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UGID:1371084     UniGene Hs.534770     Homo sapiens (human)   PKM2 Order cDNA clone, Links
Pyruvate kinase, muscle (PKM2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001175080.1 PREDICTED: pyruvate kinase 3 isoform 7 P. troglodytes 100.0 530
NP_002645.3 pyruvate kinase, muscle isoform M2 H. sapiens 100.0 530
NP_732723.1 Pyruvate kinase CG7070-PB, isoform B D. melanogaster 78.1 511
NP_001021412.1 F25H5.3d C. elegans 73.7 554
XP_959838.1 pyruvate kinase N. crassa 65.5 526

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in many libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; skin; kidney; lung; uncharacterized tissue; pancreas; testis; intestine; ovary; eye; uterus; embryonic tissue; prostate; connective tissue; liver; mammary gland; lymph; placenta; muscle; ascites; blood; cervix; mouth; heart; stomach; vascular; bone; salivary gland; thyroid; thymus; spleen; mixed; adrenal gland; bone marrow; tonsil; lymph node; bladder; trachea; larynx; esophagus; umbilical cord; pharynx; amniotic fluid; nerve; pineal gland; pituitary gland; ganglia; adipose tissue; epididymis; parathyroid; spinal cord; ear; peritoneum
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q22
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (36)

M23725.1 Human M2-type pyruvate kinase mRNA, complete cds P
M26252.1 Human TCB gene encoding cytosolic thyroid hormone-binding protein, complete cds P
NM_182471.1 Homo sapiens pyruvate kinase, muscle (PKM2), transcript variant 3, mRNA PA
NM_182470.1 Homo sapiens pyruvate kinase, muscle (PKM2), transcript variant 2, mRNA P
BX648597.1 Homo sapiens mRNA; cDNA DKFZp686G12209 (from clone DKFZp686G12209) PA
NM_002654.3 Homo sapiens pyruvate kinase, muscle (PKM2), transcript variant 1, mRNA PA
CR626740.1 full-length cDNA clone CS0DI005YD09 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR621899.1 full-length cDNA clone CS0DF028YA03 of Fetal brain of Homo sapiens (human) P
CR621722.1 full-length cDNA clone CS0DG007YD24 of B cells (Ramos cell line) of Homo sapiens (human) P
CR612091.1 full-length cDNA clone CS0DI018YI03 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR602413.1 full-length cDNA clone CS0DE003YE18 of Placenta of Homo sapiens (human)
CR592184.1 full-length cDNA clone CS0DA006YD04 of Neuroblastoma of Homo sapiens (human)
CR592076.1 full-length cDNA clone CS0DC027YH12 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)
AK222927.1 Homo sapiens mRNA for pyruvate kinase 3 isoform 1 variant, clone: HRC08174 P
BC094767.1 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone MGC:104654 IMAGE:5296639), complete cds PA
BC096823.1 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone IMAGE:30558692) PA
BC000481.2 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone MGC:8698 IMAGE:2964687), complete cds PA
BC007952.2 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone MGC:14360 IMAGE:4299213), complete cds PA
BC007640.1 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone MGC:15908 IMAGE:3533876), complete cds PA
BC012811.2 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone MGC:3932 IMAGE:2958817), complete cds PA
BC019265.2 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone IMAGE:3503708), partial cds PA
AK308264.1 Homo sapiens cDNA, FLJ98212
AK307855.1 Homo sapiens cDNA, FLJ97803
AK309781.1 Homo sapiens cDNA, FLJ99822
AK312253.1 Homo sapiens cDNA, FLJ92548, highly similar to Homo sapiens pyruvate kinase, muscle (PKM2), mRNA
AK092369.1 Homo sapiens cDNA FLJ35050 fis, clone OCBBF2018167, highly similar to Pyruvate kinase isozyme M1 (EC 2.7.1.40) P
AK294315.1 Homo sapiens cDNA FLJ56065 complete cds, highly similar to Pyruvate kinase isozyme M1 (EC 2.7.1.40)
AK300800.1 Homo sapiens cDNA FLJ54554 complete cds, highly similar to Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)
AK297951.1 Homo sapiens cDNA FLJ53368 complete cds, highly similar to Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)
AK299413.1 Homo sapiens cDNA FLJ53645 complete cds, highly similar to Pyruvate kinase isozyme M1 (EC 2.7.1.40) A
BC023592.2 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone IMAGE:4646848) PA
BC023328.1 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone IMAGE:4510296) PA
Z36831.1 H.sapiens (xs25) mRNA, 443bp P
Z36786.1 H.sapiens (xs130) mRNA, 260bp P
BC035198.1 Homo sapiens pyruvate kinase, muscle, mRNA (cDNA clone MGC:9369 IMAGE:3859987), complete cds PA
AF025439.1 Homo sapiens Opa-interacting protein OIP3 mRNA, partial cds PA

EST sequences (10 of 10780) [Show all sequences]

AA954688.1 Clone IMAGE:1554958 kidney 3' read A
AA961352.1 Clone IMAGE:1599484 uncharacterized tissue 3' read A
AA975644.1 Clone IMAGE:1591011 kidney 3' read A
AA976397.1 Clone IMAGE:1591526 kidney 3' read A
AA985355.1 Clone IMAGE:1629457 brain 3' read P
AA987302.1 Clone IMAGE:1602296 lung 3' read A
AI000757.1 Clone IMAGE:1613145 uncharacterized tissue 3' read A
AI015272.1 Clone IMAGE:1641224 testis 3' read A
AI033722.1 Clone IMAGE:1663478 skin 3' read
AI039372.1 Clone IMAGE:1658763 embryonic tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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