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UGID:231605     UniGene Hs.436568     Homo sapiens (human)   CD74
CD74 molecule, major histocompatibility complex, class II invariant chain (CD74)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_004346.1 CD74 antigen isoform b H. sapiens 100.0 231

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in many libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; tonsil; uncharacterized tissue; spleen; intestine; lymph; lung; lymph node; thymus; connective tissue; ovary; pancreas; heart; stomach; uterus; placenta; blood; liver; eye; mammary gland; adipose tissue; mixed; bone; muscle; thyroid; adrenal gland; prostate; kidney; cervix; bone marrow; ganglia; vascular; bladder; skin; salivary gland; pharynx; testis; pituitary gland; esophagus; ascites; trachea; mouth; parathyroid; nerve; umbilical cord; embryonic tissue; epididymis; ear; peritoneum; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q32
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (28)

K01144.1 Human major histocompatibility class II antigen gamma chain mRNA, complete cds P
CR625117.1 full-length cDNA clone CS0DI034YG14 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR622356.1 full-length cDNA clone CS0CAP001YB13 of Thymus of Homo sapiens (human) P
CR621994.1 full-length cDNA clone CS0DI070YH04 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR621213.1 full-length cDNA clone CS0CAP008YM10 of Thymus of Homo sapiens (human) P
CR619151.1 full-length cDNA clone CS0DI034YA09 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR616774.1 full-length cDNA clone CS0DG006YF19 of B cells (Ramos cell line) of Homo sapiens (human) P
CR615386.1 full-length cDNA clone CS0DI017YH17 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR608306.1 full-length cDNA clone CS0CAP007YL12 of Thymus of Homo sapiens (human) P
CR608107.1 full-length cDNA clone CS0DI007YC04 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604165.1 full-length cDNA clone CS0DG003YD02 of B cells (Ramos cell line) of Homo sapiens (human) P
CR601246.1 full-length cDNA clone CS0DI057YM17 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR596915.1 full-length cDNA clone CS0DI046YA22 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR595353.1 full-length cDNA clone CS0DI021YO13 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR594737.1 full-length cDNA clone CS0DL004YA10 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human)
CR590167.1 full-length cDNA clone CS0DI003YE05 of Placenta Cot 25-normalized of Homo sapiens (human) P
BT019505.1 Homo sapiens CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) mRNA, complete cds P
NM_001025159.1 Homo sapiens CD74 molecule, major histocompatibility complex, class II invariant chain (CD74), transcript variant 1, mRNA P
NM_001025158.1 Homo sapiens CD74 molecule, major histocompatibility complex, class II invariant chain (CD74), transcript variant 3, mRNA P
NM_004355.2 Homo sapiens CD74 molecule, major histocompatibility complex, class II invariant chain (CD74), transcript variant 2, mRNA P
BC018726.1 Homo sapiens CD74 molecule, major histocompatibility complex, class II invariant chain, mRNA (cDNA clone MGC:31825 IMAGE:4853578), complete cds P
AK292076.1 Homo sapiens cDNA FLJ75773 complete cds, highly similar to Homo sapiens CD74 antigen (invariant polypeptide of majorhistocompatibility complex, class II antigen-associated) (CD74),mRNA
AK308929.1 Homo sapiens cDNA, FLJ98970
BC024272.1 Homo sapiens CD74 molecule, major histocompatibility complex, class II invariant chain, mRNA (cDNA clone MGC:39144 IMAGE:4763768), complete cds P
AK300669.1 Homo sapiens cDNA FLJ54063 complete cds, highly similar to Homo sapiens CD74 antigen, transcript variant 2, mRNA
AK297889.1 Homo sapiens cDNA FLJ56699 complete cds, highly similar to HLA class II histocompatibility antigen gamma chain
X00497.1 Human mRNA for HLA-DR antigens associated invariant chain (p33) P
M28590.1 Human (clone pcDG-79) MHC HLA-DG protein 41 mRNA, partial cds

EST sequences (10 of 6438) [Show all sequences]

AA866070.1 Clone IMAGE:1459443 kidney 3' read P
AA962713.1 Clone IMAGE:1575483 intestine 3' read
AA972496.1 Clone IMAGE:1575721 intestine 3' read
AA970269.1 Clone IMAGE:1575193 kidney 3' read
AA970814.1 Clone IMAGE:1576524 intestine 3' read
AA971409.1 Clone IMAGE:1584294 lung 3' read
AA985611.1 Clone IMAGE:1593034 kidney 3' read
AA988698.1 Clone IMAGE:1594013 kidney 3' read
AA996253.1 Clone IMAGE:1605705 kidney 3' read
AI000310.1 Clone IMAGE:1613953 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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