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UGID:682966     UniGene Hs.467807     Homo sapiens (human)   LAPTM4A
Lysosomal protein transmembrane 4 alpha (LAPTM4A)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_955416.1 lysosomal-associated protein transmembrane 4A R. norvegicus 100.0 232
XP_001094983.1 PREDICTED: similar to lysosomal-associated protein transmembrane 4 alpha isoform 2 M. mulatta 100.0 232
XP_001138869.1 PREDICTED: lysosomal-associated protein transmembrane 4 alpha isoform 3 P. troglodytes 100.0 232
NP_055528.1 lysosomal protein transmembrane 4 alpha H. sapiens 100.0 232
XP_532885.1 PREDICTED: similar to lysosomal-associated protein transmembrane 4 alpha C. lupus familiaris 100.0 232
NP_991368.1 lysosomal protein transmembrane 4 alpha B. taurus 100.0 232
NP_999477.1 alpha-stimulatory subunit of GTP-binding protein S. scrofa 100.0 79
NP_032666.2 lysosomal-associated protein transmembrane 4A M. musculus 98.0 298
NP_490817.3 G protein, Subunit Alpha family member (gsa-1) C. elegans 84.8 79
NP_999850.2 lysosomal-associated protein transmembrane 4 alpha D. rerio 84.8 235
NP_001088768.1 hypothetical protein LOC496032 X. laevis 79.7 230
XP_326348.1 GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP2-ALPHA) N. crassa 58.5 82

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; placenta; embryonic tissue; lung; testis; intestine; skin; prostate; pancreas; eye; kidney; uterus; liver; uncharacterized tissue; connective tissue; mammary gland; muscle; ovary; mixed; stomach; ascites; pharynx; adrenal gland; bone marrow; bone; heart; vascular; spleen; esophagus; thymus; mouth; pituitary gland; bladder; blood; thyroid; ear; salivary gland; lymph; cervix; amniotic fluid; parathyroid; adipose tissue; tonsil; trachea; lymph node; umbilical cord; nerve; larynx; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p24.1
UniSTS entry: Chr 2 A005V18
UniSTS entry: Chr 2 G20533
UniSTS entry: Chr 2 RH17379
UniSTS entry: Chr 2 RH25334
UniSTS entry: Chr 2 D2S1999
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (33)

D14696.1 Homo sapiens KIAA0108 mRNA, partial cds P
AK129875.1 Homo sapiens cDNA FLJ26365 fis, clone HRT05805, highly similar to Lysosomal-associated transmembrane protein 4A P
AY359028.1 Homo sapiens clone DNA19360 MTP (UNQ1846) mRNA, complete cds PA
CR456758.1 Homo sapiens full open reading frame cDNA clone RZPDo834C054D for gene LAPTM4A, lysosomal-associated protein transmembrane 4 alpha; complete cds, incl. stopcodon P
CR624947.1 full-length cDNA clone CS0DI025YJ01 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR623001.1 full-length cDNA clone CS0DB006YH03 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
CR622236.1 full-length cDNA clone CS0DI014YN01 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR621170.1 full-length cDNA clone CS0DI068YH19 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR621011.1 full-length cDNA clone CS0DI025YF20 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR619265.1 full-length cDNA clone CS0DI054YI22 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR618630.1 full-length cDNA clone CS0DI076YK12 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR618524.1 full-length cDNA clone CS0DE010YH02 of Placenta of Homo sapiens (human) P
CR615552.1 full-length cDNA clone CS0DE012YJ01 of Placenta of Homo sapiens (human) P
CR613521.1 full-length cDNA clone CS0DK006YH16 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR612473.1 full-length cDNA clone CS0DI069YG06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR611436.1 full-length cDNA clone CS0DI029YG03 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR608072.1 full-length cDNA clone CS0DI028YJ10 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR607830.1 full-length cDNA clone CS0DC014YN01 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR607775.1 full-length cDNA clone CS0DI070YO16 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR607529.1 full-length cDNA clone CS0DI062YK16 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR605678.1 full-length cDNA clone CS0DF023YC17 of Fetal brain of Homo sapiens (human) P
CR604820.1 full-length cDNA clone CS0DI066YP23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604791.1 full-length cDNA clone CS0DI072YL22 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR602246.1 full-length cDNA clone CS0DI043YE18 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR599755.1 full-length cDNA clone CS0DM010YE03 of Fetal liver of Homo sapiens (human) P
CR599013.1 full-length cDNA clone CL0BB006ZD05 of Neuroblastoma of Homo sapiens (human) P
CR597537.1 full-length cDNA clone CS0DE009YG20 of Placenta of Homo sapiens (human) P
CR594890.1 full-length cDNA clone CS0DI008YI05 of Placenta Cot 25-normalized of Homo sapiens (human) P
NM_014713.4 Homo sapiens lysosomal protein transmembrane 4 alpha (LAPTM4A), mRNA PA
BC093075.1 Homo sapiens lysosomal protein transmembrane 4 alpha, mRNA (cDNA clone MGC:111219 IMAGE:30402963), complete cds PA
BC000421.2 Homo sapiens lysosomal protein transmembrane 4 alpha, mRNA (cDNA clone MGC:8667 IMAGE:2964450), complete cds PA
BC003158.1 Homo sapiens lysosomal protein transmembrane 4 alpha, mRNA (cDNA clone MGC:4121 IMAGE:2958870), complete cds PA
AK304433.1 Homo sapiens cDNA FLJ51463 complete cds, highly similar to Lysosomal-associated transmembrane protein 4A P

EST sequences (10 of 1833) [Show all sequences]

AA954650.1 Clone IMAGE:1554897 kidney 3' read A
AA961101.1 Clone IMAGE:1569808 lung 3' read A
AA922617.1 Clone IMAGE:1474245 intestine 3' read A
AA968559.1 Clone IMAGE:1592179 kidney 3' read A
AA971026.1 Clone IMAGE:1575294 kidney 3' read A
AA983367.1 Clone IMAGE:1592727 kidney 3' read A
AA988826.1 Clone IMAGE:1602671 lung 3' read
AI001116.1 Clone IMAGE:1613204 uncharacterized tissue 3' read A
AA886430.1 Clone IMAGE:1501940 kidney 3' read A
AA902824.1 Clone IMAGE:1519171 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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