Poly(A) binding protein, cytoplasmic 1, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented in many libraries

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; intestine; uncharacterized tissue; embryonic tissue; mammary gland; skin; testis; mixed; prostate; eye; uterus; lung; stomach; blood; pancreas; liver; kidney; connective tissue; bone; vascular; larynx; lymph node; mouth; ovary; placenta; cervix; bone marrow; thymus; lymph; bladder; thyroid; muscle; pharynx; ascites; spleen; ear; heart; tonsil; salivary gland; trachea; adrenal gland; esophagus; nerve; amniotic fluid; pituitary gland; epididymis; ganglia; adipose tissue; umbilical cord; parathyroid

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Finding cDNAs

UGID:206887 UniGene Hs.387804 Homo sapiens (human) PABPC1

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Poly(A) binding protein, cytoplasmic 1 (PABPC1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001927782.1	PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1)	S. scrofa	100.0	635
NP_776993.1	poly(A) binding protein, cytoplasmic 1	B. taurus	100.0	635
NP_001085456.1	MGC80109 protein	X. laevis	98.2	57
NP_003324.1	ubiquitin and ribosomal protein L40 precursor	H. sapiens	98.2	57
NP_683717.1	poly(A) binding protein, cytoplasmic 4 isoform 2	M. musculus	90.7	614
NP_725749.1	polyA-binding protein CG5119-PB, isoform B	D. melanogaster	74.0	633
NP_001021710.1	PolyA Binding protein family member (pab-1)	C. elegans	67.0	576
XP_960425.1	polyadenylate-binding protein	N. crassa	56.0	713

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	8
	Map position:	8q22.2-q23

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK130523.1	Homo sapiens cDNA FLJ27013 fis, clone SLV05396, highly similar to Polyadenylate-binding protein 1	P
NM_002568.3	Homo sapiens poly(A) binding protein, cytoplasmic 1 (PABPC1), mRNA	PA
AK057080.1	Homo sapiens cDNA FLJ32518 fis, clone SMINT1000118
BC015958.2	Homo sapiens poly(A) binding protein, cytoplasmic 1, mRNA (cDNA clone MGC:15290 IMAGE:3940309), complete cds	PA
AK298990.1	Homo sapiens cDNA FLJ59219 complete cds, highly similar to Poly(A)-binding protein 1
AK303120.1	Homo sapiens cDNA FLJ57246 complete cds, highly similar to Poly(A)-binding protein 1
BC023217.1	Homo sapiens cDNA clone IMAGE:4522410	PA
Z48501.1	H.sapiens mRNA for polyadenylate binding protein II	P
Y00345.1	Human mRNA for polyA binding protein	P
BC023520.2	Homo sapiens poly(A) binding protein, cytoplasmic 1, mRNA (cDNA clone MGC:12727 IMAGE:4123269), complete cds	PA

EST sequences (10 of 4622) [Show all sequences]

AA961112.1	Clone IMAGE:1569807	lung	3' read	A
AA962698.1	Clone IMAGE:1575469	intestine	3' read	P
AA971022.1	Clone IMAGE:1582045	mixed	3' read	A
AA978233.1	Clone IMAGE:1273938	bone
AA987995.1	Clone IMAGE:1604387	lung	3' read	A
AA988483.1	Clone IMAGE:1603007	lung	3' read	A
R16426.1	Clone IMAGE:129325	mixed	5' read	P
AI015336.1	Clone IMAGE:1618790	testis	3' read	A
AI022806.1	Clone IMAGE:1650760	parathyroid	3' read
R18798.1	Clone IMAGE:27347	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria