Low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (2.6 pct) in cDNA library dbEST:6365, FN0106.

Highly represented (1.3 pct) in cDNA library dbEST:7909, EN0086.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; uncharacterized tissue; placenta; lung; embryonic tissue; connective tissue; muscle; pancreas; eye; uterus; bone; intestine; prostate; mammary gland; mixed; ovary; testis; mouth; kidney; skin; stomach; heart; trachea; vascular; blood; spleen; liver; nerve; larynx; adipose tissue; pharynx; thymus; epididymis; ganglia; pituitary gland; cervix; spinal cord; thyroid; salivary gland

NCBI

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Finding cDNAs

UGID:156459 UniGene Hs.162757 Homo sapiens (human) LRP1

Links

Low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (LRP1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001056970.1	PREDICTED: similar to low density lipoprotein receptor-related protein 1	R. norvegicus	98.4	4544
NP_001018066.1	very low density lipoprotein receptor isoform b	H. sapiens	45.1	734

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	12
	Map position:	12q13-q14

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BC045107.1	Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), mRNA (cDNA clone IMAGE:4859182), complete cds	PA
BC052593.1	Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), mRNA (cDNA clone IMAGE:6575284), complete cds	PA
NM_002332.2	Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (LRP1), mRNA	A
BC072015.1	Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), mRNA (cDNA clone IMAGE:6384902), complete cds	PA
AB209498.1	Homo sapiens mRNA for low density lipoprotein-related protein 1 variant protein	P
EF491814.1	Homo sapiens clone LRP1 mRNA, partial sequence; alternatively spliced
EF491795.1	Homo sapiens clone LRP1 mRNA, partial sequence; alternatively spliced
X13916.1	Human mRNA for LDL-receptor related protein	PA
BC021204.2	Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), mRNA (cDNA clone IMAGE:4110815), complete cds	PA
X55077.1	H.sapiens mRNA fragment for alpha-2 macroglobulin receptor	P

EST sequences (10 of 1016) [Show all sequences]

AA903682.1	Clone IMAGE:1517729	uncharacterized tissue	3' read	A
AA968513.1	Clone IMAGE:1575002	kidney	3' read	A
AA970647.1	Clone IMAGE:1574518	kidney	3' read
R14915.1	Clone IMAGE:30219	brain	5' read
AA902301.1	Clone IMAGE:1519742	uncharacterized tissue	3' read
AI004371.1	Clone IMAGE:1624529	embryonic tissue	3' read
AI022443.1	Clone IMAGE:1654708	mixed	3' read
AI027631.1	Clone IMAGE:1645459	testis	3' read
AI040093.1	Clone IMAGE:1659937	embryonic tissue	3' read
T27079.1	Clone LLAB258B01	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria