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Finding cDNAs
UGID:229062     UniGene Hs.433951     Homo sapiens (human)   GPX4 Order cDNA clone, Links
Glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_002076.2 glutathione peroxidase 4 isoform A precursor H. sapiens 100.0 196
NP_728868.1 PHGPx CG12013-PC, isoform C D. melanogaster 46.5 169

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (2.8 pct) in cDNA library dbEST:8226, NT0147.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; lung; testis; eye; pancreas; prostate; uterus; liver; uncharacterized tissue; intestine; mixed; placenta; kidney; heart; skin; embryonic tissue; muscle; mammary gland; ovary; bone; bladder; stomach; parathyroid; lymph; thyroid; ascites; thymus; lymph node; larynx; blood; mouth; spleen; vascular; adrenal gland; pineal gland; nerve; connective tissue; salivary gland; cervix; adipose tissue; bone marrow; pharynx; pituitary gland; tonsil; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BC046163.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone MGC:57716 IMAGE:5742889), complete cds PA
BC058329.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone IMAGE:6527068) A
NM_002085.3 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 1, mRNA PA
CR619467.1 full-length cDNA clone CS0DK002YG24 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR618930.1 full-length cDNA clone CS0CAP002YL24 of Thymus of Homo sapiens (human) P
CR617590.1 full-length cDNA clone CS0DJ006YE24 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR608332.1 full-length cDNA clone CS0DC014YG09 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR595286.1 full-length cDNA clone CS0DI076YB13 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR591093.1 full-length cDNA clone CS0DB007YG10 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
NM_001039848.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 3, mRNA PA
NM_001039847.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant 2, mRNA PA
AK225859.1 Homo sapiens mRNA for Phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor variant, clone: FCC125B05 A
X71973.1 H.sapiens GPx-4 mRNA for phospholipid hydroperoxide glutathione peroxidase PA
BC032695.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone MGC:45347 IMAGE:5227887), complete cds PA
BC022071.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone MGC:33153 IMAGE:4821595), complete cds PA
BC021567.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone MGC:31923 IMAGE:4581069), complete cds PA
BC011836.2 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone MGC:20094 IMAGE:3945177), complete cds PA
BC010157.2 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone IMAGE:3617438), complete cds PA
BC039849.1 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase), mRNA (cDNA clone MGC:48873 IMAGE:5744771), complete cds PA

EST sequences (10 of 1071) [Show all sequences]

AA866106.1 Clone IMAGE:1470313 uncharacterized tissue 3' read A
AA888171.1 Clone IMAGE:1492142 kidney 3' read PA
AA975868.1 Clone IMAGE:1555645 kidney 3' read A
AA977808.1 Clone IMAGE:1591554 kidney 3' read PA
AA991230.1 Clone IMAGE:1607850 mammary gland 3' read A
AA991970.1 Clone IMAGE:1613566 uncharacterized tissue 3' read PA
AA992915.1 Clone IMAGE:1624234 embryonic tissue 3' read A
AA994017.1 Clone IMAGE:1628941 mixed 3' read A
AA887242.1 Clone IMAGE:1500339 lung 3' read PA
AA887529.1 Clone IMAGE:1500540 lung 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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