3-D Reconstruction of the Rat Small Intestines for Modeling Nutrient Transport in the Gut [4 seconds]
To provide the surface boundary conditions for computer simulations of macro-micro mixing motions of the small intestine, we carry out dynamic imaging of gut motility using magnetic resonance imaging of the rat small intestines. Shown is a three-dimensional reconstruction of stacked multi-slice static images of the rat stomach, a rather long duodenum and a tangled jejunum and ileum. From these reconstructions we select sites for time-resolved single-slice imaging to obtain boundary conditions for the modeling. This research was funded by the National Science Foundation, as part of the Interagency Modeling and Analysis Group’s (IMAG) Multiscale Modeling Initiative. This initiative is administered by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), a part of the National Institutes of Health.
James G. Brasseur, Ph.D. and Andrew G. Webb, Ph.D.
Pennsylvania State University