Summaries & Associations of Study Results
TR-340 Iodinated Glycerol
Target Organs and Levels of Evidence
NTP Technical Report Number 340
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| IODINATED GLYCEROL 5634-39-9 |
10/04/88 | MUCOLYTIC-EXPECTORANT IN RESPIRATORY TRACT CONDITIONS. (TDB) | Gavage FR&FM: 0, 62, 125, MR&MM: 0, 125, 250 MG/KG/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: SOME EVIDENCE | HEMATOPOIETIC SYSTEM: LEUKEMIA 14/50 29/50 24/50 | |||
| THYROID GLAND FOLLICULAR CELL: CARCINOMA 0/49 5/49 1/49 | ||||
| MAY HAVE BEEN RELATED: | NASAL CAVITY: ADENOMA 0/48 0/47 2/49 | |||
| NON-NEOPLASTIC LESIONS: | SALIVARY GLAND: ATROPHY, FOCAL 1/48 10/50 30/49; METAPLASIA, SQUAMOUS 0/48 47/50 48/49 | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | SALIVARY GLAND: ATROPHY, FOCAL 0/49 4/50 11/50; METAPLASIA, SQUAMOUS 1/49 48/50 49/50 | |||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | THYROID GLAND: HYPERPLASIA, FOLLICULAR CELL 3/48 46/50 34/50; DILATATION, FOLLICLE 0/48 28/50 32/50 | |||
| FM: SOME EVIDENCE | PITUITARY GLAND: ADENOMA 10/47 15/45 24/46 | |||
| HARDERIAN GLAND: ADENOMA 6/50 8/40 13/50 OR CARCINOMA 0/50 0/40 1/50 COMBINED 6/50 8/40 14/50 | ||||
| MAY HAVE BEEN RELATED: | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 1/49 2/50 5/49 | |||
| NON-NEOPLASTIC LESIONS: | THYROID GLAND: HYPERPLASIA, FOLLICULAR CELL 2/48 25/48 35/48; DILATATION, FOLLICLE 4/48 11/48 10/48 | |||
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