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UGID:679495     UniGene Hs.464336     Homo sapiens (human)   P4HB
Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (P4HB)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_004825.2 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 H. sapiens 100.0 70
NP_730033.1 Protein disulfide isomerase CG6988-PD, isoform D D. melanogaster 72.6 189
NP_849696.1 ATPDIL1-1 (PDI-LIKE 1-1); protein disulfide isomerase A. thaliana 46.8 479

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in many libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; skin; kidney; placenta; prostate; uncharacterized tissue; lung; connective tissue; intestine; vascular; liver; mammary gland; uterus; spleen; pancreas; stomach; trachea; mouth; testis; embryonic tissue; eye; thyroid; blood; thymus; adrenal gland; ovary; mixed; heart; bladder; muscle; bone marrow; esophagus; bone; ascites; salivary gland; cervix; lymph; umbilical cord; lymph node; pharynx; adipose tissue; nerve; ear; tonsil; pituitary gland; amniotic fluid; larynx; bronchus; ganglia; parathyroid; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q25
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (31)

AK128783.1 Homo sapiens cDNA FLJ45462 fis, clone BRSTN2011961, highly similar to Protein disulfide-isomerase precursor (EC 5.3.4.1) P
NM_000918.3 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (P4HB), mRNA A
BC071892.1 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide, mRNA (cDNA clone MGC:88571 IMAGE:5443660), complete cds PA
CR625953.1 full-length cDNA clone CS0DF029YC04 of Fetal brain of Homo sapiens (human)
CR620228.1 full-length cDNA clone CS0DI039YG09 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR611495.1 full-length cDNA clone CS0DC006YN05 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)
CR609355.1 full-length cDNA clone CS0DF008YP24 of Fetal brain of Homo sapiens (human)
CR607735.1 full-length cDNA clone CS0DE011YL12 of Placenta of Homo sapiens (human) P
CR605884.1 full-length cDNA clone CS0DI006YC24 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR603259.1 full-length cDNA clone CS0DI003YG23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR602877.1 full-length cDNA clone CS0DI042YB16 of Placenta Cot 25-normalized of Homo sapiens (human)
CR600518.1 full-length cDNA clone CS0DI013YK03 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR592927.1 full-length cDNA clone CS0DI068YG09 of Placenta Cot 25-normalized of Homo sapiens (human) P
J02783.1 Human thyroid hormone binding protein (p55) mRNA, complete cds P
BC010859.1 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide, mRNA (cDNA clone MGC:9192 IMAGE:3879411), complete cds PA
BC014504.1 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide, mRNA (cDNA clone IMAGE:4861217), complete cds PA
X05130.1 Human mRNA for prolyl 4-hydoxylase beta subunit (EC 1.14.11.2) (procollagen-L-proline, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating) P
AK315631.1 Homo sapiens cDNA, FLJ96716, Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase(proline 4-hydroxylase), beta polypeptide (protein disulfideisomerase; thyroid hormone binding protein p55) (P4HB), mRNA
AK308600.1 Homo sapiens cDNA, FLJ98641
AB062434.1 Homo sapiens mRNA for OK/SW-CL.24, complete cds A
BC029617.1 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide, mRNA (cDNA clone MGC:9695 IMAGE:3848651), complete cds PA
AK095938.1 Homo sapiens cDNA FLJ38619 fis, clone HEART2007696, highly similar to Protein disulfide-isomerase precursor (EC 5.3.4.1) P
AK300561.1 Homo sapiens cDNA FLJ59430 complete cds, highly similar to Protein disulfide-isomerase precursor (EC 5.3.4.1)
AK298005.1 Homo sapiens cDNA FLJ59939 complete cds, highly similar to Protein disulfide-isomerase precursor (EC 5.3.4.1)
AK297967.1 Homo sapiens cDNA FLJ59361 complete cds, highly similar to Protein disulfide-isomerase precursor (EC 5.3.4.1)
AK297081.1 Homo sapiens cDNA FLJ59033 complete cds, highly similar to Protein disulfide-isomerase precursor (EC 5.3.4.1)
AK296206.1 Homo sapiens cDNA FLJ56766 complete cds, highly similar to Protein disulfide-isomerase precursor (EC5.3.4.1)
AK075503.1 Homo sapiens cDNA PSEC0201 fis, clone HEMBA1002107, highly similar to PROTEIN DISULFIDE ISOMERASE PRECURSOR (PDI) (EC 5.3.4.1) P
BC018801.1 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide, mRNA (cDNA clone IMAGE:3607959) A
AL357203.1 Homo sapiens EST from clone 375854, 5' end
X07077.1 Human mRNA for glutathione-insulin transhydrogenase (EC 5.3.4.1 / 1.8.4.2 ) P

EST sequences (10 of 5759) [Show all sequences]

AA910499.1 Clone IMAGE:1516868 uncharacterized tissue 3' read PA
AA971209.1 Clone IMAGE:1574879 kidney 3' read A
AA971416.1 Clone IMAGE:1584293 lung 3' read
AA983898.1 Clone IMAGE:1581542 mixed 3' read A
AA985609.1 Clone IMAGE:1593028 kidney 3' read A
AA991915.1 Clone IMAGE:1611334 uncharacterized tissue 3' read
AA996039.1 Clone IMAGE:1606853 kidney 3' read A
AI002250.1 Clone IMAGE:1601414 lung 3' read
AI003148.1 Clone IMAGE:1699935 kidney 3' read A
AI005547.1 Clone IMAGE:1637327 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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