Complement component 1, s subcomponent, Homo sapiens

Restricted Expression:

neonate [show more like this]

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]

Highly represented in several libraries

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

uterus; connective tissue; liver; lung; brain; intestine; spleen; thymus; testis; trachea; mouth; prostate; skin; stomach; pancreas; kidney; placenta; bladder; eye; uncharacterized tissue; heart; mammary gland; pituitary gland; vascular; ovary; bone; larynx; parathyroid; salivary gland; nerve; mixed; adrenal gland; esophagus; embryonic tissue; adipose tissue; cervix; pharynx; muscle; thyroid; ganglia; blood; lymph node; amniotic fluid; ear; tonsil; bone marrow

NCBI

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Finding cDNAs

UGID:627318 UniGene Hs.458355 Homo sapiens (human) C1S

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Complement component 1, s subcomponent (C1S)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001725.1	complement component 1, s subcomponent	H. sapiens	100.0	687

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	12
	Map position:	12p13

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK126711.1	Homo sapiens cDNA FLJ44757 fis, clone BRACE3031185
BC056903.1	Homo sapiens complement component 1, s subcomponent, mRNA (cDNA clone MGC:65134 IMAGE:6199186), complete cds	PA
NM_001734.2	Homo sapiens complement component 1, s subcomponent (C1S), transcript variant 1, mRNA	PA
NM_201442.1	Homo sapiens complement component 1, s subcomponent (C1S), transcript variant 2, mRNA	PA
J04080.1	Human complement component C1r mRNA, complete cds	P
M18767.1	Human complement subcomponent C1s, alpha- and beta-chains, complete cds	P
AK025309.1	Homo sapiens cDNA: FLJ21656 fis, clone COL08657, highly similar to HUMC1RS Human complement component C1r mRNA	PA
X06596.1	Human mRNA for complement component C1s	P
AK055183.1	Homo sapiens cDNA FLJ30621 fis, clone CTONG2001681, highly similar to Complement C1s subcomponent precursor (EC 3.4.21.42)	P
AK290295.1	Homo sapiens cDNA FLJ77835 complete cds, highly similar to Homo sapiens complement component 1, s subcomponent (C1S), transcript variant 2, mRNA
AM886411.1	Homo sapiens C1S mRNA, transcript variant 3

EST sequences (10 of 1889) [Show all sequences]

AA962643.1	Clone IMAGE:1553679	kidney	3' read	A
AA962833.1	Clone IMAGE:1573751	kidney	3' read	A
AA907389.1	Clone IMAGE:1521725	lung	3' read	A
AA910940.1	Clone IMAGE:1520775	kidney	3' read	PA
AI004956.1	Clone IMAGE:1624808	embryonic tissue	3' read	A
AI014489.1	Clone IMAGE:1607300	mammary gland	3' read
AA928324.1	Clone IMAGE:1553096	uncharacterized tissue	3' read	A
AI091012.1	Clone IMAGE:1689719	mixed	3' read	A
AI131489.1	Clone IMAGE:1709500	heart	3' read	A
CB052817.1	Clone IMAGE:3290521	uncharacterized tissue	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria