Guanine nucleotide binding protein (G protein), beta polypeptide 3, Homo sapiens

Restricted Expression:

eye [show more like this]

retinoblastoma [show more like this]

adult [show more like this]

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

eye; brain; uncharacterized tissue; lung; pituitary gland; pineal gland; mixed; muscle; placenta; connective tissue; pancreas; heart

NCBI

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Finding cDNAs

UGID:2138551 UniGene Hs.631657 Homo sapiens (human) GNB3

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Guanine nucleotide binding protein (G protein), beta polypeptide 3 (GNB3)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001110494.1	PREDICTED: guanine nucleotide-binding protein, beta-3 subunit isoform 3	M. mulatta	100.0	339
NP_727907.1	G protein beta-subunit 13F CG10545-PB, isoform B	D. melanogaster	83.8	339
NP_006569.1	guanine nucleotide-binding protein, beta-5 subunit isoform a	H. sapiens	58.6	341
NP_974683.1	AGB1 (GTP BINDING PROTEIN BETA 1); nucleotide binding	A. thaliana	51.7	319

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	12
	Map position:	12p13

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BT009800.1	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3 mRNA, complete cds	P
NM_002075.2	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3 (GNB3), mRNA	P
M31328.1	Human guanine nucleotide-binding protein beta-3 subunit mRNA, complete cds	P
AB209283.1	Homo sapiens mRNA for guanine nucleotide-binding protein, beta-3 subunit variant protein	P
BC002454.2	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3, mRNA (cDNA clone MGC:1738 IMAGE:3342882), complete cds	PA
BC000115.1	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3, mRNA (cDNA clone MGC:3116 IMAGE:3351520), complete cds	PA
BC015920.1	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3, mRNA (cDNA clone MGC:20430 IMAGE:4648399), complete cds	PA
AK313091.1	Homo sapiens cDNA, FLJ93574
AF501884.1	Homo sapiens guanine nucleotide binding protein beta 3 (GNB3) mRNA, complete cds	P
U47930.1	Human G-protein beta-3 subunit mRNA, partial cds

EST sequences (10 of 144) [Show all sequences]

BX112979.1	Clone IMAGp998F12467_;_IMAGE:231947	pineal gland
CB565934.1	Clone IMAGE:6519164	uncharacterized tissue	5' read	P
CB565933.1	Clone IMAGE:6519165	uncharacterized tissue	5' read	P
AI969125.1	Clone IMAGE:2545720	pituitary gland	3' read	A
AW003591.1	Clone IMAGE:2545512	pituitary gland	3' read
AW026130.1	Clone IMAGE:2528980	brain	3' read
BX490995.1	Clone DKFZp686O1392	muscle	5' read
AW192884.1	Clone IMAGE:2678570	pancreas	3' read
BX953978.1	Clone DKFZp781J2351	uncharacterized tissue	5' read
AW949728.1		uncharacterized tissue		A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria