Karyopherin (importin) alpha 2, Mus musculus

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.6 pct) in cDNA library dbEST:17932, RIKEN full-length enriched mouse cDNA library, C57BL/6J egg 2 cells.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

embryonic tissue; eye; mixed; mammary gland; testis; pancreas; extraembryonic tissue; brain; fertilized ovum; ovary; bone marrow; thymus; kidney; uncharacterized tissue; molar; liver; pituitary gland; heart; lung; spleen; prostate; lymph node; muscle; tongue; dorsal root ganglion; bone; skin; inner ear; intestine; thyroid; stomach; spinal cord; adipose tissue; connective tissue

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Finding cDNAs

UGID:259329 UniGene Mm.12508 Mus musculus (mouse) Kpna2

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Karyopherin (importin) alpha 2 (Kpna2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_862111.1	PREDICTED: similar to Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) isoform 5	C. lupus familiaris	97.3	528
XP_001723009.1	PREDICTED: similar to Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) isoform 2	H. sapiens	96.2	528
NP_731378.1	karyopherin alpha3 CG9423-PB, isoform B	D. melanogaster	56.2	506
NP_001031011.1	importin alpha-1 subunit, putative (IMPA4)	A. thaliana	54.9	454
XP_960652.1	importin alpha subunit	N. crassa	51.6	533

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	11
	Map position:	11 E1

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK075952.1	Mus musculus ES cells cDNA, RIKEN full-length enriched library, clone:2410044B12 product:karyopherin (importin) alpha 2, full insert sequence	P
BC082280.1	Mus musculus karyopherin (importin) alpha 2, mRNA (cDNA clone MGC:91246 IMAGE:6334979), complete cds	PA
BC086789.1	Mus musculus cDNA clone IMAGE:30541036, containing frame-shift errors	PA
AK167551.1	Mus musculus 14 days embryo liver cDNA, RIKEN full-length enriched library, clone:I530020F22 product:karyopherin (importin) alpha 2, full insert sequence	P
AK166982.1	Mus musculus blastocyst blastocyst cDNA, RIKEN full-length enriched library, clone:I1C0026I21 product:karyopherin (importin) alpha 2, full insert sequence	P
AK166790.1	Mus musculus blastocyst blastocyst cDNA, RIKEN full-length enriched library, clone:I1C0013G15 product:karyopherin (importin) alpha 2, full insert sequence	P
AK166577.1	Mus musculus 1 cell embryo 1 cell cDNA, RIKEN full-length enriched library, clone:I0C0030N23 product:karyopherin (importin) alpha 2, full insert sequence	P
AK147135.1	Mus musculus 17 days embryo heart cDNA, RIKEN full-length enriched library, clone:I920184H24 product:karyopherin (importin) alpha 2, full insert sequence	P
AK139850.1	Mus musculus 2 cells egg cDNA, RIKEN full-length enriched library, clone:B020029F22 product:karyopherin (importin) alpha 2, full insert sequence	P
AK169283.1	Mus musculus 17 days embryo heart cDNA, RIKEN full-length enriched library, clone:I920170M07 product:karyopherin (importin) alpha 2, full insert sequence	P
NM_010655.3	Mus musculus karyopherin (importin) alpha 2 (Kpna2), mRNA	PA

EST sequences (10 of 763) [Show all sequences]

CA565405.1	Clone NIA:K0337G01_IMAGE:30057864	bone	5' read	PM
CA566600.1	Clone NIA:K0403C10_IMAGE:30059361	bone marrow	5' read	PM
CA568123.1	Clone NIA:K0424A02_IMAGE:30061345	bone marrow	5' read	PM
CA569918.1	Clone NIA:K0448H10_IMAGE:30063741	bone marrow	5' read	PM
CA750721.1	Clone IMAGE:6829217	brain	5' read	PM
CA772969.1		pancreas	5' read	P
CA772985.1		pancreas	5' read
CA774369.1		pancreas	3' read	A
BY002497.1	Clone 6620409O09	ovary	5' read	P
BY008023.1	Clone G4D0006B05	mixed	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria