4-hydroxyphenylpyruvate dioxygenase, Homo sapiens

Restricted Expression:

liver tumor [show more like this]

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]

Highly represented (1.1 pct) in cDNA library dbEST:12555, L7N800102.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

liver; mixed; eye; brain; kidney; lung; uncharacterized tissue; cervix; testis; mammary gland

NCBI

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Finding cDNAs

UGID:131315 UniGene Hs.2899 Homo sapiens (human) HPD

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4-hydroxyphenylpyruvate dioxygenase (HPD)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_649225.1	CG11796 CG11796-PB, isoform B	D. melanogaster	69.0	293
XP_956614.1	4-hydroxyphenylpyruvate dioxygenase	N. crassa	58.1	407

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	12
	Map position:	12q24-qter

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_002150.2	Homo sapiens 4-hydroxyphenylpyruvate dioxygenase (HPD), mRNA	PA
AK057510.1	Homo sapiens cDNA FLJ32948 fis, clone TESTI2008014, highly similar to 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)	P
AK290826.1	Homo sapiens cDNA FLJ76150 complete cds, highly similar to Homo sapiens 4-hydroxyphenylpyruvate dioxygenase (HPD), mRNA
BC024287.1	Homo sapiens 4-hydroxyphenylpyruvate dioxygenase, mRNA (cDNA clone MGC:39261 IMAGE:5087393), complete cds	PA
BC014790.1	Homo sapiens cDNA clone IMAGE:3880247, containing frame-shift errors	A
X72389.1	H.sapiens mRNA for 4-hydroxyphenylpyruvate dioxygenase	PA

EST sequences (10 of 134) [Show all sequences]

R19384.1	Clone IMAGE:129959	mixed	3' read
CB156837.1	Clone L17N670205n1-4-F10	liver	5' read	P
CB157182.1	Clone L17N670205n1-7-C11	liver	5' read	P
CB162518.1	Clone L17N670205n1-24-H04	liver	5' read	P
CB163973.1	Clone L17N670205n1-38-B12	liver	5' read
CB163987.1	Clone L17N670205n1-38-D08	liver	5' read
CB164060.1	Clone L17N670205n1-37-C10	liver	5' read	P
CB164478.1	Clone L17N670205n1-48-C12	liver	5' read	P
CB158457.1	Clone L19N779227-1-D09	liver	5' read	P
CB106926.1	Clone L3SNU475-8-F12	liver	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria