Testing Status of Agents at NTP
1,1-Dichloroethane
CASRN: 75-34-3
Formula: C2-H4-CL2
Synonyms/Common Names:
- ETHYLIDENE DICHLORIDE
Known Uses:
SOLVENT. CLEANING AGENT. FUMIGANT. CHEMICAL INTERMEDIATE. (TDB)
Short-Term Toxicity
- 14-Day (Gavage)
(C04535) Completed
- NTIS No. PB283345
(Peer Review 01/18/1978)
Citation: Bioassay of 1,1-Dichloroethane for Possible Carcinogenicity (CAS No. 75-34-3) - Rats: Osborne Mendel; Mice: B6C3F1
- NTIS No. PB283345
(Peer Review 01/18/1978)
- 13-Week (Gavage)
(C04535) Completed
- NTIS No. PB283345
(Peer Review 01/18/1978)
Citation: Bioassay of 1,1-Dichloroethane for Possible Carcinogenicity (CAS No. 75-34-3) - Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0,562,5620, M: 0,1000,10000 MG/KG/5 PER GROUP
- NTIS No. PB283345
(Peer Review 01/18/1978)
Long-Term Carcinogenicity
- 2-Year (Gavage)
(C04535) Report Complete
- TR-066 (NTIS No. PB283345)
(Peer Review 01/18/1978)
Bioassay of 1,1-Dichloroethane for Possible Carcinogenicity (CAS No. 75-34-3) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Equivocal
- Male Mice Negative
- Female Mice Equivocal
- Dose: MR: 0,382,764 (AVG), FR: 0,475,950 (AVG), MM: 0,1442,2885 (AVG), FM: 0,1665,3331 (AVG) MG/KG/50 PER GROUP
- TR-066 (NTIS No. PB283345)
(Peer Review 01/18/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(508873) Completed
- Chromosome Aberation Negative
- Sister Chromatid Exchange Positive
- Salmonella
(777132) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
- Negative
Web page last updated on January 22, 2009