Related NIH Programs
National Institutes of Health (NIH)
NIH Roadmap Initiatives
The NIH Roadmap Initiative is a large-scale program designed to fill in gaps in biomedical knowledge to speed discovery and clinical application. The NIH Roadmap identifies the most compelling opportunities in three main areas: new pathways to discovery, research teams of the future, and re-engineering the clinical research enterprise. The programs "Building Blocks, Biological Pathways and Networks," "Structural Biology" and "Bioinformatics and Computational Biology" are geared towards better defining the proteome during health and disease.
National Heart, Lung and Blood Institute Proteomics Initiative (NHLBI)
The goal of this initiative is to establish local, highly interactive, multidisciplinary Centers to enhance and develop innovative proteomic technologies and apply them to relevant biological questions in a manner that will advance our knowledge of heart, lung, blood, and sleep health and disease.
National Institutes of Allergy and Infectious Diseases Biodefense Proteomics Research Centers (NIAID)
These research centers are designed to provide comprehensive genomic, proteomic, and bioinformatic resources to the scientific community, which in turn will benefit the nation's biodefense needs, especially in terms of emerging/re-emerging disease. The research programs will discover targets for potential candidates for the next generation of vaccines, therapeutics, and diagnostics.
Also see the Administrative Resource for Biodefense Proteomic Centers.
National Institute of Arthritis and Musculoskeletal and Skin Diseases Muscle Proteomics and Nanotechnology Section (NIAMS)
The laboratory of Dr. Kuan Wang is dedicated to understanding the mechanics of muscle activity, focusing on the large proteins associated with muscle. Dr. Wang's work also utilizes nanotechnology to study muscle activity at the single molecule and single filament level.
National Institute of General Medicine Sciences Structural Genomics and Proteomics Technology Branch and Protein Structure Initiative (NIGMS)
The Structural Genomics and Proteomics Technology Branch uses genomics and computational biology to create protein structures and models to better understand the roles of various proteins in health and disease. The Protein Structure Initiative is a multi-center effort to reduce the time and cost associated with creating protein structures for structure-function studies as they relate to disease. By using the appropriate DNA sequences to create three-dimensional atomic structures of proteins, a long-term goal of this project is to create structure-based therapeutics.
