CARRA members represent the perspective of those whose lives are affected by cancer. By partnering with those who plan, manage, prioritize, and advance cancer research, CARRA members provide a concrete, valuable contribution: information and insights into the target audiences for that research.

For example, clinical trials depend on recruiting a large number of participants who fit certain criteria. If a research study is scientifically well designed but involves a treatment which cancer participants believe is not as beneficial as an existing treatment, or which involves so many invasive procedures that cancer patients do not think they could endure them, the study will not recruit participants. As an investment, its funding would not yield a positive return.

CARRA members are trained to participate in peer review groups evaluating the scientific and technical merit of research applications - to help ensure that proposed research studies are feasible for the target audiences for recruitment and have sufficient human subject protections.

While CARRA members are not expected to be scientists, they often know or learn some basic terminology and concepts to help them interact with the scientific staff and outside scientists who are also participating in their assigned activity.

Science/Research activities include: