins in Saccharomyces Cerevisiae; A.R. Ellison, J. Lofing, and G.A. Bitter, Human Molecular Genetics, Vol 10, No 18, 2001, pg 1889-1900.
Chalmers, Jeffrey J.

Rapid Rare Cancer Cell Isolation for Molecular Diagnosis

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  1. Measurement of CD2 Expression Levels of IFN- Treated Fibrosarcomas Using Cell Tracking Velocimetry; K. McCloskey, J. Chalmers, M. Zborowski, Cytometry (in press).
  2. Continuous Cell Separation Using Novel Magnetic Quadrupole Flow Sorter; M. Zborowski, L. Sun, L. Moore, P. Williams, J. Chalmers, J. of Magnetism and Magnetic Materials, 194, 1999, pp 224-230.
  3. An Instrument to Determine the Magnetophoretic Mobility of Paramagnetic Particles and Labeled, Biological Cells; J. Chalmers, Y. Zhao, M. Nakamura, K. Melnik, L. Lasky, L. Moore, M. Zborowski, J. of Magnetism and Magnetic Materials, 194, 1999, pp 231-241.
  4. Evaluation of Eluants from Batch Separations of CD34(+) Cells from Human Cord Blood using a Commercial, Immunomagnetic Cell Separation System; K. Melnik, M. Nakamura, K. Comella, M. Zborowski, J.J. Chalmers, Biotechnol Progress, 17, 5, 2001, pp 907-916.
  5. Measurement of CD2 Expression Levels of IFN-Treated Fibrosarcomas Using Cell Tracking Velocimetry; K. McCloskey, Measurement of CD2 Expression Levels of IFN-Treated Fibrosarcomas Using Cell Tracking Velocimetry; K. McCloskey, J.J. Chalmers, M. Zborowski, Cytometry, 44, 2, 2001, pp 137-47.
  6. Flow Rate for the Quadrupole Magentic Cell Sorter; P.S. Williams, M. Zborowski, J.J. Chalmers, Analytical Chemistry, 71, 1999, pp 3799-3807.
  7. Progenitor Cell Isolation with a High-Capacity Quadrupole Magnetic Flow Sorter; L. Moore, A. Rodrigues, P. Williams, K. McCloskey, B. Bolwell, M. Nakamura, J. Chalmers, M. Zborowski, Magn. Magn. Mater, 225, 1-2, 2001, pp 277-284.
  8. Theoretical and Experimental Analysis of the Accuracy of Cell Tracking Velocimetry; M. Nakamura, L. Lasky, M. Zborowski, J. Chalmers, Experiments in Fluids, 30, 2001, pp 371-380.
  9. Study of Magnetic Particles Pulsed-Injected into an Annular SPLITT-Like Channel Inside a Quadrupole Magnetic Field; M. Hoyos, L. Moore, K. McCloskey, S. Margel, M. Zuberi, J. Chalmers, M. Zborowski, J. Chromatogr. A, 903, 1-2, 2000, pp 99-116.
  10. The Use of Magnetite-Doped Polymeric Microspheres in Calibrating Cell Tracking Velocimetry; L. Moore, L. Sun, M. Zborowski, M. Nakamura, J. Chalmers, K. McCloskey, S. Gura, I. Burdygin, S. Margel, J. Biochemical and Biophysical Methods, 44, 2000, pp 115-130.
  11. Magnetophoretic Mobilities Correlate to Antibody Binding Capacity; K. McCloskey, M. Zborowski, J. Chalmers, Cytometry, 40, 2000, pp 307-315. Erata, Cytometry, 41, 2, p 150.
  12. Quantification of Cellular Properties from External Fields and Resulting Induced Velocity: Cellular Hydrodynamic Diameter; J. Chalmers, S. Haam, Y. Zhou, K. McCloskey, L. Moore, M. Zborowski, P. Williams, Biotechnology and Bioengineering, 64, 1999, pp 509-518.
  13. Quantification of Cellular Properties from External Fields and Resulting Induced Velocity: Magnetic Susceptibility; J. Chalmers, S. Haam, Y. Zhou, K. McCloskey, L. Moore, M. Zborowski, P. Williams, Biotechnology and Bioengineering, 64, 1999, pp 519-526.
  14. Rapid Cell Isolation by Magnetic Flow Sorting for Applications in Tissue Engineering; M. Zborowski, L. Sun, L. Moore, J. Chalmers, ASIO Journal, 45, 1999, pp 127-130.
Chance, Mark R.

Dynamics of Macromolecular Interactions

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  1. Determination of Macromolecular Folding and Structure by Synchrotron X-Ray Radiolysis Techniques; S.D. Maleknia, C.Y. Ralston, M.D. Brenowitz, K.M. Downard, M.R. Chance, Vol. 289, 2001, pp 103-115.
Churchill, Gary

Experimental Design & Analysis for Expression Microarray

[ Expand Publications ]

  1. Analysis of Variance for Gene Expression Microarray Data; M.K. Kerr, M. Martin, G.A. Churchill, J Computational Biology, 7, 2000, pp 819-837.
  2. Experimental Design for Gene Expression Microarrays; M.K. Kerr, G.A. Churchill, Biostatistics, 2001 (in press).
  3. Statistical Design and the Analysis of Gene Expression Microarray Data; M.K. Kerr, G.A. Churchill, Genetical Research, 77, 2001, pp 123-128.
Condeelis, John

Novel Imaging Methods for Gene Discovery in Cancer

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  1. Lamellipodia in Invasion; J. Condeelis, J. Wyckoff, M. Bailly, R. Pestell, D. Lawrence, J. Backer, J. Segall, Seminar in Cancer Biology, 2001 (in press).
  2. EGF-Stimulated Lamellipod Extension in Adenocarcinoma Cells; C. Rotsch, K. Jacobson, J. Condeelis, M. Radmacher, Ultramicroscopy, 2001 (in press).
  3. Imaging of Cancer Invasion and Metastasis Using Green Fluorescent Protein; J. Condeelis, J. Wyckoff, J. Segall, European J. Cancer, 36, 2000, pp 1671-1680.
  4. The Collection of the Motile Population of Cells From a Living Tumor; J. Wyckoff, J. Segall, J. Condeelis, Cancer Research, 60, 2000, pp 5401-5404.
  5. A Critical Step in Metastasis: in vivo Analysis of Intravasation at the Primary Tumor; J. Wyckoff, J. Jones, J. Condeelis, J. Segal, Cancer Research, 60, 2000, pp 2504-2511.
Dabora, Sandra Lynn

Mutant Analysis of TSC1 & TSC2 in TSC Related Disorders

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  1. Mutational Analysis in a Cohort of 224 Tuberous Sclerosis Patients Indicates Increased Severity of TSC2 Compared with TSC1 Disease in Multiple Organs; S. Dabora, S. Jozwiak, D. Franz, P. Roberts, A. Nieto, J. Chung, Y. Choy, M. Reeve, E. Thiele, J. Egelhoff, J. Kasprzyk-Obara, D. Domanska-Pakiela, D. Kwiatkowski, American Journal of Human Genetics, Vol 68, 2001, pp 64-80.
Dovichi, Norman J.

Single Cell Proteome Project - Cancer Prognosis

[ Expand Publications ]

  1. One-dimensional Protein Analysis of an HT29 Human Colon Adenocarcinoma Cell; Z. Zhang, S. Krylov, E.A. Arriaga, R. Polakowski, N.J. Dovichi, Analytical Chemistry, Vol 72, 2000, pp 318-322.
  2. Instrumentation for Chemical Cytometry; S.N. Krylov, D.A. Starke, E.A. Arriaga, Z. Zhang, N.W.C. Chan, M.M. Palcic, N.J. Dovichi, Analytical Chemistry, Vol 72, 2000, pp 872-877.
  3. Separation of Proteins by Sodium Dodecyl Sulfate-capillary Electrophoresis in Hydroxypropylcellulose Sieving Matrix with Laser-induced Fluorescence Detection; S. Hu, Z. Zhang, L.M. Cook, E. Carpenter, N.J. Dovichi, Journal of Chromatography, Vol 895, 2000, pp 291-296.
  4. Capillary Electrophoresis for the Analysis of Biopolymers; S.N. Krylov, N.J. Dovichi, Analytical Chemistry, Vol 72, 2000, pp 111R-128R.
  5. Metabolic Cytometry: Monitoring Oligosaccharide Biosynthesis in Single Cells by Capillary Electrophoresis; S.N. Krylov, E.A. Arriaga, N.W.C. Chan, N.J. Dovichi, M.M. Palcic, Analytical Biochemistry, Vol 283, 2000, pp 133-135.
  6. Protein Analysis of an Individual Caenorhabditis Elegans Single-cell Embryo by Capillary Electrophoresis; S. Hu, R. Lee, Z. Zhang, S.N. Krylov, N.J. Dovichi, Journal of Chromatography, Vol 752, 2001, pp 307-310.
  7. Characterization of the Interaction Between Phospholipids and Proteins by Capillary Electrophoresis with Laser Induced Fluorescence Detection; S. Hu, L. Zhang, N.J. Dovichi, Journal of Chromatography, in press.
  8. Proteome Analysis by Capillary Electrophoresis; S. Hu, D. Michels, Z. Zhang, S.N. Krylov, N.J. Dovichi, Biotechnology, Vol. 5b Genomics, Edited by C.W. Sensen, VCH Publishers, in press.
Garner, Harold R.

Software and Instrumentation to Identify Cancer Genes

[ Expand Publications ]

  1. Digital Optical Chemistry, a Chapter in Advanced Microfabricated Sensors; K. J. Luebke, R. P. Balog, D. Mittelman, H.R. Garner, American Chemical Society Publications, 2000.
  2. A Chapter in Instrumentation for the Genome Project, Annual Reviews of Biomedical Engineering; G. Miller J. Jacklevic, H.R. Garner, Joe Jacklevic, editor, 1999.
Goldrick, Marianna M.

Detection and Quantitation of Fusion Mrnas in Leukemia

[ Expand Publications ]

  1. NIRCA: A Rapid Robust Method for Screening for Unknown Point Mutations; M. Goldrick, G. Kimball, Q. Liu, L. Martin, S. Sommer, J. Tseng, BioTechniques, Vol 21, No 2, 1996, pp 106-112.
  2. Cleavage of RNA-RNA Hybrids at Mutation Sites Using the Nonisotopic RNase Cleavage Assay (NIRCA), Current Protocols in Human Genetics, Supplement 14, Unit 7.2, 1997.
  3. RNase Cleavage-Based Methods for Mutation/SNP Detection, Past and Present; Goldrick, M. (submitted and accepted for publication in Human Mutation, 2001).
Golovlev, Valerie

Magnetic Disk Array DNA Analyzer

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  1. DNA and Protein Detection System Based On Microwave Treatment for Enhancing Detection Sensitivity; V. Golovlev. Patent Application, USPTO, February 2001.
  2. DNA Micro-Arrays on a Surface of Magnetic Media; V.V. Golovlev, C.H. Chen, S. Dai, and K. Matteson, BioTechniques (in press).
  3. Micro-Arrays in Alternative Format: Reducing Cost and Boosting Performance; News Release, www.scien-tec.com.
Huang, Tim H.

High Throughput Methylation Analysis in Cancer

[ Expand Publications ]

  1. Methylation Profiling of CpG Islands in Human Breast Cancer Cells; TH-M. Huang, M.R. Perry, D.E. Laux, Hum Mol Genet, Vol 8, 1999, pp 459-470.
  2. CpG Island Arrays: An Application Toward Deciphering Epigenetic Signatures of Breast Cancer; P.S. Yan, M.R. Perry, D.E. Laux, A.S. Asare, C.W. Caldwell, T.H-M. Huang, Clin Cancer Res, No 6, 2000, pp 1432-1438.
Jay, Daniel G.

High Throughput Cali for Target Validation in Metastasis

[ Expand Publications ]

  1. Application of Chromophore-Assisted Laser Inactivation (CALI) to Elucidate Cellular Mechanisms of Cancer; D.G. Jay and T. Sakurai, Biochim Biophys Acta, 87452, 1999, M39-M48.
  2. The TSC1 Tumor Suppressor Hamartin Regulates Cell Adhesion Through ERM Proteins and the GTPase Rho; R.F. Lamb, C. Roy, T.J. RDiefenbach, H.V. Vinters, M.W. Johnson, D.G. Jay, A. Hall, Nature Cell Biology, 2, 2000, 281-287.
  3. Chromophore-Assisted Laser Inactivation (CALI) to Validate Drug Targets and Pharmacogenomic Markers; L.L. Ilag, J.H. Ng, D.G. Jay, Drug Devel. Res., 49, 2000, 65-73.
  4. The Short Antennae Gene of Tribolium is Required for Limb Development and Encodes the Ortholog of the Drosophila Distal-less Protein; A. Beermann, D.G. Jay, R. Beeman, M. Hulskamp, D. Tautz, G. Jurgens, Development (in press).
Lam, Kit

Peptide Microarray for Cancer Cell Surface Receptors

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  1. Peptide and Small Molecule Microarray for High Throughput Cell Adhesion and Funcitonal Assays; J.R. Falsey, M. Renil, S. Park, S. Li, K.S. Lam, Bioconjugate Chemistry, Vol 12, 2001, pp 346-353.
Majumdar, Arun

Optomechanical Chips for Molecular Profiling of Cancer

[ Expand Publications ]

  1. Origin of Nanomechanical Cantilever Motion Generated from Biomolecular Interactions; G. Wu, H. Ji, K. Hansen, T. Thundat, R. Datar, R. Cote, M. Hagan, A. K. Chakraborty, A. Majumdar, Proc. National Acad. Sci., Vol. 98, No. 4, 2001, pp 1560-1564.
  2. Cantilever-based Optical Deflection Assay for Discrimination of DNA Single Nucleotide Mismatches; K. Hansen, H.-F. Ji, G. Wu, R. Datar, R. Cote, A. Majumdar, T. Thundat, Analytical Chemistry, Vol. 73, No. 7, 2001, pp. 1567-1571.
Mcclelland, Michael

Reduced Complexity CDNA Probes

[ Expand Publications ]

  1. Overexpression of Lerk-5/Eplg5 mRNA: A Novel Marker for Increased Tumorgenicity and Metastatic Potential in Human Malignant Melanomas; T. Vogt, W. Stolz, B. Jung, J. Welsh, R.S. Kerbel, M. Landthaler, M. McClelland, Clin. Cancer Res., 4, 1998, pp 791-797.
  2. Identification of Differentially Expresses Genes using RNA Fingerprinting by Arbitrarily Primed PCR; F. Mathieu-Daude, T. Trenkle, J. Welsh, J. Jung, T. Vogt, M. McClelland, Meth. Enzymol., 303, 1999, pp 309-324.
  3. Expression Genetics II: High Throughput Methods; M. McClelland, A.B. Pardee, Eaton Press, 1999.
  4. Analysis of Gene Expression Patterns in Rheumatoid Synovial Fibroblasts Using RAP-PCR for Differential Display; U. Muller-Ladner, M. Judex, H.P. Justen, D. Wessinghage, J. Welsh, M. McClelland, S. Gay, J. Scholmerich, F. Kullmann, Med Klin., 94, 1999, pp 228-232.
  5. Expression Genetics I: Differential Display; A.B. Pardee, M. McClelland, Eaton Press, 1999.
  6. Reduced Complexity Probes for DNA Arrays; T. Trenkle, F. Mathieu-Daude, J. Welsh, M. McClelland, Meth. Enzymol, 303, 1999, pp 380-392.
  7. Differential Display Probes for cDNA Arrays; T. Trenkle, J. Welsh, M. McClelland, BioTechniques, 27, 1999, pp 554-564.
  8. Deficiency of a Novel Retinoblastoma Binding Protein 2-homolog is a Consistent Feature of Sporadic Human Melanoma Skin Cancer; T. Vogt, M. Kroiss, M. McClelland, C. Gruss, B. Becker, A.K. Bosserhoff, G. Rumpler, T. Bogenrieder, M. Landthaler, W. Stolz, Lab. Invest., 79, 1999, pp 1615-1627.
  9. Web-based Visualization Tools for Bacterial Genome Alignments; L. Florea, C. Riemer, S. Schwartz, Z. Zhang, N. Stojanovic, W. Miller, M. McClelland, Nucleic Acids Res., 28, 2000, pp 3486-3496.
  10. The Role of Blood Group Antigens in Malignant Progression, Apoptosis Resistance and Metastatic Behavior; G.V. Glinsky, A.B. Ivanova, J. Welsh, M. McClelland, Transfus Med Rev., 4, 2000, pp 326-350.
  11. Arbitrarily Primed PCR Probes for cDNA Arrays; S. Ringquist, T. Trenkle, J. Welsh, M. McClelland, Methods in Molecular Medicine, D. Stirling (Ed), Humana Press, 2000.
  12. Arbitrarily Primed PCR Methods for Studying Bacterial Diseases; D. Ralph & M. McClelland, Molecular Bacteriology: Protocols and Clinical Applications. (Eds), N. Wooford & A.B. Johnson, Humana Press, Totowa, NJ.
  13. Major Transcript Variants of VAV3, A New Member of the VAV Family of Guanine Nucleotide Exchange Factors; T. Trenkle, M. McClelland, K. Adlkofer, J. Welsh, Gene, 245, 2000, pp 139-149.
  14. VAV3 Mediates Receptor Protein Tyrosine Kinase Signaling, Regulates GTPase Activity, Modulates Cell Morphology and Induces Cell Transformation; L. Zeng, P. Sachdev, L. Yan, J.L. Chan, T. Trenkle, M. McClelland, J. Welsh, L.H. Wang, Mol Cell Biol., 24, 2000, pp 9212-9224.
  15. Neural Membrane Protein 35 (NMP35): A Novel Member of a Gene Family, Which is Highly Expressed in the Adult Nervous System; B. Schweitzer, V. Taylor, A.A. Welcher, M. McClelland, U. Suter, Mol. Cell Neurosci., 11, 1998, pp 260-273.
  16. GeneUp: A Program to Select Short PCR Primer Pairs that Occur in Multiple Members of Sequence Lists; G. Pesole, S. Liuni, G. Grillo, P. Belichard, T. Trenkle, J. Welsh, M. McClelland, Biotechniques, 25, 1998, pp 112-117.
  17. Estrogen-Responsive RING Finger mRNA Induction in Gastrointestinal Carcinoma Cells Following Bile Acid Treatment; B. Jung, T. Vogt, F. Mathieu-Daude, J. Welsh, M. McClelland, T. Trenkle, C. Weitzel, F. Kullmann, Carcinogenesis, 19, 1998, pp 1901-1906.
  18. Non-stoichiometric Reduced Complexity Probes for cDNA Arrays; T. Trenkle, J. Welsh, F. Mathieu-Daude, B. Jung, M. McClelland, Nucleic Acids Res., 26, 1998, pp 3883-3891.
  19. PCR5: Differential Display: A Practical Approach; B. Jung, T. Trenkle, M. McClelland, F. Mathieu-Daude, J. Welsh; R. Leslie & H. Robertson (Eds), Oxford University Press, 1999.
  20. Kinesin-like Protein CENP-E is Upregulated in Rheumatoid Synovial Fibroblasts; F. Kullman, M. Judex, W. Ballhorn, H.P. Justen, D. Wessinghage, J. Welsh, T.J. Yen, B. Land, J.C. Hittle, M. McClelland, S. Gay, J. Scholmerich, U. Muller-Ladner, Arthritis Res., 1, 1, 1999, pp 71-80.
  21. Screening Differential Displayed PCR Products by Single-stranded Conformation Polymorphism Gels; F. Mathieu-Daude, N.R. Benson, F. Kullmann, R. Honeycutt, M. McClelland, J. Welsh, PCR Applications: Protocols for Genomics, M. A. Innis, D. H. Gelfand, J.J. Sninsky (Eds.), Academic Press, 1999.
Ramsey, John M.

Devices for High Throughput Cellular Protein Analysis

[ Expand Publications ]

  1. On-Chip Proteolytic Digestion and Analysis Using Wrong-Way-Round Electrospray Time-of-Flight Mass Spectrometry; I. M. Lazar, R. S. Ramsey, J. M. Ramsey, Analytical Chemistry, Vol 73, No 8, 2001, pp 1733-1739.
  2. Integrated Microchip Device for the Digestion, Separation, and Postcolumn Labeling of Proteins and Peptides; N. Gottschlich, C. T. Culbertson, T. E. McKnight, S. C. Jacobson, J. M. Ramsey, Journal of Chromatography B, Vol 745, 2000, pp 243-249.
  3. A Microfabricated Fluidic Device for Performing Two-Dimensional Liquid-Phase Separations; R. D. Rocklin, R. S. Ramsey, J. M. Ramsey, Analytical Chemistry, Vol 72, No 21, 2000, pp 5244-5249.
  4. Electrophoretic Separation of Proteins on a Microchip with Noncovalent Postcolumn Labeling; Y. Liu, R. S. Foote, S. C. Jacobson, R. S. Ramsey, J. M. Ramsey, Analytical Chemistry, Vol 72, No 19, 2000, pp 4608-4613.
  5. Electrophoretic Separation of Proteins on Microchips; Y. Liu, R. S. Foote, C. T. Culbertson, S. C. Jacobson, R. S. Ramsey, J. M. Ramsey, Journal of Microcolumn Separations, Vol 12, No 7, 2000, pp 407-411.
Shackney, Stanley E.

Molecular Profiling of Cells by Laser Scanning Cytometry

[ Expand Publications ]

  1. Multiparameter Analysis of Human Epithelial Tumors by Laser Scanning Cytometry; A.A. Pollice, C.A. Smith, K. Brown, D.L. Farkas, J.F. Silverman, S.E. Shackney, Communications in Clinical Cytometry, 42, 2000, pp 347-356.
  2. Reconstruction of Geno- phenotypic Evolutionary Sequences from Intracellular Patterns of Molecular Abnormalities in Human Solid Tumors; S.E. Shackney, C.A. Smith, A.A. Pollice, and J.F. Silverman In Methods in Molecular Medicine: Lung Cancer. Driscoll, B., (Ed.), In press, Humana Press, 2001.
Sherry, A. D.

MRI Agents Sensitive to Biological Indicators of Neoplasm

[ Expand Publications ]

  1. Lanthanide-DOTA-bis(amide) Complexes: Direct NMR Evidence for Differences in Water Molecule Exchange Rates for Coordination Isomers; S. Zhang, Z. Kovacs, S. Burgess, S. Aime, E. Terreno, A.D. Sherry, Chem. Eur. J., 7, 2001, pp 288-296.
  2. Gd3+ Complexes with Slowly Exchanging Bound Water Molecules May Offer Advantages in the Design of Functional MRI Agents; S. Zhang, K. Wu, A.D. Sherry, Invest. Radiol., 36, 2001, pp 82-86.
  3. A Novel Europium(III)-Based MR Contrast Agent; S. Zhang, P.A. Winter, K. Wu, AlDl Sherry, J. Amer. Chem. Soc., 123, 2001, pp 1517-1518.
  4. 1H and 17O NMR Detection of A Lanthanide-bound Water Molecule at Ambient Temperatures in Pure Water as Solvent; S. Zhang, K. Wu, M.C. Biewer, A.D. Sherry, Inorg. Chem., in press.
Smith, Richard D.

High Throughput FTICR for Molecular Analysis of Cancer

[ Expand Publications ]

  1. Quantitative Analysis of Bacterial and Mammalian Proteomes Using a Combination of Cysteine Affinity Tags and 15N-Metabolic Labeling; T. P. Conrads, K. Alving, T. D. Veenstra, M. E. Belov, G. A. Anderson, D. J. Anderson, M. S. Lipton, L. Pasa-Tolic, H. R. Udseth, W. B. Chrisler, B. D. Thrall, R. D. Smith, Anal. Chem., Vol 73, No 9, 2001, pp 2132-2139.
  2. Phosphoprotein Isotope-coded Affinity Tag (PhIAT) Approach for Isolating and Quantitating Phosphopeptides in Proteome-wide Analyses; M. B. Goshe, T. P. Conrads, E. A. Panisko, N. H. Angell, T. D. Veenstra, R. D. Smith, Anal. Chem., in press.
  3. Ion Discrimination During Ion Accumulation in a Quadrupole Interface External to a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer; M. E. Belov, E. N. Nikolaev, R. Harkewicz, C. D. Masselon, K. Alving and R. D. Smith, Int. J. Mass Spec., in press.
  4. Probing Proteomes-Seeing the Whole Picture; R. D. Smith, Nature Biotech., Vol 18, 2000, pp 1041-2.
  5. Two Dimensional Electrophoretic/Chromatographic Separations Combined with Electrospray Ionization-FTICR Mass Spectrometry for High Throughput Proteome Analysis; H. Gao, Y. Shen, T. D. Veenstra, R. Harkewicz, G. A. Anderson, J. E. Bruce, L. Pasa-Tolic, R. D. Smith, J. Microcolumn Separations, Vol 12, 2000, pp 383-390.
  6. Obtaining More Accurate FTICR Mass Measurements Without Internal Standards Using Multiply Charged Ions; J. E. Bruce, G. A. Anderson, M. D. Brands, L. Pasa-Tolic, R. D. Smith, J. Amer. Soc. Mass Spectrom., Vol 11, 2000, pp 416-421.
  7. Utility of Accurate Mass Tags for Proteome-Wide Protein Identification, T.P. Conrads, G.A. Anderson, T.D. Veenstra, L. Pasa-Tolic, R.D. Smith, Anal. Chem., Vol 72, 2000, pp 3349-3354.
  8. High-Efficiency Capillary Isoelectric Focusing of Peptides; Y. Shen, S.J. Berger, G.A. Anderson, R.D. Smith, Anal. Chem., Vol 72, 2000, pp 2154-2159.
Stanton, Martin

Aptamer Based Detector to Quantity Macromolecules

[ Expand Publications ]

  1. Aptamer Beacons for the Direct Detection of Proteins; N. Hamaguchi, A. Ellington, M. Stanton M., Anal Biochem, 294, 2, 2001, pp 126-31.
Strauss, William M.

Evaluation of Sequence Specific Changes in Genomic DNA

[ Expand Publications ]

  1. Unique Chromosome Identification and Sequence-Specific Structural Analysis Using Short PNA Oligomers. Mammalian Genome; C. Chen, T. Wei, M. Egholm, W.M. Strauss. 11, 2000, 384-391.
  2. Murine Xist RNA Isoforms Are Different at Their 3' Ends: A Role for Differential Polyadenylation; E. Memili, Y-K. Hong, D. K. Kim, S.D. Ontiveros, W.M. Strauss, Gene, 266, 2001, pp 131-137.
  3. Development of Two Bacterial Artificial Chromosome Shuttle Vectors for a Recombination-based Cloning and Regulated Expression of Large Genes in Mammalian Cells; Y-K. Hong, D-H. Kim, A. Beletskii, C. Lee, E. Memili, W. M. Strauss, Analytical Biochemistry, 291, 2001, pp 142-148.
  4. PNA Interference Mapping Demonstrates Functional Domains in the Non-coding RNA Xist; A. Beletskii, Y-K. Hong, J. Pehrson, M. Egholm, W.M. Strauss, PNAS USA. In Press.
Tung, Ching-Hsuan

in vivo Imaging of Matrix Metalloprotease

[ Expand Publications ]

  1. in vivo Molecular Target Assessment of MMP-2 Inhibition; C. Bremer, C.H. Tung, R. Weissleder, Nature Medicine, June, 2001.
Vidal, Marc

New Technologies for Protein Interaction Mapping

[ Expand Publications ]

  1. Protein Interaction Mapping in C. Elegans Using Proteins Involved in Vulval Development; A.J.M. Walhout, R. Sordella, X. Lu, J. Hartley, G. Temple, M. Brasch, N. Thierry-Mieg, M. Vidal, Science, Vol 287, 2000, pp 116-122.
  2. Protein Interaction Maps for Model Organisms; A.J.M. Walhout, M. Vidal, Nature Reviews in Molecular and Cell Biology, 2, 2001, pp 55-62.
  3. Protein Interaction Mapping in C. Elegans Using Proteins Involved in Vulval Development; A.J.M. Walhout, R. Sordella, X. Lu, J. Hartley, G. Temple, M. Brasch, N. Thierry-Mieg, M. Vidal, Science, 287, 2000, pp 116-122.
  4. Gateway Recombinational Cloning: Application to the Cloning of Large Numbers of Open Reading Frames or ORFeomes; A.J.M. Walhout, G.F. Temple, M.A. Brasch, J.L. Hartley, M.A. Lorson, S. van den Heuvel, M. Vidal, Methods in Enzymology 328, 2000, pp575-592.
  5. A Green Fluorescent Protein-Based Reverse Two-Hybrid System: Application to the Characterization of Large Numbers of Potential Protein-Protein Interactions, H.Endoh, A.J.M. Walhout, M. Vidal, Methods in Enzymology, 328, 2000, pp 74-88.
  6. Yeast Two-Hybrid Systems and Protein Interaction Mapping Projects for Yeast and Worm; A.J.M. Walhout, S. Boulton, M. Vidal, Comparative and Functional Genomics (Yeast), 17, 2000, pp 88-94.
  7. Open-Reading-Frame Sequence Tags (OSTs) Support the Existence of at Least 17,300 Genes in C. Elegans; J. Reboul, P. Vaglio, N. Tzellas, N. Thierry-Mieg, E. Lamesch, D. E. Hill, M. Vidal, Nature Genetics, 27, 2001, pp 332-336.
  8. Gateway Recombinational Cloning: Application to the Cloning of Large Numbers of Open Reading Frames or ORFeomes; A.J.M. Walhout, G.F. Temple, M.A. Brasch, J.L. Hartley, M.A. Lorson, S. van den Heuvel, M. Vidal, Methods in Enzymology, Vol 328, 2000, pp 575-592.
  9. A Green Fluorescent Protein-based Reverse Two-hybrid System: Application to the Characterization of Large Numbers of Potential Protein-protein Interactions; H. Endoh, A.J.M. Walhout, M. Vidal, Methods in Enzymology, Vol 328, 2000, pp 74-88.
  10. Open-reading-frame Sequence Tags (OSTs) Support the Existence of at Least 17,300 Genes in C. elegans; J. Reboul, P. Vaglio, N. Tzellas, N. Thierry-Mieg, T. Moore, C. Jackson, T. Shin-i, Y. Kohara, J. Thierry-Mieg, D. Thierry-Mieg, H. Lee, J. Hitti, L. Doucette-Stamm, J. L. Hartley, G. F. Temple, M. A. Brasch, J. Vandenhaute, E. Lamesch, D. E. Hill, M. Vidal, Nature Genetics, Vol 27, 2001, pp 332-336.
Wang, Yue J.

Intelligent Mapping of Gene Expression Profiles

[ Expand Publications ]

  1. Probabilistic Principal Component Subspaces: A Hierarchical Finite Mixture Model for Data Visualization; Y. Wang, L. Luo, M. T. Freedman, S-Y. Kung, IEEE Transactions on Neural Networks, Vol. 11, No. 3, 2000, pp. 625-636.
  2. Discriminative Mining of Gene Microarray Data; J. Lu, Y. Wang, Z. Wang, J. Xuan, S-Y. Kung, Z. Gu, R. Clarke, Proceedings of the IEEE Neural Networks for Signal Processing, 2001, pp. 218-227.
  3. Hierarchy of Probabilistic Principal Component Subspaces for Data Mining; L. Luo, Y. Wang, S-Y. Kung, Proceedings of the IEEE Neural Networks for Signal Processing, 1999, pp 497-506.
  4. Computer-Based Decision Support System: Visual Mapping of Featured Database in Computer-Aided Diagnosis; Y. Wang, Z. Wang, L. Luo, S-H B. Lo, M.T. Freedman, Proceedings of SPIE Medical Imaging, Vol 3979-1, No 24, 2000, pp 136-147.
Wigler, Michael

High Density Gene Copy Number Microarrays

[ Expand Publications ]

  1. Detecting Gene Copy Number Fluctuations in Tumor Cells by Microarray Analyis of Genomic Representations; R. Lucito, J. West, A. Reiner, J. Alexander, D. Esposito, B. Mishra, S. Powers, L. Norton, M. Wigler, Genome Research, 10, 2000, pp 1726-1736.
Wiktor, Peter J.

Piezo Electric Pipetting Technology for DNA Analysis

[ Expand Publications ]

  1. Piezoelectric Pipetting Device; P. Wiktor, U.S. Patent 6,232,129, May 15, 2001.
Wind, Robert A.

An Integrated Confocal and Magnetic Resonance Microscope for Cellular

[ Expand Publications ]

  1. An Integrated Confocal and Magnetic Resonance Microscope for Cellular Research; R.A. Wind, K.R. Minard, G.R. Holtom, P.D. Majors, E.J. Ackerman, S.D. Colson, D.G. Cory, D.S. Daly, P.D. Ellis, N.F. Metting, C.I. Parkinson, J.M. Price, and X.-W. Tang, J. Magn. Reson. Vol 147, 2000, pg 371-377.


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