Testing Status of Agents at NTP
Nickel subsulfide
CASRN: 12035-72-2
Related: NICKEL SULFATE HEXAHYDRATE (10101-97-0)
Formula: NI3-S2
Synonyms/Common Names:
- NICKEL SULFIDE
Known Uses:
MAJOR COMPONENT IN NICKEL REFINERY FLUE DUST. NOT USED COMMERCIALLY IN U.S. (TDB)
Short-Term Toxicity
- 2-WEEK (Inhalation)
(C61654) Completed
- (Peer Review 11/29/1994) Citation: Benson JM, Barr EB, Bechtold WE, Cheng YS. Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats. Inhalation Toxicology, 6:167-183, 1994.
- NTIS No. PB97-116784
(Peer Review 11/29/1994)
Citation: Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CAS No. 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies) - (Peer Review 11/29/1994) Citation: Benson JM, Barr EB, Bechtold WE, Cheng YS. Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats. Inhalation Toxicology, 6:167-183, 1994.
- NTIS No. PB97-116784
(Peer Review 11/29/1994)
Citation: Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CAS No. 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, 0.6, 1.2, 2.5, 5, OR 10 MG/MG; 5/GROUP
- 13-WEEK (Inhalation)
(C61654) Completed
- (Peer Review 11/29/1994) Citation: Benson JM, Barr EB, Bechtold WE, Cheng YS. Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats. Inhalation Toxicology, 6:167-183, 1994.
- NTIS No. PB97-116784
(Peer Review 11/29/1994)
Citation: Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CAS No. 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies) - (Peer Review 11/29/1994) Citation: Benson JM, Barr EB, Bechtold WE, Cheng YS. Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats. Inhalation Toxicology, 6:167-183, 1994.
- NTIS No. PB97-116784
(Peer Review 11/29/1994)
Citation: Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CAS No. 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, .15, OR 2.5 MG/M3; 10/GROUP
Long-Term Carcinogenicity
- 2-YEAR (Inhalation)
(C61654) Report Complete
- (Peer Review 11/29/1994) Citation: Benson JM, Barr EB, Bechtold WE, Cheng YS. Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats. Inhalation Toxicology, 6:167-183, 1994.
- TR-453 (NTIS No. PB97-116784)
(Peer Review 11/29/1994)
Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CAS No. 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies) - (Peer Review 11/29/1994) Citation: Benson JM, Barr EB, Bechtold WE, Cheng YS. Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats. Inhalation Toxicology, 6:167-183, 1994.
- TR-453 (NTIS No. PB97-116784)
(Peer Review 11/29/1994)
Toxicology and Carcinogenesis Studies of Nickel Subsulfide (CAS No. 12035-72-2) in F344 Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Clear Evidence
- Female Rats Clear Evidence
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: R: 0, 0.075, OR 0.15 M: 0, 0.6, OR 1.2 MG/M3; 50/GROUP
Genetic Toxicology
- Micronucleus
(A50848) Completed
- Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
- Mice: B6C3F1
- Male Negative
- Female Negative
- Salmonella
(498230) Completed
- Inconclusive
Web page last updated on January 22, 2009