Topoisomerase (DNA) II alpha, Mus musculus

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.2 pct) in cDNA library dbEST:8904, Kaestner ngn3 - -.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

embryonic tissue; pancreas; eye; mammary gland; brain; mixed; uncharacterized tissue; thymus; bone marrow; testis; intestine; spleen; lymph node; blood; lung; extraembryonic tissue; skin; prostate; inner ear; kidney; ovary; bone; tongue; molar; pituitary gland; dorsal root ganglion; nasopharynx; liver

NCBI

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Finding cDNAs

UGID:257514 UniGene Mm.4237 Mus musculus (mouse) Top2a

Links

Topoisomerase (DNA) II alpha (Top2a)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_863082.1	PREDICTED: similar to DNA topoisomerase II, alpha isozyme isoform 3	C. lupus familiaris	94.6	1532

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	11
	Map position:	11 D\|11 57.0 cM

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AK033321.1	Mus musculus 15 days embryo male testis cDNA, RIKEN full-length enriched library, clone:8030493B08 product:topoisomerase (DNA) II alpha, full insert sequence	P
AK028218.1	Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810021D13 product:topoisomerase (DNA) II alpha, full insert sequence	P
BC008170.1	Mus musculus topoisomerase (DNA) II alpha, mRNA (cDNA clone IMAGE:3257411), with apparent retained intron	PA
BC052538.1	Mus musculus cDNA clone IMAGE:6487462	P
BC057873.1	Mus musculus topoisomerase (DNA) II alpha, mRNA (cDNA clone IMAGE:5316982), partial cds	PA
BC094326.1	Mus musculus topoisomerase (DNA) II alpha, mRNA (cDNA clone IMAGE:6415166), complete cds	PA
AK138079.1	Mus musculus 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130086A08 product:topoisomerase (DNA) II alpha, full insert sequence	P
AK161381.1	Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4930521A06 product:topoisomerase (DNA) II alpha, full insert sequence	P
AK169723.1	Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430013D24 product:topoisomerase (DNA) II alpha, full insert sequence	P
D12513.1	Mus musculus mRNA for DNA topoisomerase II, complete cds	P
U01915.1	Mus musculus DNA topoisomerase IIalpha mRNA, partial cds	P
U01919.1	Mus musculus DBA/2 DNA topoisomerase IIalpha fusion protein mRNA, partial cds	P
NM_011623.2	Mus musculus topoisomerase (DNA) II alpha (Top2a), mRNA

EST sequences (10 of 983) [Show all sequences]

CA565048.1	Clone NIA:K0333C03_IMAGE:30057434	bone	5' read	P
CA567409.1	Clone NIA:K0413G08_IMAGE:30060367	bone marrow	5' read	P
CA568222.1	Clone NIA:K0425B11_IMAGE:30061462	bone marrow	5' read	P
CA568416.1	Clone NIA:K0427F02_IMAGE:30061693	bone marrow	5' read	P
CA568650.1	Clone NIA:K0431C09_IMAGE:30062048	bone marrow	5' read	P
CA568810.1	Clone NIA:K0433F12_IMAGE:30062279	bone marrow	5' read	P
CA771590.1		pancreas	5' read	P
CA772967.1		pancreas	5' read	P
CA774416.1		pancreas	3' read	A
BY019214.1	Clone G830034C20	mammary gland	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria