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ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (ATP8A1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference Protein | Species | Id(%) | Len(aa) |
NP_006086.1 |
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform a |
H. sapiens |
100.0 |
1163 |
XP_001099138.1 |
PREDICTED: similar to ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
M. mulatta |
99.9 |
1163 |
XP_001150768.1 |
PREDICTED: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform 1 |
P. troglodytes |
99.9 |
1163 |
NP_001034088.1 |
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform a |
M. musculus |
98.7 |
1163 |
NP_610873.1 |
CG17034 CG17034-PD, isoform D |
D. melanogaster |
63.9 |
1112 |
NP_001022894.1 |
Transbilayer Amphipath Transporters (subfamily IV P-type ATPase) family member (tat-1) |
C. elegans |
56.6 |
1110 |
XP_322438.1 |
hypothetical protein |
N. crassa |
54.3 |
1117 |
NP_009376.1 |
Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease; Drs2p |
S. cerevisiae |
51.3 |
1118 |
XP_691903.2 |
PREDICTED: similar to Potential phospholipid-transporting ATPase ID (ATPase class I type 8B member 2) |
D. rerio |
47.9 |
1100 |
NP_176191.1 |
haloacid dehalogenase-like hydrolase family protein |
A. thaliana |
47.8 |
1101 |
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
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Expression Profile: | View expression levels using UniGene's EST ProfileViewer [Show more entries with profiles like this] |
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GEO profiles: |
Gene expression profiles in the NCBI Gene Expression Omnibus database |
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cDNA Sources: |
brain; uncharacterized tissue; embryonic tissue; eye; kidney; pancreas; lymph node; mixed; muscle; prostate; pharynx; placenta; adrenal gland; pituitary gland; blood; mouth; esophagus; spleen; thymus; parathyroid; vascular; liver; intestine; uterus; testis; connective tissue; ear; lymph; skin; nerve; stomach; lung; ovary; bone; adipose tissue; pineal gland |
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
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Chromosome: |
4 |
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Map position: |
4p14-p12 |
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UniSTS entry: |
Chr 4 |
D4S3277 |
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UniSTS entry: |
Chr 4 |
SHGC-59604 |
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UniSTS entry: |
Chr 4 |
(n/a) |
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UniSTS entry: |
Chr 4 |
WI-19830 |
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SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.
mRNA sequences (12)
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AB013452.1 |
Homo sapiens mRNA for ATPaseII, complete cds |
P |
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BX648675.1 |
Homo sapiens mRNA; cDNA DKFZp686C1850 (from clone DKFZp686C1850) |
PA |
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AB209687.1 |
Homo sapiens mRNA for ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 variant protein |
P |
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AK027252.1 |
Homo sapiens cDNA: FLJ23599 fis, clone LNG15473, highly similar to AF035315 Homo sapiens clone 23664 and 23905 mRNA sequence |
A |
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BC109318.1 |
Homo sapiens ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, mRNA (cDNA clone MGC:130043 IMAGE:40036538), complete cds |
P |
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BC109317.1 |
Homo sapiens ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, mRNA (cDNA clone MGC:130042 IMAGE:40036536), complete cds |
P |
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NM_006095.2 |
Homo sapiens ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (ATP8A1), transcript variant 1, mRNA |
PA |
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NM_001105529.1 |
Homo sapiens ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (ATP8A1), transcript variant 2, mRNA |
PA |
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AK295616.1 |
Homo sapiens cDNA FLJ61275 complete cds, highly similar to Probable phospholipid-transporting ATPase IA(EC 3.6.3.1) |
P |
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BC020943.1 |
Homo sapiens ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, mRNA (cDNA clone IMAGE:4816327), complete cds |
PA |
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AF067820.1 |
Homo sapiens ATPase II mRNA, partial cds |
P |
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AF035315.1 |
Homo sapiens clone 23664 and 23905 mRNA sequence |
A |
EST sequences (10 of 253) [Show all sequences]
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AI026127.1 |
Clone IMAGE:1647356 |
parathyroid |
3' read |
A |
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AI033689.1 |
Clone IMAGE:1647978 |
parathyroid |
3' read |
A |
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AI041510.1 |
Clone IMAGE:1648865 |
parathyroid |
3' read |
A |
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BX089396.1 |
Clone IMAGp998B2474_;_IMAGE:23877 |
brain |
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A |
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BX089438.1 |
Clone IMAGp998D03730_;_IMAGE:322514 |
parathyroid |
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AI204896.1 |
Clone IMAGE:1684742 |
brain |
3' read |
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AI218581.1 |
Clone IMAGE:1845168 |
mixed |
3' read |
A |
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AI267759.1 |
Clone IMAGE:2022328 |
brain |
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R38285.1 |
Clone IMAGE:23877 |
brain |
3' read |
A |
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AI367652.1 |
Clone IMAGE:1934553 |
embryonic tissue |
3' read |
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Key to Symbols
P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria
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