Testing Status of Agents at NTP
Tetraethylthiuram disulfide
CASRN: 97-77-8
Formula: C10 H20 N2 S4
Synonyms/Common Names:
- TETRAETHYLTHIOPEROXYDICARBONIC DIAMIDE :((H2N)C(S))2S2: (9CI)
Known Uses:
RUBBER ACCELERATOR, VULCANIZER; FUNGICIDE, SEED DISINFECTANT (MERCK 1989)
Short-Term Toxicity
- 2-WEEK (Dosed-Feed)
(C02959) Completed
- NTIS No. PB298514
(Peer Review 12/13/1978)
Citation: Bioassay of Tetraethylthiuram Disulfide for Possible Carcinogenicity (CAS No. 97-77-8) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB298514
(Peer Review 12/13/1978)
- 13-WEEK (Dosed-Feed)
(C02959) Completed
- NTIS No. PB298514
(Peer Review 12/13/1978)
Citation: Bioassay of Tetraethylthiuram Disulfide for Possible Carcinogenicity (CAS No. 97-77-8) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,1500,6800, FM: 0,250,10000 PPM/5 PER GROUP - MM: 0,2000,8000 PPM/10 PER GROUP
- NTIS No. PB298514
(Peer Review 12/13/1978)
Long-Term Carcinogenicity
- 2-YEAR (Dosed-Feed)
(C02959) Report Complete
- TR-166 (NTIS No. PB298514)
(Peer Review 12/13/1978)
Bioassay of Tetraethylthiuram Disulfide for Possible Carcinogenicity (CAS No. 97-77-8) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: R: 0,300,600, MM: 0,500,2000, FM: 0,100,500 PPM/50 PER GROUP
- TR-166 (NTIS No. PB298514)
(Peer Review 12/13/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(038371) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Negative
- In Vitro Cytogenetics (CA/SCE)
(768765) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Not Tested
- Mouse Lymphoma
(986702) Completed
- Citation: McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
- Positive
- Salmonella
(748370) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
- Negative
Organ Systems Toxicity
- GD 7-14 Short-Term in vivo Repro. Tox. (Gavage)
(T0044) Completed
- NTIS No. PB83-257600
Citation: Screening of Priority Chemicals for Reproductive Hazards - F Mice: Swiss
- Dose: 4900 MG/KG BODY WEIGHT
- NTIS No. PB83-257600
Web page last updated on January 22, 2009