NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Query Tips
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
dbEST
Trace Archive

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:198654     UniGene Hs.370408     Homo sapiens (human)   COMT Order cDNA clone, Links
Catechol-O-methyltransferase (COMT)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_009294.1 catechol-O-methyltransferase isoform S-COMT H. sapiens 100.0 220

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (2.3 pct) in cDNA library dbEST:8352, GN0163.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: skin; brain; placenta; mixed; eye; lung; pancreas; intestine; prostate; uncharacterized tissue; kidney; muscle; uterus; ovary; parathyroid; vascular; tonsil; connective tissue; blood; liver; mammary gland; lymph node; embryonic tissue; bladder; heart; salivary gland; bone; lymph; stomach; adrenal gland; thymus; mouth; testis; bone marrow; amniotic fluid; pituitary gland; thyroid; cervix; esophagus; ascites; nerve; ganglia; epididymis; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q11.21-q11.23|22q11.21
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (36)

AK130031.1 Homo sapiens cDNA FLJ26521 fis, clone KDN08050, highly similar to Catechol O-methyltransferase, membrane-bound form (EC 2.1.1.6) P
AK129492.1 Homo sapiens cDNA FLJ25981 fis, clone ADG06616
NM_007310.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant S-COMT, mRNA P
NM_000754.2 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant MB-COMT, mRNA P
CR456422.1 Homo sapiens COMT full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.COMT) P
CR456997.1 Homo sapiens full open reading frame cDNA clone RZPDo834E125D for gene COMT, catechol-O-methyltransferase; complete cds, incl. stopcodon P
CR625831.1 full-length cDNA clone CS0DI064YA23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR624969.1 full-length cDNA clone CS0DL003YF18 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
CR616943.1 full-length cDNA clone CS0DF026YH17 of Fetal brain of Homo sapiens (human) P
CR613786.1 full-length cDNA clone CS0DM010YO22 of Fetal liver of Homo sapiens (human) P
CR612917.1 full-length cDNA clone CS0DI063YG20 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR612170.1 full-length cDNA clone CS0DI044YO20 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR610886.1 full-length cDNA clone CS0DF037YI04 of Fetal brain of Homo sapiens (human) P
CR610047.1 full-length cDNA clone CS0DI058YC23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR609952.1 full-length cDNA clone CS0DI031YD24 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR603785.1 full-length cDNA clone CS0DL006YJ10 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
CR603360.1 full-length cDNA clone CS0DI032YD02 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR602287.1 full-length cDNA clone CS0DI063YL10 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR595297.1 full-length cDNA clone CS0DI077YA19 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR590298.1 full-length cDNA clone CS0DI073YI14 of Placenta Cot 25-normalized of Homo sapiens (human) P
BC100018.1 Homo sapiens catechol-O-methyltransferase, mRNA (cDNA clone MGC:110987 IMAGE:6163659), complete cds PA
BC000419.2 Homo sapiens catechol-O-methyltransferase, mRNA (cDNA clone MGC:8663 IMAGE:2964400), complete cds PA
EF217322.1 Homo sapiens clone A-16 catechol-O-methyltransferase isoform (COMT) mRNA, partial cds, alternatively spliced
EF217321.1 Homo sapiens clone A-10 catechol-O-methyltransferase isoform (COMT) mRNA, partial cds, alternatively spliced
EF212883.1 Homo sapiens clone T-29 catechol-O-methyltransferase isoform (COMT) mRNA, partial cds, alternatively spliced
EF103922.1 Homo sapiens catechol-O-methyltransferase transcript variant COMT_v7 (COMT) mRNA, alternatively spliced
EF103921.1 Homo sapiens catechol-O-methyltransferase transcript variant COMT_v4 (COMT) mRNA, alternatively spliced
EF103918.1 Homo sapiens catechol-O-methyltransferase transcript variant COMT_v3 (COMT) mRNA, alternatively spliced
EF103917.1 Homo sapiens catechol-O-methyltransferase transcript variant COMT_v2 (COMT) mRNA, alternatively spliced
EF103916.1 Homo sapiens catechol-O-methyltransferase transcript variant COMT_v1 (COMT) mRNA, alternatively spliced
BC011935.2 Homo sapiens catechol-O-methyltransferase, mRNA (cDNA clone MGC:20006 IMAGE:3503220), complete cds PA
AK290440.1 Homo sapiens cDNA FLJ76097 complete cds, highly similar to Homo sapiens catechol-O-methyltransferase (COMT), transcript variant MB-COMT, mRNA
BC005867.2 Homo sapiens catechol-O-methyltransferase, mRNA (cDNA clone MGC:4072 IMAGE:2964400), complete cds PA
M65212.1 Homo sapiens catechol-O-methyltransferase (COMT) mRNA, complete cds P
M65213.1 Homo sapiens catechol-O-methyltransferase (COMT) mRNA, 3' end
M58525.1 Homo sapiens catechol-O-methyltransferase (COMT) mRNA, complete cds P

EST sequences (10 of 933) [Show all sequences]

AA961273.1 Clone IMAGE:1564489 mixed 3' read
AA961464.1 Clone IMAGE:1579678 mixed 3' read
AA907025.1 Clone IMAGE:1505756 mixed 3' read
AA910412.1 Clone IMAGE:1505756 mixed 3' read P
AA977161.1 Clone IMAGE:1587336 uncharacterized tissue 3' read P
AA905800.1 Clone IMAGE:1505088 mixed 3' read P
AA908991.1 Clone IMAGE:1523041 mixed 3' read P
R18157.1 Clone IMAGE:30420 brain 5' read
AI016609.1 Clone IMAGE:1622989 embryonic tissue 3' read
AI016999.1 Clone IMAGE:1635260 kidney 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help