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UGID:909272     UniGene Hs.518525     Homo sapiens (human)   GLUL
Glutamate-ammonia ligase (glutamine synthetase) (GLUL)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001114827.1 PREDICTED: glutamine synthetase isoform 1 M. mulatta 100.0 372
XP_001160639.1 PREDICTED: glutamine synthetase isoform 4 P. troglodytes 100.0 372
NP_001028216.1 glutamine synthetase H. sapiens 100.0 372
NP_511123.2 Glutamine synthetase 2 CG1743-PC, isoform C D. melanogaster 74.2 368
NP_503065.1 GLutamiNe synthetase (glutamate-ammonia ligase) family member (gln-5) C. elegans 66.2 366
NP_001078639.1 GS2 (GLUTAMINE SYNTHETASE 2) A. thaliana 62.6 366

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; eye; lung; testis; pharynx; embryonic tissue; uterus; uncharacterized tissue; placenta; mixed; blood; liver; intestine; connective tissue; mammary gland; muscle; prostate; mouth; skin; kidney; nerve; pineal gland; pancreas; spleen; adrenal gland; bone marrow; trachea; stomach; bladder; heart; ganglia; adipose tissue; ovary; thymus; thyroid; larynx; lymph node; ear; spinal cord; bone; ascites; vascular; salivary gland; cervix; epididymis; pituitary gland; esophagus; amniotic fluid; parathyroid; lymph; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q31
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

BC051726.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:48617 IMAGE:5261804), complete cds PA
BX537384.1 Homo sapiens mRNA; cDNA DKFZp686E0382 (from clone DKFZp686E0382); complete cds PA
AK122784.1 Homo sapiens cDNA FLJ16338 fis, clone TESTI2004920, highly similar to GLUTAMINE SYNTHETASE (EC 6.3.1.2) P
NM_002065.4 Homo sapiens glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 1, mRNA P
CR614928.1 full-length cDNA clone CS0DI022YC06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR608505.1 full-length cDNA clone CS0DI078YH15 of Placenta Cot 25-normalized of Homo sapiens (human)
CR607019.1 full-length cDNA clone CS0DI052YG18 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR593676.1 full-length cDNA clone CS0DB001YA05 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
AY486122.1 Homo sapiens glutamine synthetase mRNA, complete cds P
NM_001033044.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 2, mRNA P
NM_001033056.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 3, mRNA P
AY513283.1 Homo sapiens proliferation-inducing protein 43 (PIG43) mRNA, complete cds P
BC127883.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone IMAGE:40131529), partial cds
BC010037.2 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:19730 IMAGE:3545927), complete cds PA
BC011852.2 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:20322 IMAGE:4137547), complete cds PA
BC011700.2 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:19700 IMAGE:3528830), complete cds PA
BC018992.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:20095 IMAGE:3352740), complete cds PA
AY947343.1 Homo sapiens cell proliferation-inducing protein 59 (PIG59) mRNA, complete cds A
AK301600.1 Homo sapiens cDNA FLJ57219 complete cds, highly similar to Glutamine synthetase (EC 6.3.1.2) A
X59834.1 Human rearranged mRNA for glutamine synthase PA
Y00387.2 Human mRNA for glutamine synthetase (EC 6.3.1.2) P
BC031964.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:42945 IMAGE:4837475), complete cds PA
S70290.1 glutamine synthetase [human, tumorous liver, mRNA Partial, 2631 nt] P

EST sequences (10 of 2293) [Show all sequences]

AA960819.1 Clone IMAGE:1552217 uncharacterized tissue 3' read P
AA962786.1 Clone IMAGE:1573461 kidney 3' read
AA922302.1 Clone IMAGE:1474259 intestine 3' read
R15942.1 Clone IMAGE:53028 brain 3' read
R15943.1 Clone IMAGE:53028 brain 5' read P
R15036.1 Clone IMAGE:29470 brain 5' read
AA987234.1 Clone IMAGE:1604252 lung 3' read P
AA993225.1 Clone IMAGE:1625097 embryonic tissue 3' read
AI000103.1 Clone IMAGE:1609836 mammary gland 3' read P
AI002875.1 Clone IMAGE:1699511 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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