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UGID:2063455     UniGene Hs.594444     Homo sapiens (human)   LMNA
Lamin A/C (LMNA)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_733822.1 lamin A/C isoform 3 H. sapiens 100.0 633
NP_062263.1 lamin A isoform C2 M. musculus 99.1 460

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in many libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; skin; lung; connective tissue; uterus; placenta; uncharacterized tissue; kidney; mouth; pancreas; intestine; mammary gland; vascular; liver; prostate; testis; trachea; ovary; eye; heart; spleen; mixed; embryonic tissue; stomach; ascites; cervix; bone; adrenal gland; blood; esophagus; thymus; bladder; thyroid; salivary gland; adipose tissue; bone marrow; ganglia; muscle; larynx; umbilical cord; nerve; lymph node; amniotic fluid; pituitary gland; parathyroid; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21.2-q21.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (40)

M13452.1 Human lamin A mRNA, 3'end P
M13451.1 Human lamin C mRNA, complete cds P
AK130179.1 Homo sapiens cDNA FLJ26669 fis, clone MPG03096, highly similar to LAMIN A P
AK122732.1 Homo sapiens cDNA FLJ16247 fis, clone HCHON2003659, highly similar to LAMIN A P
NM_005572.3 Homo sapiens lamin A/C (LMNA), transcript variant 2, mRNA A
AY357727.1 Homo sapiens progerin mRNA, complete cds PA
CR626536.1 full-length cDNA clone CS0DI042YO15 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR623720.1 full-length cDNA clone CS0DK003YJ12 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR622626.1 full-length cDNA clone CS0DC004YE14 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR620993.1 full-length cDNA clone CS0DI067YJ19 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR619166.1 full-length cDNA clone CS0DI010YN06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR619146.1 full-length cDNA clone CS0DI015YC06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR605674.1 full-length cDNA clone CS0DC003YP02 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR604156.1 full-length cDNA clone CS0DA009YE08 of Neuroblastoma of Homo sapiens (human) P
CR603908.1 full-length cDNA clone CS0DI041YF19 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR600170.1 full-length cDNA clone CS0DM010YB09 of Fetal liver of Homo sapiens (human) P
CR598617.1 full-length cDNA clone CS0DK004YL13 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
AY847597.1 Homo sapiens lamin A/C transcript variant 1 (LMNA) mRNA, complete cds, alternatively spliced P
AY847596.1 Homo sapiens lamin A/C transcript variant 1 (LMNA) mRNA, complete cds, alternatively spliced P
AY847595.1 Homo sapiens lamin A/C transcript variant 1 (LMNA) mRNA, complete cds, alternatively spliced P
AY528714.1 Homo sapiens rhabdomyosarcoma antigen MU-RMS-40.12 mRNA, complete cds, alternatively spliced P
AK026584.1 Homo sapiens cDNA: FLJ22931 fis, clone KAT07501, highly similar to HSLAMAR Human mRNA for nuclear envelope protein lamin A precursor PA
BC000511.2 Homo sapiens lamin A/C, mRNA (cDNA clone MGC:8539 IMAGE:2822703), complete cds PA
BC003162.1 Homo sapiens lamin A/C, mRNA (cDNA clone MGC:4219 IMAGE:2958052), complete cds PA
AF381029.1 Homo sapiens lamin Adel10 mRNA, partial cds, alternatively spliced P
AK057997.1 Homo sapiens cDNA FLJ25268 fis, clone STM05518, highly similar to LAMIN A P
AK056191.1 Homo sapiens cDNA FLJ31629 fis, clone NT2RI2003360, highly similar to LAMIN A P
AK056143.1 Homo sapiens cDNA FLJ31581 fis, clone NT2RI2002091, highly similar to LAMIN C P
AK309539.1 Homo sapiens cDNA, FLJ99580
BC033088.1 Homo sapiens lamin A/C, mRNA (cDNA clone MGC:45654 IMAGE:3623265), complete cds PA
AK098128.1 Homo sapiens cDNA FLJ40809 fis, clone TRACH2009661, highly similar to LAMIN A P
AK097801.1 Homo sapiens cDNA FLJ40482 fis, clone TESTI2043656, highly similar to LAMIN C P
AK294217.1 Homo sapiens cDNA FLJ55771 complete cds, highly similar to Lamin-A/C
AK295390.1 Homo sapiens cDNA FLJ56081 complete cds, highly similar to Lamin-A/C
BC018863.2 Homo sapiens lamin A/C, mRNA (cDNA clone IMAGE:3141665) A
BC014507.1 Homo sapiens lamin A/C, mRNA (cDNA clone MGC:23638 IMAGE:4863480), complete cds PA
X03444.1 Human mRNA for nuclear envelope protein lamin A precursor P
X03445.1 Human mRNA for nuclear envelope protein lamin C precursor P
NM_170708.2 Homo sapiens lamin A/C (LMNA), transcript variant 3, mRNA A
NM_170707.2 Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA A

EST sequences (10 of 5407) [Show all sequences]

AA954802.1 Clone IMAGE:1574293 kidney 3' read
AA961132.1 Clone IMAGE:1575511 intestine 3' read A
AA961563.1 Clone IMAGE:1592632 kidney 3' read P
AA968781.1 Clone IMAGE:1593672 kidney 3' read P
R16152.1 Clone IMAGE:53164 brain 3' read PA
AA971500.1 Clone IMAGE:1584376 lung 3' read P
AA977289.1 Clone IMAGE:1589974 kidney 3' read
AA977422.1 Clone IMAGE:1590642 kidney 3' read P
AA903549.1 Clone IMAGE:1518241 uncharacterized tissue 3' read
AI002109.1 Clone IMAGE:1638036 testis 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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