Splicing factor, arginine/serine-rich 3, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.4 pct) in cDNA library dbEST:3876, PT0009.

Highly represented (1.4 pct) in cDNA library dbEST:7645, CI0186.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; testis; embryonic tissue; lung; uncharacterized tissue; uterus; liver; kidney; pancreas; placenta; mixed; prostate; skin; intestine; mammary gland; blood; eye; bladder; bone marrow; thymus; heart; lymph node; stomach; muscle; esophagus; bone; ovary; connective tissue; salivary gland; vascular; tonsil; lymph; cervix; ascites; pharynx; trachea; adipose tissue; spleen; adrenal gland; mouth; thyroid; ear; larynx; pituitary gland; epididymis; umbilical cord; parathyroid; nerve; ganglia; spinal cord

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Finding cDNAs

UGID:219226 UniGene Hs.405144 Homo sapiens (human) SFRS3

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Splicing factor, arginine/serine-rich 3 (SFRS3)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_038691.1	splicing factor, arginine/serine-rich 3 (SRp20)	M. musculus	100.0	163
NP_001041372.1	splicing factor, arginine/serine-rich 3 (SRp20)	R. norvegicus	100.0	163
XP_001370000.1	PREDICTED: similar to splicing factor, arginine/serine-rich 3,	M. domestica	100.0	163
NP_001005054.1	splicing factor, arginine serine-rich 3	X. tropicalis	100.0	163
XP_417951.1	PREDICTED: hypothetical protein isoform 2	G. gallus	100.0	163
XP_001509029.1	PREDICTED: similar to splicing factor, arginine/serine-rich 3	O. anatinus	100.0	163
XP_001173185.1	PREDICTED: hypothetical protein isoform 2	P. troglodytes	100.0	163
NP_003008.1	splicing factor, arginine/serine-rich 3	H. sapiens	100.0	163
XP_001502755.1	PREDICTED: similar to splicing factor, arginine/serine-rich 3	E. caballus	100.0	163
NP_001029872.1	splicing factor, arginine/serine-rich 3	B. taurus	100.0	163
NP_958480.1	splicing factor, arginine/serine-rich 3b	D. rerio	96.3	162
NP_001080460.1	splicing factor, arginine/serine-rich 3	X. laevis	93.0	157
NP_524307.1	RNA-binding protein 1 CG17136-PA, isoform A	D. melanogaster	70.5	128
NP_741446.1	SR Protein (splicing factor) family member (rsp-6)	C. elegans	55.9	178
XP_001700473.1	SR protein factor	C. reinhardtii	47.5	219

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	6
Map position:	6p21
UniSTS entry:	Chr 11	STS-L10838
UniSTS entry:	Chr 6	RH78275
UniSTS entry:	Chr 6	WI-11748
UniSTS entry:	Chr 6	D6S1788
UniSTS entry:	Chr 7	ECD07635
UniSTS entry:	Chr 6	RH18481
UniSTS entry:	Chr 6	STS-H70468
UniSTS entry:	Chr 19	RH80123

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (32)

BT007017.1	Homo sapiens splicing factor, arginine/serine-rich 3 mRNA, complete cds	P
AL050041.1	Homo sapiens mRNA; cDNA DKFZp566L0424 (from clone DKFZp566L0424)	A
L10838.1	Homo sapiens SR protein family, pre-mRNA splicing factor (SRp20) mRNA, complete cds	P
NM_003017.4	Homo sapiens splicing factor, arginine/serine-rich 3 (SFRS3), mRNA	P
BC069018.1	Homo sapiens splicing factor, arginine/serine-rich 3, mRNA (cDNA clone MGC:78599 IMAGE:3507371), complete cds	PA
CR624897.1	full-length cDNA clone CL0BB019ZF07 of Neuroblastoma of Homo sapiens (human)	P
CR624175.1	full-length cDNA clone CS0DM002YE08 of Fetal liver of Homo sapiens (human)	P
CR622471.1	full-length cDNA clone CS0DI085YL20 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR622370.1	full-length cDNA clone CS0DJ010YP13 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human)	P
CR621558.1	full-length cDNA clone CS0DM008YG16 of Fetal liver of Homo sapiens (human)	P
CR621528.1	full-length cDNA clone CS0DI081YL02 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR617752.1	full-length cDNA clone CL0BB003ZG07 of Neuroblastoma of Homo sapiens (human)	P
CR617139.1	full-length cDNA clone CS0DH005YL05 of T cells (Jurkat cell line) of Homo sapiens (human)	P
CR613674.1	full-length cDNA clone CS0DI041YM08 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR612662.1	full-length cDNA clone CL0BB026ZE07 of Neuroblastoma of Homo sapiens (human)	P
CR612246.1	full-length cDNA clone CS0DH005YG20 of T cells (Jurkat cell line) of Homo sapiens (human)	P
CR611557.1	full-length cDNA clone CS0DI053YC06 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR608185.1	full-length cDNA clone CS0CAP001YK24 of Thymus of Homo sapiens (human)	P
CR601962.1	full-length cDNA clone CS0DG003YC16 of B cells (Ramos cell line) of Homo sapiens (human)	P
CR599518.1	full-length cDNA clone CS0DA003YF09 of Neuroblastoma of Homo sapiens (human)	P
CR599324.1	full-length cDNA clone CS0DI006YI16 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR595256.1	full-length cDNA clone CS0DE011YO18 of Placenta of Homo sapiens (human)	P
AF107405.1	Homo sapiens pre-mRNA splicing factor (SFRS3) mRNA, complete cds	PA
BC000914.1	Homo sapiens splicing factor, arginine/serine-rich 3, mRNA (cDNA clone MGC:5205 IMAGE:3049167), complete cds	PA
AK310317.1	Homo sapiens cDNA, FLJ17359	P
AK312553.1	Homo sapiens cDNA, FLJ92926, Homo sapiens splicing factor, arginine/serine-rich 3 (SFRS3), mRNA	P
AK095580.1	Homo sapiens cDNA FLJ38261 fis, clone FCBBF3001470
AK091927.1	Homo sapiens cDNA FLJ34608 fis, clone KIDNE2013845	P
AK304097.1	Homo sapiens cDNA FLJ52832 complete cds, highly similar to Splicing factor, arginine/serine-rich 3	P
AB451352.1	Homo sapiens SFRS3 mRNA for splicing factor arginine/serine-rich 3, partial cds, clone: FLJ08018AAAF	P
AB451229.1	Homo sapiens SFRS3 mRNA for splicing factor arginine/serine-rich 3, complete cds, clone: FLJ08018AAAN	P
D28423.1	Homo sapiens mRNA for pre-mRNA splicing factor SRp20, 5'UTR region

EST sequences (10 of 2115) [Show all sequences]

AA961285.1	Clone IMAGE:1564523	mixed	3' read
AA962327.1	Clone IMAGE:1569925	lung	3' read	P
AA968739.1	Clone IMAGE:1569954	lung	3' read	A
AA991394.1	Clone IMAGE:1608945	mammary gland	3' read	A
AA995315.1	Clone IMAGE:1606599	kidney	3' read
R20073.1	Clone IMAGE:35020	brain	5' read
AI055930.1	Clone IMAGE:1659168	embryonic tissue	3' read	P
AI061200.1	Clone IMAGE:1700335	kidney	3' read	A
AI080545.1	Clone IMAGE:1680045	skin	3' read	A
AI090300.1	Clone IMAGE:1672210	uncharacterized tissue	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria