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UGID:2224781     UniGene Hs.643610     Homo sapiens (human)   ACO2
Aconitase 2, mitochondrial (ACO2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_849166.1 PREDICTED: similar to aconitase 2, mitochondrial isoform 3 C. lupus familiaris 98.6 780
NP_650042.2 CG4706 CG4706-PA D. melanogaster 78.7 769

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (9.2 pct) in cDNA library dbEST:7829, HN0066.
Note: Highly represented (1.0 pct) in cDNA library dbEST:8019, MT0132.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; uncharacterized tissue; skin; lung; placenta; intestine; thyroid; uterus; eye; prostate; embryonic tissue; blood; mammary gland; liver; kidney; mixed; heart; testis; muscle; pancreas; esophagus; lymph; stomach; connective tissue; adrenal gland; epididymis; bladder; tonsil; ascites; bone; cervix; thymus; ovary; parathyroid; adipose tissue; lymph node; larynx; amniotic fluid; spleen; nerve; ganglia; pineal gland; mouth; bone marrow; salivary gland; ear; bronchus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q11.2-q13.31|22q13.2|22q13.2-q13.31
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

NM_001098.2 Homo sapiens aconitase 2, mitochondrial (ACO2), nuclear gene encoding mitochondrial protein, mRNA P
CR456365.1 Homo sapiens ACO2 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.ACO2) P
CR536568.1 Homo sapiens full open reading frame cDNA clone RZPDo834C0922D for gene ACO2, aconitase 2, mitochondrial; complete cds, incl. stopcodon P
CR621307.1 full-length cDNA clone CS0DK003YI09 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR619036.1 full-length cDNA clone CS0DA005YJ14 of Neuroblastoma of Homo sapiens (human) P
CR614581.1 full-length cDNA clone CS0DC016YG11 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)
CR613743.1 full-length cDNA clone CS0DI081YJ16 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR596641.1 full-length cDNA clone CS0DL005YJ10 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
CR596278.1 full-length cDNA clone CS0DK001YP12 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR596181.1 full-length cDNA clone CS0DF033YK22 of Fetal brain of Homo sapiens (human) P
CR595461.1 full-length cDNA clone CS0DF038YC17 of Fetal brain of Homo sapiens (human) P
CR592345.1 full-length cDNA clone CS0DI025YH21 of Placenta Cot 25-normalized of Homo sapiens (human) P
BC127659.1 Homo sapiens cDNA clone IMAGE:40119900
BC127658.1 Homo sapiens cDNA clone IMAGE:40119895
BC014092.2 Homo sapiens aconitase 2, mitochondrial, mRNA (cDNA clone MGC:20605 IMAGE:4328775), complete cds PA
AK314845.1 Homo sapiens cDNA, FLJ95737, highly similar to Homo sapiens aconitase 2, mitochondrial (ACO2), nuclear geneencoding mitochondrial protein, mRNA
BC026196.2 Homo sapiens aconitase 2, mitochondrial, mRNA (cDNA clone MGC:33908 IMAGE:5264179), complete cds PA
AK301321.1 Homo sapiens cDNA FLJ50886 complete cds, highly similar to Aconitate hydratase, mitochondrial precursor(EC 4.2.1.3)
AK293562.1 Homo sapiens cDNA FLJ60429 complete cds, highly similar to Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)
AK297213.1 Homo sapiens cDNA FLJ52327 complete cds, highly similar to Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)
AK296260.1 Homo sapiens cDNA FLJ54329 complete cds, highly similar to Aconitate hydratase, mitochondrial precursor(EC 4.2.1.3)
AK302691.1 Homo sapiens cDNA FLJ51705 complete cds, highly similar to Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)
U80040.1 Human nuclear aconitase mRNA, encoding mitochondrial protein, complete cds PA

EST sequences (10 of 1086) [Show all sequences]

AA977366.1 Clone IMAGE:1588960 kidney 3' read
AA994289.1 Clone IMAGE:1631213 mammary gland 3' read
R17339.1 Clone IMAGE:32399 brain 5' read P
AI022858.1 Clone IMAGE:1650624 parathyroid 3' read A
AI023955.1 Clone IMAGE:1650688 parathyroid 3' read
AI026837.1 Clone IMAGE:1645702 testis 3' read A
AI041836.1 Clone IMAGE:1667720 parathyroid 3' read P
R20672.1 Clone IMAGE:26524 brain 3' read A
AI079766.1 Clone IMAGE:1668573 parathyroid 3' read P
AI081081.1 Clone IMAGE:1679888 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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